Actinoplanes sp. N902-109: L083_7645
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Entry
L083_7645 CDS
T02655
Symbol
hemD
Name
(GenBank) uroporphyrinogen iii synthase hem4
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
actn
Actinoplanes sp. N902-109
Pathway
actn00860
Porphyrin metabolism
actn01100
Metabolic pathways
actn01110
Biosynthesis of secondary metabolites
actn01120
Microbial metabolism in diverse environments
actn01240
Biosynthesis of cofactors
Module
actn_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
actn_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
actn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
L083_7645 (hemD)
Enzymes [BR:
actn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
L083_7645 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
L083_7645 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AGL21155
UniProt:
R4M0W9
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All DBs
Position
complement(8633552..8635138)
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AA seq
528 aa
AA seq
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MTTRTARNRAGRIAFVGAGPGDPGLLTRRAHDTLADADQVVYDRGVPESLLAAIRAEAKD
DTQFSPAEGAPGDVAKVLLSAAKSGLSAVHLVAGDPFGHESVVNEVQAVARTAVHFEVVP
GIGQAEGVATYAGVPLPAVRTAADVDDVTALDFDALAAAALKGSFAVAVDAGDLAAVRDG
LLASGVEPGTPVGVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGGDVAERDKLSW
WENRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVD
GRYAWVVFTSVNAVRAVWEKFGEHGLDARHFGGVKIACIGEATADAVRAFGIQPELIPAD
DQSSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLIERGWEVDDVTAYRTVRAAP
PPADIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVD
VQPQHASVPDLVEALASYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgaccacccgcaccgcccgcaaccgcgccggacgcatcgcgttcgtcggcgccggaccc
ggcgacccggggctgctgacgcgccgggcccacgacaccctcgccgacgccgaccaggtc
gtctacgaccgcggcgtccccgagtcactgcttgccgcgatccgggcggaggccaaggac
gacacccagttcagcccggccgagggcgcgcccggcgacgttgccaaggtgctgctgtcg
gcggccaagtccggcctctccgccgtccacctggtggccggcgacccgttcgggcacgag
tccgtggtcaacgaggtgcaggcggtggcccgcaccgcggtgcacttcgaggtggtcccg
ggcatcggccaggccgagggcgtggcgacttacgccggcgtcccgctgccggccgtgcgc
acggcggccgacgtcgacgacgtgaccgcgctcgacttcgacgcgctggccgccgcggcc
ctcaagggctcgttcgcggtggcggtggacgcgggtgacctcgcggccgtccgcgacggt
ctgctcgcctcgggcgtcgagccgggcaccccggtcggcgtgaccggcgacggcaccggc
gagacccagtacaccaccacgtcgaccgtcgacagcttcgtggcggcggcgctcggcttc
accggccgcgtggtgctcaccgtcggcggcgacgtcgcggagcgcgacaagctgagctgg
tgggagaaccgcccgctgtacggctggaaggtgctcgtgccccggaccaaggagcaggcg
ggggcgatgagtgcccggctgcgcgcgtacggggcgatcccgtgcgaggtccccaccatc
gccgtcgagccgccgcgcacccccgcgcagatggaacgagcggtcaagggcctggtcgac
ggccgctacgcctgggtcgtcttcacctcggtcaacgcggtgcgggcggtctgggagaag
ttcggcgagcacggcctggacgcccggcacttcggtggcgtcaagatcgcctgcatcggt
gaggccaccgccgacgcggtccgcgcgttcggcatccagcccgagctcatcccggccgac
gaccagtccagcgagggcctgctggccgagttctcgccgcacgacgagatcctcgacccg
gtcggccgggtgctgctgccgcgggccgacatcgccaccgagacgctggccgcgggtctg
atcgagcgcggctgggaggtcgacgacgtcacggcctaccgcaccgtccgggccgccccg
ccgcccgccgacatccgcgacgccatcaaatccggtggcttcgacgcggtgctgttcacc
tcgtcctcgacggtgcgcaacctcgtcggcatcgcgggcaagccgcacgcccgcaccgtg
gtcgccgtgatcggccccaagaccgccgagacggccaccgagttcggcctgcgggtcgac
gtccagccgcagcacgcctccgttcccgacctggtcgaggcgctggcgtcgtacgcggtg
gagttgcgcgagaagctggccgccatgccggccaagcagcgccgcggctccaaggttcag
ggtccgacggccctgcgcttccgctga
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