Amycolatopsis albispora: A4R43_32930
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Entry
A4R43_32930 CDS
T05547
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
aab
Amycolatopsis albispora
Pathway
aab00860
Porphyrin metabolism
aab01100
Metabolic pathways
aab01110
Biosynthesis of secondary metabolites
aab01120
Microbial metabolism in diverse environments
aab01240
Biosynthesis of cofactors
Module
aab_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
aab_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
aab00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
A4R43_32930
Enzymes [BR:
aab01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
A4R43_32930
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
A4R43_32930
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AXB46654
UniProt:
A0A344LF30
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Position
7031185..7032717
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AA seq
510 aa
AA seq
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MTPARKTTGRVAFVGSGPGDAGLLTVRAQELLGKAEVVVTDPDVPAGVLAFAHPDAEVRP
AVGDPAEVAKDLVNEAKSGRLVLRLVAGDPLTQPAAVAEVQAVAKTSAVFDVVPGVSPGA
AVPAYAGVALGGTHTEVDLRGEVDWAALAATGGPLVLHATSSHLAEAASALTEHGLAPAT
PVAVTSNGTINTQRTVDSTLASLSADAGELVGPLVVTVGQAAGQRSKLSWWESRALYGWK
VLVPRTKEQAGDMADRLHSHGATSHEVPTISVEPPRSPAQMERSVKGLVDGRYQWLVFTS
TNAVRAVWEKFEEFGLDARAFSGVKIACVGEATAAKVRSFGIIPELVPTGEQSSEGLLAE
FPPYDDVLDPVDRVLLPRADIATETLSAGLRERGWEIDDVTAYRTVRAAPPPAETREMIK
TGGFDAVCFTSSSTVRNLVGIAGKPHTRTLVACIGPKTAETATEFGLRVDVQPEVPNVTA
LVDALAAHAARLRAEGALPPPRKAKRARRS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgacccccgcgcgcaagaccaccgggcgcgtcgccttcgtgggctcgggccccggcgac
gccggtctgctgaccgtccgcgcccaggagttgctgggcaaggccgaggtcgtggtgacc
gatccggacgtacccgccggcgtgctggcgttcgcccaccccgacgccgaggtgcgcccc
gccgtgggggacccggccgaggtggccaaggacctggtcaacgaggcgaagtcgggccgg
ctggtgctccgcctggtcgccggtgacccgctgacccagcccgccgcggtggccgaggtg
caggccgtggccaagaccagcgccgtgttcgacgtggtgcccggggtttcgcccggcgcc
gccgtgcccgcctacgccggggtcgcgctcggcggcacgcacaccgaggtcgacctgcgc
ggtgaggtcgactgggccgcgctggccgccaccggtggcccgctggtgctgcacgccacc
tccagccacctcgccgaagccgcctccgcgctgaccgagcacgggctcgcgccggccacc
ccggtcgcggtcacctcgaacggcaccatcaacacccagcgcacggtggactcgacgctg
gcctcgctgtcggccgacgccggtgagctggtcggcccgctggtggtcaccgtcgggcag
gccgccgggcagcgctcgaagctgtcctggtgggagtcgcgcgcgctgtacggctggaag
gtgctggtgccgcggaccaaggagcaggccggcgacatggccgaccggctgcacagccac
ggcgccacctcgcacgaggtgccgaccatctcggtcgagccgccgcgcagcccggcgcag
atggagcgctcggtcaagggcctggtcgacggccgctaccagtggctggtgttcacctcc
accaacgcggtgcgcgcggtgtgggagaagttcgaggagttcggcctggacgcgcgggcg
ttctccggcgtgaagatcgcctgcgtcggcgaggccaccgcggcgaaggtgcgctcgttc
ggcatcattcccgagctggtgccgaccggtgagcagtcctcggagggcctgctggccgag
ttcccgccgtacgacgacgtgctggacccggtcgaccgggtgctgctgccgcgggcggac
atcgccaccgagacgctgtcggccgggctgcgcgagcgcggctgggagatcgacgacgtg
acggcctaccggaccgtccgcgccgcgccgccgccagccgagacccgcgagatgatcaag
accggcggtttcgacgcggtgtgcttcacctcgtcgtccaccgtgcggaacctggtcggc
atcgcgggcaagccgcacacccgcaccctggtggcctgcatcggcccgaagaccgcggag
acggcgaccgagttcggcctgcgcgtggacgtgcagccggaggtcccgaacgtgaccgcg
ctggtggacgcgctcgccgcgcacgccgcgcgcctgcgtgccgagggcgcactgcccccg
ccgcgcaaggccaagcgcgcccgccgttcgtaa
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