Acidithiobacillus ferrooxidans ATCC 23270: AFE_0624
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Entry
AFE_0624 CDS
T00810
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
afr
Acidithiobacillus ferrooxidans ATCC 23270
Pathway
afr00290
Valine, leucine and isoleucine biosynthesis
afr00660
C5-Branched dibasic acid metabolism
afr01100
Metabolic pathways
afr01110
Biosynthesis of secondary metabolites
afr01210
2-Oxocarboxylic acid metabolism
afr01230
Biosynthesis of amino acids
Module
afr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
afr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AFE_0624 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AFE_0624 (leuC)
Enzymes [BR:
afr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
AFE_0624 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
AFE_0624 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ACK79183
UniProt:
B7J5E0
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All DBs
Position
556828..558240
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AA seq
470 aa
AA seq
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MSAKTLYDKLWESHVVHTEQDGGVLLYIDRQLLHEVTSPQAFSGLRAAGRKAWRIDANIA
TADHNVPTTDRAAGIADATSRLQVDTLDRNCAEFGIEEFGMHDKRQGIVHVIAPEQGLTL
PGMTVVCGDSHTATHGALGALAFGIGTTEVEHVLATQCLWARKSRSMRIWVEGELGNGVT
AKDLVLAIIGRIGTAGGTGYAIEFAGPAVHALSVEGRMTLCNMAIEAGARSGMVGVDAVT
IDYLRGRPYAPVGKIWDQAVAVWGELHSDPDAQFDAEIRLEATDVAPQVTWGTSPEMVVD
ISARVPDPALEKDPVRRKGWSDALAYMDLAAATPISSIALDKVFIGSCTNARIEDLRAAA
AVARGHHKAASVKAVLVVPGSGLVKAQAEAEGLDRIFRDAGFEWREPGCSMCLAMNADRL
EPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAIAGHFVDVRDWIMH
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
gtgtctgcaaaaacgctctacgataaattatgggaaagccatgtggtccatacggagcag
gacggcggagtgttgctctatatcgaccgtcaattgttgcacgaagtgaccagcccgcag
gccttttccgggctgcgggcggcgggccgcaaggcgtggcgcattgatgccaatatcgca
acggccgaccacaacgtgccgaccactgatcgcgccgcagggattgccgacgccacctcg
cgcttgcaggtggataccctcgaccggaactgtgcggagtttggcatcgaagaatttggt
atgcacgataagcgtcagggcattgttcacgtcattgcaccggaacagggcctgaccctg
ccgggcatgacggtggtctgtggcgactcccacacggcgacccatggggcgttgggggcg
ctggccttcgggatcggcaccaccgaagtggagcacgtgctggcgacccagtgcctgtgg
gcgcgcaaatccagatccatgcgcatctgggtggagggtgagctgggcaatggggtgacc
gcgaaagatctggtgctggccatcatcgggcgaatcggcacggcgggtggcactggctac
gccatcgagtttgccggacctgcggtgcatgcgctgtcggttgaaggccgtatgaccctg
tgcaatatggccattgaagcgggtgcgcgctcgggcatggtgggtgtggatgccgtcacc
atcgattatctccgtggccgcccctatgccccggtcggcaagatctgggatcaggcggtt
gcggtctggggcgaactccacagcgaccctgatgcgcagtttgacgcagagattcgtctg
gaggccacggatgtggccccccaggtcacctggggcaccagcccggagatggtggtggat
atttctgcgcgggtccccgatcctgcactggaaaaggacccggtgcggcgcaagggctgg
agtgatgcactggcttacatggatctggcggccgcaacacccatttcttcgatagcgctg
gacaaggtattcatcggctcctgcaccaatgcccgcattgaagacttgcgggcggcggcg
gcggttgccagaggccatcacaaggctgcgtcggtcaaggcggtgctggtagtgccgggc
tccggtctggtcaaggcgcaggcggaagccgaaggcctggaccgcatcttccgggatgcc
ggttttgaatggcgggagccaggctgctccatgtgtctggccatgaacgccgaccgcctg
gagccgggggagcgttgcgcgagcaccagtaatcgcaattttgaagggcgtcagggcgct
ggaggacggacccacctggtgagccccgccatggccgcagcggctgccattgccggccat
tttgtggatgtgcgtgactggatcatgcactaa
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