Arvicola amphibius (Eurasian water vole): 119811901
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Entry
119811901 CDS
T08327
Symbol
Jak3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp04062
Chemokine signaling pathway
aamp04151
PI3K-Akt signaling pathway
aamp04217
Necroptosis
aamp04550
Signaling pathways regulating pluripotency of stem cells
aamp04630
JAK-STAT signaling pathway
aamp04658
Th1 and Th2 cell differentiation
aamp04659
Th17 cell differentiation
aamp05161
Hepatitis B
aamp05162
Measles
aamp05166
Human T-cell leukemia virus 1 infection
aamp05169
Epstein-Barr virus infection
aamp05200
Pathways in cancer
aamp05203
Viral carcinogenesis
aamp05223
Non-small cell lung cancer
aamp05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
119811901 (Jak3)
04151 PI3K-Akt signaling pathway
119811901 (Jak3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
119811901 (Jak3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
119811901 (Jak3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
119811901 (Jak3)
04659 Th17 cell differentiation
119811901 (Jak3)
04062 Chemokine signaling pathway
119811901 (Jak3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119811901 (Jak3)
05203 Viral carcinogenesis
119811901 (Jak3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
119811901 (Jak3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
119811901 (Jak3)
05161 Hepatitis B
119811901 (Jak3)
05162 Measles
119811901 (Jak3)
05169 Epstein-Barr virus infection
119811901 (Jak3)
09163 Immune disease
05340 Primary immunodeficiency
119811901 (Jak3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aamp01001
]
119811901 (Jak3)
Enzymes [BR:
aamp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119811901 (Jak3)
Protein kinases [BR:
aamp01001
]
Non-receptor tyrosine kinases
JAK family [OT]
119811901 (Jak3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
Kdo
Kinase-like
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
119811901
NCBI-ProteinID:
XP_038181999
LinkDB
All DBs
Position
4:complement(105248797..105262667)
Genome browser
AA seq
1127 aa
AA seq
DB search
MRCGLPAPTLRSAAQEEKGPNFPLVVLMAPPSEETPLIPQRSCSLSSSEAGSLHVLLPPR
GSGPPQRLSFSFGDYLAEDLCVRAAKVCGILPVYHPLFALATEDLSRWFPPSHIFSVEDV
DIQVLVYRLRFYFPDWFGLETCHRFGLRKDLTSAILDLHVLEHLFAQHRSDLVSGRLPVG
LSLKEQGECLSLAVLDLAQMAREQAQRPGELLKTVSYKACLPPGLRDLIQGLSFVTRRRI
RRTVLQALRRVVTCQADRYSLMAKYILDLERLHPAAAAETFRVGLPVTQEGPGLLRVAGG
SGVAWSPGDQELFQTFCDFPEIVDVSIKQAPRMGPAGEHRLVTVTRMDSHILEAEFPGLP
EALSFVALVDGYFRLTCDSRHFFCKEVAPPRLLEEVAEMCHGPITSDFAVHKLKTAGSLP
GSYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRRDPTGAFSLVGLSQPHRSLRELLAA
CCHSGLHVDGAALNLTSCCAPRPKEKSNLIVVRRGCTPSPTPSRTPSCCTLMQLSFHTIP
ADSLEWHENLGHGSFTKIYRGCRREAVDGETHETEVLLKVMDARHRNCMESFLEAASLMS
QVSYPHLVLLHGVCMAGDSIMVQEFVYLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNY
LEDKGLPHGNVSARKVLLAREGVDGSPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQ
EARALGLEADKWGFGATAWEVFSGGPVHITSLEPAKKLKFYEDRGQLPAPKWTELAGLIA
QCMAYDPGQRPSFRAILRDLNGLITSDYELLSDPTPGSLSPRDELCTGTQLYACQDPTIF
EERHLKYISLLGKGNFGNVELCRYDPLGDNTGPLVAVKQLQHSGPDQQRDFQREIQILKA
LHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLHSGRLLLFAWQICKGM
EYLGARRCVHRDLAARNILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPE
SLSDNIFSCQSDVWSFGVVLYELFTYSDKSCSPSAEFLRMMGPERDGLALCRLLELLAEG
RRLPRPPACPTEVQELMQLCWAPSPQDRPTFGTLSPQLDALWRGNPG
NT seq
3384 nt
NT seq
+upstream
nt +downstream
nt
atgcgctgcgggctccctgcccccactctccggtccgcggcgcaggaggaaaagggcccg
