Amycolatopsis mediterranei U32: AMED_0482 Help Entry AMED_0482         CDS       T01269                                  Symbol hemD Name (GenBank) uroporphyrinogen-III synthase   KO K13542   uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75] Organism amd  Amycolatopsis mediterranei U32 Pathway amd00860   Porphyrin metabolism amd01100   Metabolic pathways amd01110   Biosynthesis of secondary metabolites amd01120   Microbial metabolism in diverse environments amd01240   Biosynthesis of cofactors Module amd_M00121   Heme biosynthesis, plants and bacteria, glutamate => heme amd_M00846   Siroheme biosynthesis, glutamyl-tRNA => siroheme amd_M00926   Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme Brite KEGG Orthology (KO) [BR:amd00001]  09100 Metabolism   09108 Metabolism of cofactors and vitamins    00860 Porphyrin metabolism     AMED_0482 (hemD) Enzymes [BR:amd01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.107  uroporphyrinogen-III C-methyltransferase      AMED_0482 (hemD)  4. Lyases   4.2  Carbon-oxygen lyases    4.2.1  Hydro-lyases     4.2.1.75  uroporphyrinogen-III synthase      AMED_0482 (hemD) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HEM4 TP_methylase Motif Other DBs NCBI-ProteinID:  ADJ42303 UniProt:  A0A0H3CVJ9 LinkDB All DBs Position 486415..487947 Genome browser AA seq 510 aa AA seqDB search MTPARKTTGRVAFVGSGPGDAGLLTVRAQELLTKAEVVVTDPDVPQSVLAMAAEGAEVRP AVGEATEVAKDLTTEAKAGRLVLRLVAGDPLTTPAVVAEVQAVARTSAVFDVIPGVSPAA AVPAYAGVALGGTHTEVDVRGDVDWAALAAAPGPLVLHATSAHLAEAASALTGNGVPAST PVAVTANGTINTQRTLDTTLEKVANDAGELVGPLIVTIGQAAGQRSKLSWWESRSLYGWK VLVPRTKEQAGEMAERLRGHGATSHEVPTISVEPPRSPAQMERSVKGLVDGRYQWIVFTS TNAVRAVWEKFEEFGLDARAFSGVKIACVGESTAAKVRSFGIIPELIPSGEQSSEGLLAE FPPYDDVLDPVDRVLLPRADIATETLSAGLRERGWEIDDVTAYRTVRAAPPPAETREMIK TGGFDAVCFTSSSTVRNLVGIAGKPHTRTLVACIGPKTAETAVEFGLRVDVQPEKADVPH LVDALAEHAARLRAEGALPPPRKAKRARRS NT seq 1533 nt NT seq  +upstreamnt  +downstreamnt atgacccccgcgcgaaagaccaccgggcgcgtagcgttcgtgggctccggccccggcgac gccggcctgctcacggtccgtgcccaggagctgctgaccaaggccgaagtggtggtgacc gatcccgacgtgccgcagtccgtgctggccatggccgccgaaggcgccgaggtccggccc gccgtcggcgaggccaccgaggtcgccaaggacctgaccaccgaggccaaggccggccgg ctggtgctgcggctggtcgcgggcgacccgctgaccaccccggccgtggtggccgaggtc caggcggtcgcgcgcacgagtgccgtgttcgacgtcatcccgggtgtctccccggccgcg gccgtcccggcgtacgcgggcgtcgcgctgggcggcacgcacaccgaggtcgacgtccgc ggtgacgtcgactgggcggccctggccgccgcgcccggcccgctggtgctgcacgcgacg tcggcgcacctggccgaggccgcgtcggcgctgaccggcaacggcgtcccggcgtcgacc ccggtcgcggtcaccgcgaacggcaccatcaacacccagcgcaccctcgacaccacgctc gagaaggtcgccaacgacgccggcgagctcgtcgggccgctgatcgtcacgatcggccag gccgccgggcagcgctcgaagctgtcgtggtgggagtcgcggtcgctctacggctggaag gtcctggtgccgcgcaccaaggagcaggccggcgagatggccgagcgcctgcgcggccac ggcgcgacgtcgcacgaggtgccgaccatctcggtcgagccgccccgcagcccggcgcag atggagcggtcggtcaagggcctggtcgacggccgctaccagtggatcgtcttcacctcc accaacgcggtccgcgcggtgtgggagaagttcgaggagttcggcctggacgcccgcgcg ttctccggcgtgaagatcgcctgtgtgggtgagtcgaccgcggcgaaggtgcgctcgttc ggcatcatcccggagctgatcccctcgggcgagcagtcgtccgaaggcctgctggccgag ttcccgccgtacgacgacgtgctggacccggtcgaccgcgtgctgctgccgcgggccgac atcgccaccgagacgctgtcggccggcctgcgcgaacgcggctgggagatcgacgacgtg acggcctaccggaccgtccgggcggcgccgccgcccgccgagacccgcgagatgatcaag accggcggcttcgacgcggtctgcttcacctcgtcctcgaccgtgcggaacctggtcggc atcgccggcaagccgcacacccgcacgctggtcgcgtgcatcggcccgaagaccgccgag accgcggtggagttcgggctccgggtcgacgtccagccggagaaggcggacgtcccgcac ctggtggacgcgctggccgagcacgccgcgcggcttcgcgcggaaggtgcactgccgccg ccgcggaaggcgaagcgggcccgccgctcctga

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