Actinosynnema mirum: Amir_6728
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Entry
Amir_6728 CDS
T00957
Name
(GenBank) Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
ami
Actinosynnema mirum
Pathway
ami00860
Porphyrin metabolism
ami01100
Metabolic pathways
ami01110
Biosynthesis of secondary metabolites
ami01120
Microbial metabolism in diverse environments
ami01240
Biosynthesis of cofactors
Module
ami_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
ami_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
ami_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Amir_6728
Enzymes [BR:
ami01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Amir_6728
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Amir_6728
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ACU40525
UniProt:
C6WNG1
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Position
complement(7860477..7862009)
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AA seq
510 aa
AA seq
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MTRARKTPGRVAFVGSGPGDTGLLTVRARDLLGKAELVVTDPDVPAEVVALVPDGVEVRP
AVGEPADVAKDLVAEAKNGAAVVRLVAGDPLTLDSVVKEAHAVSKTTIAFDVVPGVPAGT
AVPAYAGVALGAVHTEADVRGAVDWAGLASATGTLVLHATGGHLAEAASSLVEHGLAPQT
PVAVTADGTGFSQRTVDTTLASLAADAGELSGPLVVTVGSAVANRPKLSWWESRALYGWR
VLVPRTKEQAGAMSDRLHSHGAIPVEVPTISVEPPRSPAQMERSVKGLVDGRYQWVVFTS
TNAVRAVWEKFREFGLDARAFSGVKIACVGEATAAKVRGFGIIPELVPSGEQSSEGLLAD
FPPYDDILDPVDRVLLPRADIATETLAAGLRDRGWEIDDVTAYRTVRAAPPPADTREMIK
SGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPQTAETAREFGLRVDVQPEDANVPA
LVDALAQHAARLRAEGALPPPRKTKRLRRS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcgcgcgcaagacccccggccgagtcgccttcgtgggctccggcccaggtgac
accgggctcctcacggtccgggcccgcgacctgctcggcaaggccgagctggtcgtgacg
gacccggacgtgcccgccgaggtggtcgccttggtccccgacggcgtcgaggtccggccc
gcggtcggcgagcccgccgacgtggcgaaggacctggtggccgaggccaagaacggcgcg
gcggtggtccggctggtcgcgggcgacccgctgaccctggactccgtggtgaaggaggcg
cacgccgtctccaagaccacgatcgccttcgacgtggtccccggcgtgcccgcgggcacg
gccgtccccgcgtacgcgggggtcgcgctgggcgcggtgcacaccgaggccgacgtgcgc
ggcgccgtggactgggccgggctcgcctcggcgacgggcacgctcgtgctgcacgcgacc
ggcggccacctggccgaggcggcgtcctcgctggtggagcacggcttggccccgcagacc
ccggtcgcggtgaccgccgacggcaccggcttcagccagcgcaccgtcgacaccacgctg
gcctcgctggccgcagacgcgggcgagctgtccggcccgctggtggtcacggtcggcagc
gcggtcgcgaaccggcccaagctgtcctggtgggagtcgcgggcgctgtacggctggcgc
gtgctggtgcccaggaccaaggagcaggcgggcgcgatgagcgaccggctgcactcgcac
ggcgccatcccggtggaggtgccgacgatctccgtcgagccgccgcgcagcccggcgcag
atggagcgctcggtcaagggcctggtcgacggccgctaccagtgggtcgtgttcacctcg
accaacgcggtgcgcgcggtgtgggagaagttccgcgagttcggcctggacgcccgcgcg
ttctccggcgtgaagatcgcctgcgtcggcgaggccacggcggcgaaggtgcgcggcttc
gggatcatcccggagctggtgccgtccggcgagcagtcctccgagggcctgctggccgac
ttcccaccgtacgacgacatcctggacccggtcgaccgggtgctgctgccgcgcgccgac
atcgccaccgagaccctcgcggccgggctgcgcgaccggggctgggagatcgacgacgtg
acggcctaccgcaccgtgcgggccgccccgccgcccgccgacacccgcgagatgatcaag
tccggcgggttcgacgcggtgtgcttcacctcgtcgtccacggtccggaacctggtcggc
atcgcgggcaagccgcacgcccgcacgctggtggcctgcatcggcccgcagacggcggag
acggcgcgcgagttcggcctgcgcgtggacgtgcagcccgaggacgcgaacgtcccggcg
ctggtggacgcgctggcgcagcacgcggcgaggctgcgcgccgagggcgccctgcccccg
ccgcgcaagaccaagcgcctgcgcaggtcctga
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