Actinoalloteichus sp. GBA129-24: UA75_21855
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Entry
UA75_21855 CDS
T04619
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) beta subunit
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
acti
Actinoalloteichus sp. GBA129-24
Pathway
acti00280
Valine, leucine and isoleucine degradation
acti00640
Propanoate metabolism
acti00785
Lipoic acid metabolism
acti01100
Metabolic pathways
acti01110
Biosynthesis of secondary metabolites
acti01210
2-Oxocarboxylic acid metabolism
Module
acti_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
acti00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
UA75_21855
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
UA75_21855
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
UA75_21855
Enzymes [BR:
acti01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
UA75_21855
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
PFOR_II
DUF969
Motif
Other DBs
NCBI-ProteinID:
APU22360
UniProt:
A0A1L7FBZ3
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All DBs
Position
complement(5134437..5136650)
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AA seq
737 aa
AA seq
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MTKNPVDEYFLTEIAGLAAVDPVDPDAPIPGHPGVTGTRLLSLFDAQAGSRHLDLAARAL
GAAGQGFYSIGSSGHEGNAAVAAALRPTDPALLHYRSGAFYLERAAQVPGQRPLRDVLLG
VVAAAAEPISGGRHKVFGNRDLDVIPQTSTIASHLPRAVGLAFALERAKSIGVATDRPSD
AVVVCSLGDASANHSTATGAINAAMHCAYQGVPLPLLFVCEDNGIGISVRTPAGWIGRSH
RDRPGLEYLEADGSDLPAALEVARTAVDRVRSERRPVFLRLSTVRLMGHAGSDLESGYRS
RTEILADHARDPVTSTARLLVNAGVVTPGRLLDRYEELRAEVAAVAAEAVTLPKLTSAAE
IVRPLALPRAAETARRAASAAPVARRAAAFPDGLPESEGPLTLAQSVNRSLADLLAADDG
VLVFGEDVGRKGGVYGVTKGLRQRFGRLRVFDTLLDEQSVLGTALGAGLAGLLPIPEIQY
LAYLHNAADQLRGEAATLRFFSAGQYRNPMVVRVAGYGYQKGFGGHFHNDNGVAALRDVP
GLVVASPSRPDDAAAMLRTCVAAARVDGAVCVFLEPIALYHTRDLYEDGDGAWAAPYPVP
ASPAGAVPIGRARRYGDGPDLTLVSFGNGLRMSLRVAHRLAEQGVGARVVDLRWLAPLPV
ADLVAEAEATGRVLVVDETRRSGGVSEGVVTALVDHGFHGRLRRVTSEDSFIPLGRAAER
VLVDEATIEAAALDMLA
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
gtgacgaagaacccggtggacgagtacttcctgaccgagatcgcggggcttgccgccgtc
gaccccgtcgacccggacgcgccgatccccggccaccctggcgtgaccggtactcggctg
ctcagcctcttcgatgcgcaggccggaagtcggcacctcgatctcgccgcgcgcgccctc
ggtgcggcgggccaggggttctacagcatcggatcgtccggtcacgagggcaacgcggcc
gtggccgccgcgctgcggccgaccgatcccgcactgctgcactaccgttccggcgccttc
tacctggagcgcgccgcccaggtgccggggcagcgcccgctgcgggacgtgctgctcggc
gtcgtggcggcagcggcggaaccgatctcgggcggcaggcacaaggtcttcggcaaccga
gatctcgacgtcatcccgcagacctccacgatcgcctcgcatctgccgcgtgccgtcggc
ctcgccttcgcgttggagcgggccaagagcatcggcgtcgcgaccgaccggccctcggac
gcggtggtcgtctgcagtctcggcgacgcgtcggccaaccattccacggcgaccggggcg
atcaacgccgcgatgcactgtgcctaccagggcgtgccgttgccgttgctgttcgtctgt
gaggacaacggcatcgggatcagcgttcgcaccccggcaggctggatcggccgaagccac
cgggaccgccccggcctcgagtacctggaggcggacggctccgacctgcctgccgcgctc
gaggtcgccaggacggccgtcgaccgggtgcgcagcgagcggcgtccggtgttcctgcgg
ctgtcgacggtgcggctgatgggtcacgcgggctccgacctcgagtccgggtaccgcagc
cggacggagatcctggccgaccacgcacgagacccggtgaccagcacggcccgcctgctg
gtgaacgcgggcgtcgtcacgccgggtcggctcctcgaccgttacgaggagctgcgggcc
gaggtcgctgcggtcgcggcggaggcggtcacgctgccgaagctgacctcggcggcggag
atcgtccgtccccttgctctgccgcgtgcggcggagacggcgcggcgagcggcgtcggcg
gcgcccgtcgcgcgccgcgcggcggcgtttccggacggactcccggagtcggagggcccg
ctcaccctcgcccagtccgtcaaccggtcgctggccgacctgctcgccgcagacgacggc
gtgctcgtcttcggtgaggacgtcgggcgcaagggcggcgtctacggcgtcacgaagggg
ctgcggcagcgattcggcaggctccgggtcttcgacacgctgctggacgagcagagcgtg
ctgggcaccgcactgggtgcgggcctcgcaggcctgctcccgatcccggagatccagtac
ctcgcctacctgcacaatgccgccgatcagctccgaggcgaggccgcgacactccggttc
ttctccgccgggcagtaccggaacccgatggtcgtgcgggtggcgggctacggctatcag
aagggcttcggcgggcacttccacaacgacaacggggtggcggcactccgggacgtgccc
ggcctggtggtggcctcgccgtctcggccggatgacgcggccgcgatgttgcgaacctgc
gtcgccgccgctcgtgtcgacggcgcggtgtgtgtcttcctcgagccgatcgcgctctat
cacactcgtgacctgtacgaagacggcgacggtgcctgggcggcgccgtatccggtaccg
gcgagccccgccggagcggtgccgatcgggcgggcccgccgttatggcgacggcccggac
ctcaccctggtcagcttcggcaacggactgcggatgagccttcgggtggcccaccggctg
gcggaacagggcgtcggggcgcgcgtggtggacctgcgctggctggcgccgctgccggtc
gcagacctggtggccgaagccgaggcgaccggccgggtcctggtggtggacgagacacgg
cgcagcgggggtgtgtccgaaggggtcgtgaccgcgctcgtcgaccacggcttccacggg
cggcttcgacgcgtgaccagcgaggacagcttcattccactcggcagggccgccgaacgg
gtgctggtggacgaggcgaccatcgaggcagccgcgctggacatgctggcctga
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