Amycolatopsis cynarae: ORV05_25380
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Entry
ORV05_25380 CDS
T09969
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
acyn
Amycolatopsis cynarae
Pathway
acyn00290
Valine, leucine and isoleucine biosynthesis
acyn00660
C5-Branched dibasic acid metabolism
acyn01100
Metabolic pathways
acyn01110
Biosynthesis of secondary metabolites
acyn01210
2-Oxocarboxylic acid metabolism
acyn01230
Biosynthesis of amino acids
Module
acyn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
acyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ORV05_25380 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ORV05_25380 (leuC)
Enzymes [BR:
acyn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ORV05_25380 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ORV05_25380 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
WAL64285
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All DBs
Position
complement(5312642..5314078)
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AA seq
478 aa
AA seq
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MSETRPRTLAEKVWDAHTVRRGEGAEPDLLYIDLHLVHEVTSPQAFDGLRLAGRGFRRTD
LTIATEDHNVPTVDIELPIADPVSRTQVETLRRNCKEFGVRLHPMGDAEQGIVHVIGPQL
GLTQPGMTVVCGDSHTSTHGAFGAMAFGIGTSEVEHVMATQTLPLRPFKTMAINVNGKLR
PGVTAKDIILAVIARIGTGGGQGYVLEYRGSAIEALSMEARMTVCNMSIEAGARAGMIAP
DETTFAYLKDRPHAPKGADWDAAVAYWRQLRTDEGAEFDAEVDLDADELTPFVTWGTNPG
QGLPLSASVPDPEAIADENERLAAEKALSYMDLEPGTPLRDIRVDTVFLGSCTNGRLEDL
RAAADVLRGRKVAEGVRMLVVPGSMRVRQAAEAEGLDRIFADAGAEWRQAGCSMCLGMNP
DQLKPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLQPATTASN
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atgtccgagacacggcctcgcacactggccgagaaggtgtgggacgcgcacacggtgcgc
cgcggcgaaggcgccgagcccgatctgctctacatcgacctgcacctggtgcacgaagtc
accagcccccaggcgttcgacggcctgcggctggcgggccgcgggttccgcaggacggat
ctcaccatcgccaccgaagaccacaacgtccccaccgtcgacatcgaactgccgatcgcc
gacccggtgtcccgcacccaggtggagacccttcgccgcaactgcaaggagttcggcgtc
cggctgcacccgatgggcgacgcggaacagggcatcgtgcacgtcatcggcccgcagctc
ggcctcacccagcccggcatgaccgtggtgtgcggcgacagccacacctccacccacggc
gccttcggggccatggccttcggcatcggcacctccgaggtggaacacgtgatggccacc
cagaccctgccgctgcgtccattcaagacgatggcgatcaacgtcaacggcaagctgcgc
cccggcgtgaccgccaaggacatcatcctcgccgtgatcgccaggatcggcaccggcggc
ggccagggctacgtgctggagtaccgcggcagcgcgatcgaggcactgtccatggaagcc
cgcatgaccgtgtgcaacatgtcgatcgaggcgggcgcccgggccgggatgatcgccccc
gacgagaccaccttcgcctacctcaaggaccgcccgcacgcgccgaagggtgccgactgg
gacgccgcggtggcctactggcggcagctgcgcaccgacgagggtgccgagttcgacgcc
gaggtggacctcgacgccgacgagctgaccccgttcgtcacctggggcaccaaccccggg
cagggcctgccgctgtcggcctcggtccccgaccccgaggccatcgccgacgagaacgag
cgcctggccgccgagaaggccctgtcctacatggatctggagccgggcaccccgctgcgc
gacatccgcgtggacaccgtgttcctcggttcctgcaccaatggccgcctggaggacctg
cgggccgccgcggacgtcctgcggggccgcaaggtcgccgagggggtgcggatgctcgtg
gtgccgggctcgatgcgggtgcggcaggccgcggaggccgagggactggacaggatcttc
gccgacgccggggccgagtggcgtcaggcgggatgctccatgtgcctgggcatgaacccc
gatcagctcaagcccggcgagcgcagcgcgtccacctccaaccgcaacttcgagggcagg
cagggcaagggcggccgcacccacctggtgtccccgctggtggccgccgccaccgcggtc
cgcggcacgctgtcctccccggaggacctgcagcccgccaccaccgcgtcgaactga
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