KEGG   Anoxybacillus flavithermus: Aflv_0596
Entry
Aflv_0596         CDS       T00790                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
afl  Anoxybacillus flavithermus
Pathway
afl00290  Valine, leucine and isoleucine biosynthesis
afl00660  C5-Branched dibasic acid metabolism
afl01100  Metabolic pathways
afl01110  Biosynthesis of secondary metabolites
afl01210  2-Oxocarboxylic acid metabolism
afl01230  Biosynthesis of amino acids
Module
afl_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:afl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    Aflv_0596 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Aflv_0596 (leuC)
Enzymes [BR:afl01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     Aflv_0596 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     Aflv_0596 (leuC)
SSDB
Motif
Pfam: Aconitase AcnX
Other DBs
NCBI-ProteinID: ACJ32977
UniProt: B7GH21
LinkDB
Position
641401..642816
AA seq 471 aa
MVPKTIIEKIWDEHVVYREDGKPDLLYIDLHLVHEVTSPQAFEGLRQKGRKVRRPDLTFA
TMDHNVPTINRSVVEDEVAKNQMTALERNCREFGVPLADLNSPEQGIVHVIGPELGLTQP
GKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLWQHRPKTMQVNVTGSLAPGVSA
KDVILAIIGKFGVDFGTGYVLEFTGDVIRRMSMEERMTICNMSIEAGARAGLIAPDDVTF
AYLKERKYAPKGEAFEQAVEKWKQLCTDEGAVYDRVVHIDGSEIAPTVTWGTTPAMSSPI
DGTVPDPNEFATETERKAVQLALQYMGLKPGTKMTDIAVQHVFIGSCTNSRISDLREAAQ
IVKGKKVAPGVRALVVPGSQQVKKQAEEEGIAQTFIDAGFEWRDSGCSMCLGMNPDTVPA
GEHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAIYGHFVDVRTLYKEVVR
NT seq 1416 nt   +upstreamnt  +downstreamnt
gtggtgccaaagacgattattgaaaaaatttgggatgaacacgtggtttaccgtgaagat
gggaaacccgatttattatatattgatttacatctcgttcatgaagtgacatcgccgcaa
gcttttgaaggattgcgacaaaaaggaagaaaagtgcgtcgcccagatttaacatttgcg
acgatggaccataacgttccaacgattaatcggtccgttgttgaagatgaagtggcgaaa
aatcaaatgacagcattggagcggaactgtcgtgagttcggtgttccgcttgccgattta
aacagtccagaacaagggattgttcatgtcatcggtccagaactcgggttgacacagcct
gggaaaaccattgtgtgtggagatagccatacgtctacacatggcgcttttggggcatta
gcgttcgggatcggaacgagtgaagtcgaacacgtattagcgacgcaaacgttatggcaa
catcgtccaaagacgatgcaagtgaacgttacgggatcgttagcaccgggcgtatcagca
aaagacgttattttagcgatcattggcaagtttggagttgattttggcacaggctacgtg
cttgagtttacaggcgatgttattcgtcgtatgtcaatggaagagcggatgacaatttgc
aatatgtcgattgaagcaggggcacgagctgggttaattgccccagatgatgtgacgttt
gcatatttaaaagagagaaaatatgcaccgaaaggagaagcgtttgagcaggcagttgaa
aagtggaagcagttatgcacagatgaaggagcggtatacgatcgtgtcgttcatattgat
ggaagtgaaattgctccaacagtgacatggggcacaacgccagcaatgagctctccgatc
gatggaactgttccagatccgaacgagtttgcgacagaaacagagagaaaagctgtacag
ttagcgttgcaatatatgggattaaagccaggaacgaaaatgacggatattgcggtgcaa
catgtgtttatcggatcatgcacaaactcgcgcataagcgatttacgggaagcggcgcaa
attgtaaaaggaaaaaaagtcgcaccgggcgtcagagcgctcgtcgttccgggctcacaa
caagtaaaaaagcaggcagaagaagaaggaattgctcaaacgtttattgacgcaggcttt
gaatggcgcgattccggctgtagcatgtgtcttggaatgaatccagatactgttccagca
ggggaacattgcgcctcaacgtcaaaccgcaatttcgaagggagacaaggaaaaggggcg
cgcacgcatctcgtgagtccagcaatggcagccgcggctgcgatttacgggcattttgtc
gatgtgcgtacattgtataaagaagtggtaagatag

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