Arvicola amphibius (Eurasian water vole): 119809176
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Entry
119809176 CDS
T08327
Symbol
Pde8b
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00230
Purine metabolism
aamp01100
Metabolic pathways
aamp04927
Cortisol synthesis and secretion
aamp04934
Cushing syndrome
aamp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119809176 (Pde8b)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
119809176 (Pde8b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
119809176 (Pde8b)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
119809176 (Pde8b)
Enzymes [BR:
aamp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
119809176 (Pde8b)
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Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_3
PAS_4
PAS_8
Motif
Other DBs
NCBI-GeneID:
119809176
NCBI-ProteinID:
XP_038177969
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Position
3:52478868..52695126
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AA seq
780 aa
AA seq
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MDQQQSKRQVSSAEVHIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTP
ESALECFLDKHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQVSGDHEEAS
VLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEIT
SDDHVIQYVNPAFERMMGYRKGELLGKELADLPKSDKNRADLLDTINTCIKKGKEWQGVY
YARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHRIHRDSGDNSQTEP
HSFRHKSRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQE
NSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTK
NVHQSHSHLAMPITINDVPPSIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFG
VCEFLNCTETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDE
VAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIF
KNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAAESEGSDCECNPTGKNF
PENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRS
TCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2343 nt
NT seq
+upstream
nt +downstream
nt
atggaccagcagcagagcaagcgccaggtgtcttctgcggaggtacacatcgggcccatg
agactgacacaggaccccatccaggttttgctaatctttgccaaggaggatagtcagagt
gacggcttctggtgggcctgtgacagggctgggtacagatgcaacattgctcgcacccca
gagtcggcccttgagtgctttctggacaaacatcatgaaataattgtgatcgatcacagg
cagacccggaacttcgatgcagaagcggtgtgcaggtcaatccgggccaccaacccctct
gagcacaccgtgatcctggctgtggtttcacaagtatctggtgaccatgaagaggcctca
gttcttcctctcctccatgccggcttcaaccggagatttatggagaatagcagcataatt
gcttgctataatgaactgattcaaatagaacacggggaagttcgctcacagttcaaatta
cgggcctgtaattcagtgtttacagcgttagaccactgtcatgaagccatagaaataaca
agtgatgatcatgtgattcagtatgtcaaccctgcctttgagaggatgatgggctaccgc
aaaggggagctcctgggcaaagaactcgccgacctacctaagagtgacaagaaccgggca
gacctcctggacaccatcaatacgtgcatcaagaagggaaaggagtggcagggggtttac
tatgccagacggaaatccggggacagcatccaacagcacgtgaagatcaccccagtgatt
ggccaaggagggaaaattaggcactttgtctccctcaagaagctgtgctgtaccactgac
aataacaagcagattcacaggattcatcgtgattccggggataactctcaaacagagcct
cattcattcagacacaagagcaggaggaaagagtccattgatgtgaaatcaatatcttcc
cgaggcagtgatgctccaagcctacagaatcgccgctacccctccatggcgaggattcac
tccatgaccatagaggcccccatcacaaaggttataaatataatcaatgcggctcaagaa
aacagcccggttacagtagcagaagccttggatagagtactagaaattttacggaccaca
gaactgtactcccctcagctgggaaccaaagatgaagaccctcacaccagtgatcttgtc
ggaggcctgatgactgatggcttgagaagactgtcagggaatgagtatgtgttcacaaag
aatgtgcaccaaagtcacagccaccttgccatgcctatcaccatcaacgatgtcccccct
agtatcgcccagttacttgataatgaagaaagctgggacttcaatatctttgaattggaa
gccgttacacataaaaggccattggtgtacctgggcttaaaggtcttctctcggtttgga
gtatgtgagtttttaaactgtactgaaaccactcttcgggcctggctgcaagtgattgaa
gccaactaccactcctccaatgcctaccacaattccacccatgctgccgacgtcctccat
gccactgctttcttcctcggaaaggaaagagtgaagggaagccttgaccagctggatgag
gtagctgctctcattgctgcgacagttcacgatgtggaccaccctggaagaaccaactcc
ttcctgtgcaacgcaggcagcgagctcgccgtgctctacaatgacactgcagtcctggag
agtcaccacacagccctggccttccagctcaccgtcaaagacaccaagtgcaacattttc
aagaatattgacaggaaccattaccgaacgctacgccaggctatcatcgacatggttttg
gccacggagatgacgaaacactttgaacatgtgaacaaatttgtgaacagcatcaacaag
ccactggcagctgagagcgagggcagcgactgtgaatgcaaccccactgggaagaacttc
cccgagaaccagatcctgatcaagcgcatgatgattaagtgtgctgacgtagccaaccct
tgccgacccttggacctgtgcattgagtgggctgggaggatctccgaggagtattttgcg
cagaccgatgaggagaagaggcaggggctacctgtggtgatgccagtgttcgaccgcagc
acctgcagcatccccaagtcccaaatctccttcattgactacttcatcacagacatgttc
gacgcgtgggacgcctttgcacacctgccagccctgatgcagcacttggcagacaactac
aaacactggaagacactggatgacctcaagtgcaaaagtctgagacttccgtctgacagc
taa
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