Actinoalloteichus sp. GBA129-24: UA75_02335
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Entry
UA75_02335 CDS
T04619
Name
(GenBank) uroporphyrinogen-III synthase/uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
acti
Actinoalloteichus sp. GBA129-24
Pathway
acti00860
Porphyrin metabolism
acti01100
Metabolic pathways
acti01110
Biosynthesis of secondary metabolites
acti01120
Microbial metabolism in diverse environments
acti01240
Biosynthesis of cofactors
Module
acti_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
acti_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
acti00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
UA75_02335
Enzymes [BR:
acti01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
UA75_02335
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
UA75_02335
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
NAS
Motif
Other DBs
NCBI-ProteinID:
APU18506
UniProt:
A0A1L7F113
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Position
513332..514861
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AA seq
509 aa
AA seq
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MTRARKIPGRIAFVGTGPGDAGLLTVRAKEVLKAASLVVTDPDVSAEAASLVSADAEVRP
AVGDPADVAKDMVAEAKNGRPVVRLVSGDPFTADAVVREAQAVSRTTIAFDVVPGVAGAT
AVPAYAGVALGAVHTEADVRGTMDWAALAAAPGTLVLHASGSHLAEAASSLVEHGLAPQT
PVAVTADGTTFTQRTIDTTLASLASVAGDLLGPLVITVGSAVAGRQKLSWWESRALYGWK
VLVPRTKDQAGAMSDRLRAHGAIPVEVPTISVEPPRSPAQMERAVKGLVDGRYQWVVFTS
TNAVRAVWEKFREFGLDARAFSGVKIACVGESTAEKVRSFGIIPELVPSGEQSSEGLLAD
FPPYDDILDPVDRVLLPRADIATETLAAGLRDRGWEIDDVTAYRTVRAAPPPADTREMIK
TGGFDAVCFTSSSTVRNLVGIAGKPHSRTLVACIGPATAETATEFGLRVDVQPEVAQVSS
LVDALASHAARLRSEGALPPPRKAKRARR
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgacccgtgcacgcaagatccccggacgtatcgccttcgtgggcactggccccggagac
gcgggactcctcaccgtccgggctaaagaagtactgaaagcggcctcgctcgtggtcacc
gatcccgacgtgtccgccgaggcggcctcgctggtctcggcggacgccgaggtccggccc
gcggtcggcgatcctgccgacgtggccaaggacatggtcgccgaggcgaagaacggtcgc
cccgtcgtccgcctcgtctcgggtgacccgttcaccgccgacgcggtggtgcgggaggct
caggcggtgtcgcgcaccacgatcgccttcgacgtggtccccggcgtcgccggtgccacg
gcggtgcccgcctacgcgggggtggcgctcggggcggtgcacaccgaggccgacgtccga
ggaacgatggactgggcggccctggccgcagcaccgggaaccctggtgctgcacgcctcg
ggcagtcacctggcggaggcggcgtcgtcactggtggaacacggcctcgcgccgcagacc
ccggtggccgtcacggccgacggaacgacgttcacgcagcgcacgatcgacacgacgctg
gcctcactggcctcggtggcgggggacctgctgggtccgctggtgatcaccgtgggctct
gccgtggccggtagacagaagctgtcctggtgggaatcgcgtgccctgtacggctggaag
gtcctggtgccgcgaaccaaggaccaggcgggcgcgatgagcgaccggctccgggcgcac
ggcgcgatccccgtggaggttccgaccatctcggtcgagccgccgcgcagcccggcccag
atggagcgggcggtcaagggactggtcgacgggcgctaccagtgggtggtgttcacctcg
accaatgcggttcgtgccgtgtgggagaagttccgcgagttcggcctggacgccagggcc
ttctccggggtcaagatcgcctgtgtcggcgagtccacggcggagaaggtgcggtccttc
ggcatcatccccgagctggttccctccggggagcagtccagcgagggtctgctggcggac
ttcccgccctacgacgacatcctcgacccggtggaccgggtgctgctgcccagggccgac
atcgccaccgagacgctcgcggcgggtctgcgcgatcgaggctgggagatcgacgacgtc
accgcgtaccggacggtgcgggcggctccgccgcctgccgacactcgcgagatgatcaag
acgggcgggttcgacgcggtgtgcttcacctcgtcgtcgaccgtccgcaacctggtcggc
atcgcgggcaagccgcactcccggaccctggtggcctgtatcggcccggccaccgccgag
acggcgaccgagttcggcctgcgggtcgacgtgcagcccgaggtcgcgcaggtctcctcg
ctggtggacgcactggcctcgcacgcggctcgactgcgttccgagggcgccctgccgccg
ccgcgtaaggccaagcgggctcgccgctag
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