Actinoplanes sp. NBRC 14428: Asp14428_53430
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Entry
Asp14428_53430 CDS
T08315
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
actr
Actinoplanes sp. NBRC 14428
Pathway
actr00860
Porphyrin metabolism
actr01100
Metabolic pathways
actr01110
Biosynthesis of secondary metabolites
actr01120
Microbial metabolism in diverse environments
actr01240
Biosynthesis of cofactors
Module
actr_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
actr_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
actr_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
actr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Asp14428_53430 (hemD)
Enzymes [BR:
actr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Asp14428_53430 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Asp14428_53430 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BCJ53868
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Position
5720999..5722585
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AA seq
528 aa
AA seq
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MTTRTARKSAGRIAFVGAGPGDPGLLTRRAHDTLADADQVVYDRGVPESLLAAIRAEAKD
DTQFSPAEGAPGDVAKVLLSAAKSGLSAVHLVAGDPFGHDSVVREVQAVARTAVHFEVVP
GLGQAEGVATYAGVPLPGVRTVADIDDVTAVDFDALAAAAQKGSFAVAVDAGDLAAVRDG
LLASGVEPGTAVGVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGAEVAERDKLSW
WENRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVD
GRYAWVVFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGEATADAVRAFGIQPELIPAG
DQSSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLIERGWEVDDVTAYRTVRAAP
PPADIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVD
VQPQHASVPDLVEALASYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgaccacccgcaccgcccgcaagagcgccggacgcatcgcgttcgtcggcgccggaccc
ggcgacccggggctgctgacgcgccgggcccacgacaccctcgccgacgccgaccaggtc
gtctacgaccgtggcgtccccgagtcgctgctcgcggcgatccgggcggaggccaaggac
gacacccagttcagcccggccgagggggctcccggcgacgtcgccaaggtgctgctctcc
gccgccaagtccggcctctccgccgtgcacctggtggccggcgacccgttcggccacgac
tccgtggtgcgcgaggtccaggccgtggcccgcaccgccgtgcacttcgaggtggtgccc
ggcctgggccaggccgagggcgtcgccacgtacgcgggtgtcccgctgcccggcgtccgc
acggtggccgacatcgacgacgtgacggcggtcgacttcgacgcgctcgccgcggcggcc
cagaagggctccttcgcggtggcggtggacgcgggcgacctcgccgcggtccgcgacggc
ctcctcgcctcgggcgtcgagccgggcaccgccgtcggcgtcaccggcgacggcaccggc
gagacccagtacacgaccacgtcgacggtcgacagcttcgtcgcggcggcgctcggcttc
accgggcgcgtggtgctcacggtcggtgcggaggtcgccgagcgcgacaagctgagctgg
tgggagaaccgcccgctgtacggctggaaggtcctcgtcccgcgcaccaaggagcaggcg
ggcgccatgagtgcccggctgcgggcgtacggggccatcccgtgcgaggtccccacgatc
gccgtcgagcccccgcgcaccccggcgcagatggagcgcgcggtcaagggcctggtcgac
ggccggtacgcctgggtcgtcttcacctcggtcaacgcggtccgcgcggtctgggagaag
ttcgcggagcacggcctcgacgcccgccacttcggcggcgtgaagatcgcctgcatcggc
gaggcgacggccgacgcggtccgcgcgttcggcatccagccggagctgatccccgccggc
gaccagtccagcgagggcctgctggcggaattctcgccgcacgacgagatcctcgacccg
gtcggccgggtgctgctgccgcgcgccgacatcgcgaccgagacgctggccgccggcctc
atcgagcgcggctgggaggtcgacgacgtgacggcgtaccgcacggtccgcgccgccccg
ccgccggccgacatccgcgacgcgatcaagtcgggtggcttcgacgccgtcctgttcacg
tcgtcctccacggtccgcaacctggtgggtatcgcgggtaagccgcacgcccgcacggtg
gtcgcggtgatcggccccaagacggccgagaccgcgacggagttcggcctgcgggtcgac
gtccagccgcagcacgcctcggtgcccgacctggtcgaggcgctcgcgtcctacgcggtc
gagctccgcgagaagctggccgcgatgccggccaagcagcgccggggctcgaaggtgcag
ggaccgacggcgctgcggttccgctag
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