Aspergillus fumigatus: AFUA_1G14570
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Entry
AFUA_1G14570 CDS
T01017
Name
(RefSeq) phosphoribosyl-AMP cyclohydrolase
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
afm
Aspergillus fumigatus
Pathway
afm00340
Histidine metabolism
afm01100
Metabolic pathways
afm01110
Biosynthesis of secondary metabolites
afm01230
Biosynthesis of amino acids
Module
afm_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
afm00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
AFUA_1G14570
Enzymes [BR:
afm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
AFUA_1G14570
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
AFUA_1G14570
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
AFUA_1G14570
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Gene cluster
GFIT
Motif
Pfam:
Histidinol_dh
PRA-CH
PRA-PH
MazG
Motif
Other DBs
NCBI-GeneID:
3509848
NCBI-ProteinID:
XP_752826
UniProt:
Q4WRZ4
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Position
1:3892553..3895217
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AA seq
872 aa
AA seq
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MATPILISYNPTSASSGLSLSQIAYFGRVLIKVSSLSQAEEFLRQNFRLLDVYVDATDIT
SSGDIVDILNAGAAKAFISLDQLTSLSQEQSVPSSRLVVYTSSDSQVDAFQSWVGEDAER
KEAGICTESADVKTVADRLGLNLEAQNLYRTYTTSTVTEDAVKETLKQGAVSIVSADALT
LDHKNPSGKIAAAALVAARAVADQSNGLYATSVTDERGVCLGLVWSSDESIAEALRTGTG
VYQSRKRGLWYKGQSSGDVQELIRLGFDCDSDCLVFVVKQIGRGFCHLGTASCFGPYNGL
ARLQKTLQARKADAPAGSYTARLFNEPKLTQAKIMEEADELCRATTKEEIAFEAADLLYF
ALTRCVAAGVSLEDIERNLDLKSLKVKRRKGDAKGPWAEKAGLTASPAETKPAGPAAPAK
EAAKKDDSRMEMTRVVTASTPVDKVKEYLKRPSQKSNDAIVGLVRPIIQDVRDGGDAAVL
KYTHKFEKATSLTSPVIRAPFPPELMKLSPETQEAIDVSIANIKKFHSAQKDSNDVLQVE
TMPGVVCSRFSRPIERVGLYVPGGTAVLPSTAMMLGVPAMVAGCQKIVLASPPRADGSIS
PEIVYVAHKVGAESIVLAGGAQAVAAMAYGTESISKVDKILGPGNQFVTAAKMLVSNDTS
AGVSIDMPAGPSEVLVIADKDANPAFVASDLLSQAEHGVDSQVILIAIDLNESQLQAIED
EVDAQARALPRMDIVRGSLAHSVTFVVRDIDEAMALSNEYAPEHLILQVKNAESVVEKVV
NAGSVFIGQWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLGSFLKHITSSNLTAEGLLGL
SRTVEQLAAVEGLDAHKRAVSIRVAAMKKNQA
NT seq
2619 nt
NT seq
+upstream
nt +downstream
nt
atggctaccccaatcctcatctcctacaaccccacctctgcctcctccggtctctccctc
tcccagatcgcctatttcggccgcgtcctcatcaaggtctcctctctcagtcaagctgag
gagtttctgcgtcagaatttccgtctcctcgatgtctacgtcgacgctaccgacatcact
tcctctggtgacattgtcgatatcctaaatgccggtgccgccaaagcattcatttccctc
gatcaattgacctcgctgtcccaagagcaatccgttccgtcgtcgcgactcgtcgtttat
acctcctccgacagtcaggttgatgcctttcagtcgtgggttggcgaggatgctgaaaga
aaggaagccggaatatgcaccgagtctgccgacgtcaagaccgtggccgacagattgggc
ttgaatcttgaggctcagaacctttaccgcacctacaccaccagcacagttaccgaggac
gctgtgaaggaaacattgaagcagggtgccgtcagcattgtctcggccgacgccctcacc
ctcgatcacaaaaatcccagcggcaagatcgccgccgccgcactggttgccgctcgtgct
gttgcggaccagagcaacggcctgtacgcgacttcggtgactgatgagcggggagtatgt
ctgggccttgtctggagcagcgacgaaagtatcgccgaggctctccgcactggcaccggt
gtctaccagagccgcaaacggggtctgtggtacaagggtcagtccagcggtgacgtgcag
gagctgattcgcctgggctttgactgcgacagcgactgcctggtctttgtggtcaagcag
attggccgcggcttctgtcacttgggtaccgccagctgcttcggaccttacaatggcctt
gcgcgtctgcaaaagacccttcaggcccgcaaagccgatgcaccggccggttcctacacc
gctagattgttcaacgagcccaagctgacccaggcaaagatcatggaggaggccgacgag
ctgtgccgtgccaccaccaaggaggagatcgcgtttgaggctgccgatctactctacttt
gccctgactcgctgcgtggccgcaggagtcagcttggaagatattgaacgtaacttggat
ctgaagagtctcaaggtcaagagaagaaagggcgatgcgaaggggccgtgggcggagaag
gctggtctgactgctagccctgccgaaacgaagcccgccggtcccgcagctccagccaag
gaagcggccaagaaggatgactctcgcatggagatgacccgcgtggtcaccgcctccacc
cctgtagacaaggtcaaggagtacctcaagcgtccttctcaaaagtccaacgacgccatc
gtgggcctcgttcgccccatcatccaggatgtgcgggacggcggtgatgctgctgtgctc
aagtatactcacaagtttgaaaaggcgacttctctgacgtctcccgtaatccgcgctccc
ttcccccccgagctgatgaagttgtcgcctgagacccaggaagccatcgatgtcagcatt
gccaatatcaagaagtttcactccgcccagaaggacagcaatgacgtcctccaggtggag
acgatgcctggagtcgtttgctcgcgcttttctcgccctattgagcgtgttggtctgtac
gtccccggtggcacagccgtgctgccgtccaccgccatgatgctcggtgtccccgccatg
gttgccggctgccagaagattgtcttggcttctcctcctcgggccgatggcagcatctcc
cccgagattgtctacgtcgcccacaaagtgggagccgagagcattgtcctcgccggtggt
gcgcaggccgtggccgccatggcttacggaacggagagtatcagcaaggtggacaagatc
ttgggccccggtaaccagttcgtgacggcagccaagatgctggtttccaacgacacctcg
gccggtgtcagcatcgatatgcccgccggacctagtgaggtgttggtcatcgccgacaag
gacgccaacccggccttcgtggcttcggatctgctgagccaggctgagcacggcgttgac
tcgcaggtgatcctgatcgccatcgacttgaacgagagccaactgcaggccatcgaggac
gaggtcgatgcccaggcccgggccctgccccggatggacattgtccgaggatctctagca
cactcggtcaccttcgtggtgcgtgacattgatgaggcgatggcgctcagcaatgaatat
gcgccggagcatctgattcttcaggtgaagaacgcggagtcggtagtggagaaggtcgtc
aacgccggcagcgtcttcatcggacagtggacccctgagagtgttggtgattactctgcg
ggtgtcaaccactctttgccaacctacggctacgccaagcagtactctggagtcaacctg
ggctcgttcctcaagcacatcaccagctcgaacttgacggcagagggattgctgggattg
tctcgcacggtggagcagttggctgccgttgagggattggacgcgcacaagcgggccgtg
agcatccgagtcgcggcgatgaagaagaaccaggcgtga
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