Amycolatopsis acidiphila: LWP59_02135
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Entry
LWP59_02135 CDS
T07896
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
aacd
Amycolatopsis acidiphila
Pathway
aacd00860
Porphyrin metabolism
aacd01100
Metabolic pathways
aacd01110
Biosynthesis of secondary metabolites
aacd01120
Microbial metabolism in diverse environments
aacd01240
Biosynthesis of cofactors
Module
aacd_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
aacd_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
aacd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
LWP59_02135
Enzymes [BR:
aacd01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
LWP59_02135
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
LWP59_02135
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GFIT
Motif
Pfam:
HEM4
TP_methylase
SEF14_adhesin
Motif
Other DBs
NCBI-ProteinID:
UIJ60511
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Position
412946..414478
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AA seq
510 aa
AA seq
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MTPARNTAGRVAFVGSGPGDAGLLTVRAQELLAKAEVVVTDPDVPAGVLATASADAEVRP
AVGEPGEVAKDLAGEAKAGRLALRLVGGDPLTLPAVVAEVQAVAKTSAVFEIVPGVSPGA
AVPAYAGIALGGTHTEVDVRGDVNWAGLAGTPGPIVLHATSAHLAEAAGALVEHGLTSQT
PVAVTSNGTINTQRTLDSTLATLAQDAGELVGPLVVTIGEAAGHRAKLSWWESRALYGWK
VLVPRTKEQAGEMAERLRQHGATSHEVPTISVEPPRSPAQMERSVKGLVDGRYQWIVFTS
ANAVRAVWEKFDEFGLDARAFSGVKIACVGEATAERVRAFGINPELVPKGEQSSDGLLAE
FPPYDDILDPVNRVLLPRADIATETLSAGLIDRGWEVDDVTAYRTVRAAPPPAETREMIK
TGGFDAVCFTSSSTVRNLVGIAGKPHTRTLVACIGPKTAETAVEFGLRVDVQPEKADIPH
LVDALAAHAAKLRAEGALPPPRKAKRTRRS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgacccccgcgcggaacaccgctgggcgcgtcgcgttcgtgggctcaggccccggcgac
gccggattgctgaccgttcgtgcccaggaactgctggccaaggccgaggtcgtggtgacc
gaccccgacgtgcctgccggtgtgctcgccactgccagcgcggacgccgaggtgcgtccc
gccgtcggcgaaccgggcgaggtggccaaggacctggccggtgaggcgaaggccgggcgg
ctcgcgctgcgcctggtcggcggcgacccgctgaccctgcccgccgtcgtcgccgaggtg
caggcggtggccaagaccagcgccgtgttcgagatcgtgcccggtgtgtcgccgggtgcc
gcggtgccggcgtacgccggtatcgcactcggcggcacgcacaccgaggtcgacgtccgc
ggcgacgtgaactgggccgggctggccggcacgccgggcccgatcgtgctgcacgcgacc
tcggcgcacctcgccgaggcggccggcgcgctcgtcgagcacggcctcacgtcgcagacg
cccgtcgcggtgacgtcgaacgggacgatcaacacgcagcgcaccctcgacagcaccctc
gccacgctggcgcaggacgccggcgagctcgtcggcccgctggtggtgaccatcggtgag
gcggccgggcaccgcgcgaagctgtcgtggtgggagtcgcgggcgctgtacggctggaag
gtgctggtgccgcgcacgaaggagcaggcgggcgagatggccgagcgcctgcgccagcac
ggtgcgacttcgcacgaggtgcccacgatctcggtcgagccgccgcgcagccccgcgcag
atggagcgctcggtgaagggcctggtcgacgggcggtaccagtggatcgtcttcacctcg
gccaacgcggtgcgcgcggtgtgggagaagttcgacgagttcggcctggacgccagggcg
ttctcgggcgtgaagatcgcctgtgtcggcgaggccacggcggagcgcgtgcgggcgttc
ggcatcaacccggagctggtgccgaagggcgagcagtccagtgacggattgctggcggag
ttcccgccgtacgacgacatccttgatccggtgaaccgggtgctgctgccgcgggccgac
atcgccacggagacgctgtcggcaggcctgatcgaccgaggctgggaagtcgacgacgtc
acggcgtaccggaccgtgcgagcggccccgccaccggcggagacccgcgagatgatcaag
accggcggtttcgacgcggtgtgcttcacatcgtcgtcgacggtgcggaacctggtcggc
atcgcgggcaagccgcacacgcgcaccctcgtggcgtgcatcggcccgaagaccgcggag
accgcggtggagttcggcctgcgggtggacgtccagccggagaaggcggacatccctcac
ctggtcgacgccctggccgcccacgcggcgaagctccgcgccgagggcgcgttgccgccg
ccccggaaggccaagcgcacgcgacgttcgtga
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