Actinomadura madurae: LUW76_39070
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Entry
LUW76_39070 CDS
T08933
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00290
Valine, leucine and isoleucine biosynthesis
amaz00660
C5-Branched dibasic acid metabolism
amaz01100
Metabolic pathways
amaz01110
Biosynthesis of secondary metabolites
amaz01210
2-Oxocarboxylic acid metabolism
amaz01230
Biosynthesis of amino acids
Module
amaz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
LUW76_39070 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LUW76_39070 (leuC)
Enzymes [BR:
amaz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
LUW76_39070 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
LUW76_39070 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Se_S_carrier
Motif
Other DBs
NCBI-ProteinID:
URM99841
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All DBs
Position
8218069..8219466
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AA seq
465 aa
AA seq
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MGRTLAEKVYDAHVVRRAEGEPDLLYIDLHLVHEVTSPQAFDGLRMAGRQVRRPDLTIAT
EDHNVPTTDLLKPIADPVSRTQVETLRKNCSDFGIRLHPMGDDGQGIVHVIGPQLGLTQP
GMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPQIQPKTMAVTVNGALPEGVTA
KDLILAIIARIGTGGGQGHIIEYRGEAVRSLSMEGRMTVCNMSIEAGARAGMIAPDETTF
EYLKGRPHAPSGEDWDRAVEYWTSLRTDDDAVFDKEVVIDASELTPFVTWGTNPGQGLPL
AESVPDPASIDDPVKRQNAERALEYMGLTAGTRLRDIEVDTVFVGSCTNGRIEDLRAVAG
VLKGRRVADGVRMLVVPGSMKVKRQAEEEGLDAVISASGAEWREAGCSMCLAMNPDKLTP
GERSASTSNRNFEGRQGPGGRTHLVSPAVAAATAVTGRLTAPADL
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgggccgaacactggccgagaaggtgtacgacgcgcacgtcgtacggcgagccgagggt
gagccggacctcctctacatcgacctgcacctggtccacgaggtcaccagcccgcaggcg
ttcgacgggctgcggatggccggccgccaggtccgccgccccgacctcacgatcgccacc
gaggaccacaacgtcccgaccacggacctgctcaagccgatcgccgacccggtgtcgcgc
acccaggtcgagacgctccgcaagaactgctccgacttcgggatccggctgcacccgatg
ggcgacgacggccagggcatcgtgcacgtcatcggcccgcagctcggcctcacccagccc
ggcatgaccgtcgtgtgcggcgactcgcacacctccacgcacggcgcgttcggcgcgctc
gccttcggcatcggcaccagcgaggtcgagcacgtcctcgccacccagacgctgccgcag
atccagccgaagacgatggccgtgaccgtgaacggcgcgctgcccgagggcgtcaccgcc
aaggacctcatcctggcgatcatcgcgcggatcggcaccggcggcggtcagggccacatc
atcgagtaccgcggcgaggccgtccggtcgctgtcgatggaaggccgcatgacggtctgc
aacatgtccatcgaggccggcgcccgcgccgggatgatcgctccggacgagaccacgttc
gaatacctcaaggggcgtccacacgcgccgtccggcgaggactgggaccgggccgtcgag
tactggacgtccctgcgcaccgacgacgacgcggtcttcgacaaggaggtcgtgatcgac
gcgtccgagctgaccccgttcgtcacgtggggcaccaacccgggccaggggctgccgctc
gccgagtccgtcccggacccggcgtccatcgacgacccggtcaagcggcagaacgccgag
cgggcgctggagtacatgggcctcaccgccgggacgcggctgcgcgacatcgaggtcgac
accgtcttcgtcggctcctgcaccaacggccgcatcgaggacctgcgcgccgtcgctggc
gtcctcaagggccgcagggtcgccgacggcgtccggatgctcgtcgtccccggctcgatg
aaggtcaagaggcaggccgaggaggagggcctcgacgcggtcatctccgcgtccggcgcc
gagtggcgcgaggcgggctgctcgatgtgcctggcgatgaaccccgacaagctcacgccc
ggcgagcgcagcgcctccacgtccaaccgcaacttcgagggccggcagggacccggcggc
cgcacccacctggtgtcgcccgccgtcgccgccgccaccgccgtcaccggccgcctgacc
gctcccgccgacctgtaa
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