aactttcctttggttgtactcatggcacctccaagtgaggagacgcctctgatccctcag
cgttcttgcagcctctcatcctcagaggcaggctccctgcatgtcctccttcctccgcgg
ggatctgggcctccccagcgactgtcattctcttttggggactacttggcagaggatttg
tgtgtgcgggcagccaaagtctgtggcatcctgcctgtttatcacccgctcttcgctctg
gcaaccgaggacttgtctcgctggttccccccaagccacatcttctctgtggaggacgtg
gacattcaagtcttggtctacaggctccggttttatttccctgactggtttggactggag
acatgtcaccgctttgggctgcgcaaagatctgaccagcgccatacttgacttacacgtt
ctagaacacctctttgcccagcaccgcagtgacctggtgagtgggcgcctcccagtgggc
ctcagcctgaaggagcagggagagtgcctgagcctggccgtgctggacctggcgcagatg
gcccgtgagcaggcccagaggccaggcgagctgctgaagaccgtcagctacaaggcctgc
ctgccacccggcctgcgcgacctgatccagggtctgagcttcgtgacaagaaggcgaatc
cgcaggacggtgctccaggcgttgcgccgcgtggtcacctgccaggccgaccgctactcg
ctcatggccaagtacatcctggacctggagaggctgcacccggcggccgccgccgagacc
ttccgcgtggggctcccggtaacccaggaggggccagggctcctgcgcgtggctgggggc
agcggcgtcgcctggagccccggggaccaagagcttttccagaccttctgtgactttccc
gaaatcgtggacgtcagcatcaagcaggccccacgcatgggtccggcaggggagcatcgg
ctggtcaccgttaccaggatggacagccacatcctggaagcagaattccccgggctgcct
gaggcactatccttcgtggccctcgtagatggttacttccgcctgacctgcgactccagg
catttcttctgcaaggaggtagcaccgccaaggctgttggaggaggtggcagagatgtgc
cacggacccatcacgtcagacttcgctgtccacaaactaaagaccgctggctccctcccg
ggctcctacattctccgccgcagccctcaggactatgacagctttcttctcactgcctgc
gtccagacgccccttggcccagactacaagggctgcctcatccgccgggaccccaccggg
gccttctccctggtcggcctcagccagccgcaccgaagcctccgggagctcctcgcagcc
tgctgtcattctgggctgcatgtagatggtgccgccctgaacctcacatcctgctgtgcc
cccagacccaaggaaaagtccaatttgatcgtggtaagaaggggctgcaccccttcccca
acccctagccgcaccccgtcctgctgcactctaatgcagctgagcttccacacgatccct
gcggacagcctggagtggcacgagaacctgggccacggctctttcaccaagatctaccgc
ggctgccggcgggaggccgtggatggcgagacacacgagacggaagtcctcctgaaggtc
atggacgccagacaccggaactgcatggagtcctttctagaagccgcgagcctgatgagc
caagtatcctacccgcacctcgtgttgctgcatggcgtctgcatggctggagacagcatc
atggtgcaggaatttgtctatctcggcgcaattgatatgtacctgcgcaagcgtggtcac
ttggtgccggccagctggaagctgcaggtggtcaagcagctggcctatgccctcaactat
ttggaggacaaaggcctccctcatggcaatgtctcagcgcggaaggtgctcctggctcga
gagggggttgatgggagtcctcccttcatcaagctgagtgatcctggcgtcagccccaca
gtgctgagcctagaaatgctcaccgacaggatcccctgggtggcccccgagtgtctgcag
gaagcccgggcgctcggcttagaggccgacaagtggggcttcggcgccaccgcgtgggag
gtgttcagtgggggacccgtgcacatcacctcgctggagcccgccaagaagctgaaattc
tacgaggaccgggggcagctgccggcccccaagtggacggagctggcgggactcattgcg
cagtgcatggcttacgacccgggccagcggccctccttccgcgccatcctcagggatctc
aacggcctcattacgtcagattatgagctcctctcagacccgacgcccggcagcctgagt
ccccgagatgagctgtgcaccggcacccagctctacgcctgccaggaccccaccatcttc
gaggagaggcaccttaaatacatctctctgttgggcaaaggcaactttggcaacgtggaa
ctgtgccgctatgaccctctgggggacaatacaggacccctggtagctgtgaagcagcta
cagcacagcgggccagaccagcagagggacttccagagggagattcagatcctcaaggcg
ctgcacagtgacttcatcgtcaagtaccggggagtcagctacgggccaggtcgccagagc
ctgcggttggtgatggagtacctgcccagcggctgcctgcgggacttcctgcagcgccac
cgcgcgcgcctgcactccggccgcctgctgctgttcgcttggcagatctgcaagggcatg
gagtacctgggcgcgcgccgctgcgtgcaccgcgacctggctgcgcgaaatattctggtg
gagagcgaggcgcacgtgaagatcgcggatttcggccttgctaagctgctgccgctcgga
aaggactactacgtggtccgcgagccaggccagagccccatcttctggtacgccccagaa
tccttgtccgacaacatcttctcctgccagtctgacgtgtggagcttcggcgtggtattg
tatgagctcttcacctatagcgacaagagctgcagcccttcggccgagttcttgcgcatg
atgggaccagagcgtgatgggcttgcgctctgcagactcctggagctgctggcagagggc
cgccgcctcccacggcctcctgcctgccccactgaggttcaggagctcatgcagctgtgc
tgggcgcccagcccgcaggaccggccgaccttcggcaccctgagcccgcagctggacgcg
ctgtggcgtggaaaccccgggtag
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