Actinoplanes sp. NBRC 14428: Asp14428_61120
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Entry
Asp14428_61120 CDS
T08315
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
actr
Actinoplanes sp. NBRC 14428
Pathway
actr00290
Valine, leucine and isoleucine biosynthesis
actr00660
C5-Branched dibasic acid metabolism
actr01100
Metabolic pathways
actr01110
Biosynthesis of secondary metabolites
actr01210
2-Oxocarboxylic acid metabolism
actr01230
Biosynthesis of amino acids
Module
actr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
actr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Asp14428_61120 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Asp14428_61120 (leuC)
Enzymes [BR:
actr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Asp14428_61120 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
Asp14428_61120 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BCJ54637
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Position
6531696..6533141
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AA seq
481 aa
AA seq
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MVGVTPKPRTLAEKVWDDHVVRAAEGEPDLLYIDLHLLHEVTSPQAFDGLRLAGRPVRRT
DLTLATEDHNTPTGYADPAFNTRRGDLLTIADTTSRTQIETLRKNCAEFGVQIRSLGHEQ
QGIVHVIGPQLGLTQPGTTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLPQAKPK
TMAVTVVGELRPGVTAKDLILALITQVGTGGGNGHIVEYRGEAIRKLSMEGRMTICNMSI
EWGAKAGMIAPDETTFAYLKGREHAPKGADWDAAVEYWRSLVTDQDAEYDTEVILDASAI
SPFVTWGTNPGQGAALDSRVPDPEEFVDEVERNAARRALEYMGLEAGTPLKDVPVDVVFV
GSCTNGRLEDLRAAAEVIRGRKVHEGVRMMIVPGSYVVREQAEQEGLDKIFVDAGAEWRF
AGCSMCLGMNPDTLSPGQRAASTSNRNFEGRQGRGGRTHLVSPEVAAATAVAGKLAAPAD
L
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atggtgggagtcactccgaagccgaggaccctggccgagaaggtctgggacgaccacgtc
gtgcgtgctgccgagggtgagcctgatctgctctacatcgacctgcacctgctgcacgag
gtgaccagcccgcaggccttcgacggcctgcgcctggccggccgtccggtccggcgcacc
gatctcacgctcgcgaccgaggaccacaacacccctacggggtacgcggacccggcgttc
aacacccgccgcggcgacctcctcacgatcgcggacacgacctcgcgcacccagatcgag
acgctgcgcaagaactgcgccgagttcggcgtgcagatccgctcgctcggccatgagcag
cagggcatcgtccacgtgatcggcccgcagctcggtctcacccagccgggcacgaccatc
gtctgcggcgactcgcacaccgcgacccacggcgcgttcggcgcgctggccttcggcatc
ggcaccagcgaggtcgagcacgtcctcgccacccagacgctgccgcaggcgaagccgaag
acgatggcggtcacggtcgtcggcgagctgcgccccggcgtcaccgccaaggacctgatc
ctcgcgctgatcacccaggtcggcaccggcggcggcaacggccacatcgtcgagtaccgc
ggcgaggccatccgcaagctctccatggagggccggatgaccatctgcaacatgtccatc
gagtggggtgcgaaggccggcatgatcgcgccggacgagaccacgttcgcgtacctgaag
ggccgcgagcacgcgcccaagggtgccgactgggacgccgcggtggagtactggcggtcg
ctggtcaccgaccaggatgccgagtacgacaccgaggtgatcctggacgcctccgcgatc
agcccgttcgtcacgtggggcaccaacccgggtcagggcgcggcgctcgacagccgggtg
ccggatccggaggagttcgtcgacgaggtggagcgcaacgccgcccgccgcgcgctggag
tacatgggcctcgaggccggcacgccgctcaaggacgtaccggtggacgtggtgttcgtg
ggctcctgtaccaacgggcgcctcgaggacctgcgcgccgccgccgaggtgatccgcggg
cgcaaggtgcacgagggcgtccggatgatgatcgtgccgggctcgtacgtggtccgcgaa
caggccgagcaggagggcctcgacaagatcttcgtcgacgccggcgccgagtggcgtttc
gccggctgctcgatgtgcctgggcatgaacccggacacgctcagcccggggcagcgggcc
gcctccacgtccaaccgcaacttcgagggccggcagggccggggcgggcgtacccacctg
gtctcgcccgaggtcgccgccgccaccgccgtggccggcaagctggccgcccccgccgac
ctgtag
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