Actinomyces sp. 432: CWT12_03735
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Entry
CWT12_03735 CDS
T06433
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
actz
Actinomyces sp. 432
Pathway
actz00290
Valine, leucine and isoleucine biosynthesis
actz00660
C5-Branched dibasic acid metabolism
actz01100
Metabolic pathways
actz01110
Biosynthesis of secondary metabolites
actz01210
2-Oxocarboxylic acid metabolism
actz01230
Biosynthesis of amino acids
Module
actz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
actz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CWT12_03735 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CWT12_03735 (leuC)
Enzymes [BR:
actz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CWT12_03735 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CWT12_03735 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
QHO90625
UniProt:
A0A7L5AP01
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All DBs
Position
917425..918840
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AA seq
471 aa
AA seq
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MGMTLAQKVWRDHVVAPGTDGAPDLLYIDLHLVHEVTSPQAFEGLRLAGRKVRRPDLTMA
TEDHNTPTLDIDLPIADVTSRTQIETLRANCAEFGVRLHSLGDADQGIVHAVGPQLGLTQ
PGMTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPVAPFKTMSVLIDGDLPAGSG
AKDIILAIIAKIGTNGAQGHVIEYRGRAIEQLSMEARMTICNMSIEAGARAGMIAPDDTT
FAYLKGRPHAPEGEDWDAAVAYWRSLRTDDDAVFDTEVVLKGSDIEPFVTWGTNPGQGLP
ISGAVPDPEEIADETLRRAAERALEYMDLAPGTPLRDIKVDTVFLGSCTNGRIEDLRAAA
EVIKGRTKAPGLRMLVVPASARIRLQAEAEGLDEVFKEFGAEWRNAGCSMCLGMNPDQLA
PGERAASTSNRNFEGRQGKGGRTHLVSPVVAAATAVRGTLSTPADLPALAA
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgaccctggcacagaaggtgtggcgcgaccacgtcgtcgcccccggcaccgac
ggagccccggacctgctctacatcgacctgcacctcgtccacgaggtcaccagcccgcag
gcgttcgagggcctgcgcctggccggccgcaaggtccgccgtcccgacctgaccatggcc
accgaggaccacaacacccccaccctggacatcgacctgcccatcgccgacgtcacctcc
cgcacccagattgagaccctgcgcgccaactgcgccgaattcggggtgcggctgcactcc
ctgggcgacgcggaccagggcatcgtccacgccgtcggcccgcagctggggctcacccag
cccggcatgaccgtggtgtgtggtgactcccacacctccacccacggcgccttcggggcg
ctcgccttcggcatcggcaccagccaggtcgagcacgtgctggccacccagaccctgccc
gtggcccccttcaagaccatgagcgtgctcatcgacggtgacctgcccgccggcagcggc
gccaaggacatcatcctggccatcatcgccaagatcggcactaatggcgcccaggggcac
gtcatcgagtaccgcggccgcgccatcgagcaactgtcgatggaggcccgcatgaccatc
tgcaacatgagcatcgaggccggtgcccgcgccggcatgatcgcccccgacgacaccacc
ttcgcctacctcaagggccgcccgcacgcccccgagggggaggactgggacgccgccgtc
gcctactggcgctccctgcgcaccgatgacgacgccgtcttcgacaccgaggtcgtcctg
aagggcagcgacatcgagcctttcgtcacgtggggcaccaaccccggtcagggcctgccc
atctccggggcggtaccggaccccgaggagatcgcggacgagacgctgcgtcgtgctgcc
gagcgcgccctggagtacatggacctggcgcccggcaccccgctgcgcgacatcaaggtg
gacacggtcttcctcggttcatgcaccaatgggcgtatcgaggacctgcgcgccgccgcc
gaagtcatcaagggccgcaccaaggcgcccggcctgcgcatgctcgtggtgccggcctcc
gcccgtatccggctgcaggccgaggccgaggggctggatgaggtgttcaaggagttcgga
gccgagtggcgcaatgccggctgctccatgtgcctgggaatgaaccccgatcagctggcc
cccggtgagcgtgccgcctccacctctaaccgcaacttcgagggccgccagggcaagggc
gggcgcacccacctggtctcgcccgtagtcgccgccgccaccgcggtgcgcggaaccctg
tccactcccgcggacctgccggcgctcgccgcctga
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