Actinomyces marmotae: HPC72_07280
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Entry
HPC72_07280 CDS
T07249
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
amam
Actinomyces marmotae
Pathway
amam00790
Folate biosynthesis
amam01100
Metabolic pathways
amam01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
amam00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HPC72_07280
Enzymes [BR:
amam01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HPC72_07280
6.3.2.17 tetrahydrofolate synthase
HPC72_07280
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QKD80046
UniProt:
A0A6M8B7J2
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All DBs
Position
complement(1727784..1729715)
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AA seq
643 aa
AA seq
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MTHHQGPGSAASAGGRPGSEGGAPSHPGAAFGIPAHATPEEAVDAVFGGGARDGGEGIDP
ALLPYLEAADAPAAGSSGSAAAGLSLAEARQARGERAEARLAAEAEDLAALRELVAHNML
ASGDPDELDALLAEVDADDSDDWESWEPVLPGTGDDPDGDQDEPAREGGPGDGDAHRRAL
LAAARGVEVGERMRQVEAEILSRAPEHRVQPSLERIEAVMDILGHPERAYRVIHITGTNG
KTSTARMTERLLAAAGLRTGRFTSPHLATIRERISLDGEPISEEGFIAAWEDVAPYIAMV
DERSLADGGPRMSFFEVLTVMALAAFADHPVDAAVIEVGMGGTWDCTNVVDSDVEVITPI
GLDHAAWLGSTIREVAQNKAGIIKDGATLITSVQVPQAQEVIAAAAAEHRVVWRRELDPD
EDPGEPGAGELSVRSRELAVGGQLVTLATAAAVYEDVFVPLHGEYQAHNALLALAAAEAF
FGGRALPPALVEEGFSSTTSPGRLEVLRSSPTVIVDAGHNPHGVAALMPAIEEAFGFKHL
VAVVGAMEDKDVEGILSILEPACDAVVCVPIDSPRAMDVEDLGAVAREVFGQDRVQVARA
LADGVDRAVALSEGGDGPLTAAGVLIVGSVVLAAEARALFRRP
NT seq
1932 nt
NT seq
+upstream
nt +downstream
nt
atgacccaccaccagggacccgggtccgcggcgagcgctgggggccggcccggcagcgag
ggtggggcgccctcccacccgggcgcggctttcggcatccccgcccatgccacccccgag
gaggccgtcgacgccgttttcggcggtggcgccagggatgggggagaggggatcgacccg
gcgctcctgccctacctcgaggccgccgacgcccccgcggccgggtcgtcgggctccgcg
gccgcgggcctcagcctcgccgaggcccgccaggcccgcggggagagggccgaggcgcga
ttagcggccgaggccgaggacctggcggccctgcgcgagctcgtcgcccacaacatgctg
gcctcgggcgacccggacgagctcgacgcgctcctggccgaggtcgacgccgacgactcc
gatgactgggagtcctgggaacccgtcctgcccggcactggcgacgatcccgacggtgat
caggacgaaccggcgcgcgagggcggtcccggcgacggggacgcccaccgccgggccctg
ctggcggccgcccgcggcgtcgaggtgggcgagcgcatgcggcaggtcgaggccgagatc
ctctcccgcgcccccgagcaccgcgtccagccctccctggagcgcatcgaggcggtcatg
gacatcctgggccaccccgagcgcgcctaccgggtcatccacatcaccggcaccaacggc
aagacctcgaccgcccgcatgaccgagcggctgctggcggccgcgggcctgcgcaccggc
cgattcaccagcccgcacctggccacgatccgcgagcgcatcagcctggacggcgagccc
atcagcgaggagggcttcatcgccgcatgggaggacgtcgccccctacatcgcgatggtc
gatgagcgttccctggccgatggcggcccgaggatgagcttcttcgaggtcctcaccgtc
atggcgctggcggccttcgccgaccatcccgtggacgctgccgtcatcgaggtcggcatg
ggcggcacctgggactgcacgaatgtcgtggactccgatgtcgaggtcatcacccccatc
ggattggaccacgccgcctggctcgggagcacgatccgcgaggtcgcccagaacaaggcg
ggcatcatcaaggacggggccaccctcatcacctcggtccaagtgccccaggcgcaggag
gtgatcgccgcggcggcggctgagcaccgggtcgtgtggcgcagggagctcgatcccgat
gaggaccccggcgagccgggcgccggggagttgagcgtgcgctcgcgcgaactggccgtg
ggcggccagctcgtcacgctggccacggcggccgccgtctacgaggatgtcttcgtgccc
ctccatggcgagtaccaggcgcataacgcgctgctggcgctcgcggcggccgaggccttc
ttcggggggcgcgccctcccaccggccctcgtggaggagggcttttcctcgacgacctcc
ccggggcgcctggaggtcctgcgctcctccccgaccgtcatcgtcgatgccgggcacaac
ccgcacggcgtggccgcgctcatgcccgccatcgaggaggccttcggcttcaagcatctc
gtcgccgtcgtgggcgccatggaggacaaggacgtcgagggcatcctgtcgatcctcgag
cccgcctgcgacgccgtcgtctgcgtgcccatcgactccccccgagccatggacgtcgag
gacctgggagccgtcgcccgtgaggtcttcgggcaggaccgcgtccaggtggcgcgggcc
ctggccgacggggtcgaccgcgccgtcgcgctctccgagggcggggacgggccgctgacc
gccgcaggcgtgctgatcgtgggctcggtggtcctggccgccgaggcgcgggccctgttc
cgccgcccctga
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