Acidimicrobium ferrooxidans: Afer_0251
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Entry
Afer_0251 CDS
T00956
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
afo
Acidimicrobium ferrooxidans
Pathway
afo00860
Porphyrin metabolism
afo01100
Metabolic pathways
afo01110
Biosynthesis of secondary metabolites
afo01120
Microbial metabolism in diverse environments
afo01240
Biosynthesis of cofactors
Module
afo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
afo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Afer_0251
Enzymes [BR:
afo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Afer_0251
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Afer_0251
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ACU53220
UniProt:
C7M2H6
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All DBs
Position
255890..257362
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AA seq
490 aa
AA seq
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MGRVALVGAGPGDPELLTLRGLRLVRAADVVVTDALVDRRVLAEVRPAVAVHDVGKRAGA
PFSQAAINELLIDLARGHELVVRLKGGDPFLFGRGGEELEALLAAGVAVEVVPGVPSATA
AADLVGVPLTHRGVADGFCVITGHRHGDASLDYDWRALVASGLTLVVLMGAASRATIAKE
LMGAGAPGETPVAVVTRASWIDEEVRWTSLAALGSVPVASPSTIIIGGVVDPRRRWRPSL
PLGGLRIVVTRPRAVADALAVRLRDLGAVVVASPAIEIGPPSDGGAALAAALSHIEDYDW
LVLTSQNAVDRVVGGIGDLRRLGGVRIAAIGPATARALERVHLTADLIPGTWVGEGLVEV
FGPGPGSVLIARARQARDVVPRGLEAKGWRVDVVEAYETRTAAASVPPELVESADLVVFT
APSTVEGFATQYPGLVPRAAAAIGPVTEEALVRRGWPVALTATHYDADGLVEVIREAREA
GRLVPRSEAP
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgggacgcgttgcgctcgtcggtgccggccctggcgacccagagctcctcacgctccgc
ggtctgaggctcgtgcgtgcggccgacgtcgtcgtcaccgacgctctcgttgatcgacgt
gtgcttgccgaggtgcggccggcggtcgcggtgcacgacgtcggcaagcgtgctggagca
cccttctcgcaggctgccatcaacgaactcctgatcgacctcgcccgcggccatgagctc
gtcgtgcggctgaagggcggcgacccgttcttgttcggtcgcggcggagaggagctcgag
gcgctgctggcagcgggggtcgccgtcgaggtggtccctggcgtgccgagtgcgacggcc
gcggcggacctcgtcggtgtcccgctcacccatcggggcgtggcggacggcttctgtgtg
atcaccggtcatcgccacggcgacgcgtcgctcgactacgactggcgtgcactcgtcgcg
agtgggctcacgctcgtcgtgctcatgggggccgcttctcgtgcgaccatcgccaaggag
ctgatgggcgccggagctcctggtgagaccccggtcgcggtcgtgacacgcgcatcgtgg
atcgatgaagaggtccgctggacgagcctcgcggcgctcgggtcggtgcctgtcgcgtct
ccgagcacgatcatcatcggcggcgtggtcgatccgcggcgccgatggcgaccctcgctg
ccgctcggtggcctccgtatcgtggtgacacgcccgagagcggtcgcagatgcgctcgcg
gtgcgcctccgcgatctcggtgccgtcgtcgtggcgagcccggcgatcgagatcggtccg
ccgtcggatggcggtgccgcactggccgcggcgctctcgcacatcgaggactacgactgg
ctcgtcctcacctcgcagaacgccgtcgatcgcgtcgtaggaggcatcggcgaccttcgg
cgtctcggtggcgtgcgcatcgcggccattggccccgcgaccgctcgggcgctcgagcgg
gtccacctcacggccgatctcatccccgggacgtgggttggggaggggctggtcgaggtg
ttcggccctggtcctggctcggtgctcatcgccagggcacgccaggcccgcgacgtcgtg
ccacggggcctcgaggcgaaggggtggcgcgtcgacgtcgtcgaggcgtacgagacgcgc
acagcagcggcgagcgtgcctccagagctcgtcgagagcgccgatctcgtcgtgttcacg
gcaccgtccaccgtcgagggtttcgcgacccagtacccggggctcgtccctcgggccgcg
gcggcgatcgggcccgtcaccgaggaggcgctggtgcggcgagggtggccggtcgcgctg
accgcgacgcactacgacgccgatggcctcgtggaggtgattcgcgaggcgcgcgaagcg
ggtcggctcgtgcctcgatccgaggcgccctag
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