Ailuropoda melanoleuca (giant panda): 100468338
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Entry
100468338 CDS
T01329
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00230
Purine metabolism
aml01100
Metabolic pathways
aml04927
Cortisol synthesis and secretion
aml04934
Cushing syndrome
aml05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100468338 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
100468338 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100468338 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100468338 (PDE8B)
Enzymes [BR:
aml01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
100468338 (PDE8B)
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Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_3
PAS_4
PAS_8
Motif
Other DBs
NCBI-GeneID:
100468338
NCBI-ProteinID:
XP_034512292
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Position
3:52342286..52594896
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AA seq
783 aa
AA seq
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MEQTRCRPSARQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIA
RTPESALECFLDKHHEIIVIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDRE
EASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAI
EITSDDHVIQYVNPAFERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQ
GVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQLHKLHRDSGDNSQ
TESHSLRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINA
AQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYV
FTKNVHQSHSHLAMPITINDVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFS
RFGVCEFLHCSETTLRAWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQ
LDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKC
NIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAESEGSDCECNPTG
KNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVF
DRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLP
SDS
NT seq
2352 nt
NT seq
+upstream
nt +downstream
nt
atggagcagacgcgctgccggccgagcgcccgccaggtctcgtctgcggaggtgcgcatt
gggcccatgagactgacgcaggatcctattcaggttttgctgatctttgcaaaggaagat
agtcagagtgatggattctggtgggcctgtgacagagctggttatagatgcaatattgct
cggactccagagtcagcccttgaatgctttctagataaacatcatgaaattatcgtaata
gatcacagacagactcgaaactttgatgcagaggcggtgtgcaggtcgatccgggccaca
aatccttccgagcacacggtgatccttgcggtggtttcacaagcatcgggtgaccgtgaa
gaggcctcagtcctccctctcctgcatgcaggcttcaacaggagatttatggagaatagc
agcataattgcttgctataatgaactgattcaaatagaacacggggaagttcgctcacag
ttcaaactacgggcctgtaattcagtgtttacggcattagaccactgtcatgaagccata
gaaattacaagcgatgaccatgtgattcagtacgtcaacccagcctttgaaaggatgatg
ggctaccacaaaggcgagctgctggggaaagagctcgccgagctgcccaaaagtgataag
aaccgggccgaccttctcgacaccatcaacacatgcatcaagaagggcaaggagtggcag
ggggtttactatgccagacggaaatccggggacagcatccaacagcacgtgaagatcacc
ccggtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactgtgttgt
accactgacaataataagcagcttcacaagcttcatcgtgattcaggagacaattctcag
acagagtctcattcactcagatacaagaacagaaggaaagagtccattgatgtgaaatcg
atatcctctcgaggcagtgatgcaccaagcctacagaaccgtcgctatccatccatggca
aggatccattccatgaccattgaggctcccatcacaaaggttataaatataatcaatgcg
gcccaagagaacagccccgtcacagtagcagaagccttggacagagttttagaaatttta
cggaccacagaactgtattccccccagctgggtaccaaagatgaagatccccacaccagc
gatcttgttggaggcctgatgactgatggcttgagaaggttgtcaggaaacgagtatgtg
ttcactaagaatgtgcaccagagtcacagtcaccttgcgatgccaataaccatcaacgat
gtccccccttgtatcgctcaattacttgataatgaggaaagttgggagttcaacatcttt
gaattggaagctgttacacataaaaggccattggtttacctgggcttaaaggtattttct
cggtttggagtatgtgaatttttacactgctctgaaactactcttcgggcctggctccaa
gtgattgaagccaactaccactcctccaatgcctaccataactccacccatgccgctgat
gtcctgcatgccactgctttcttcctcggaaaggaacgagtgaagggaagcctcgatcag
ctggatgaggtggcagcgctgattgctgccacagtccacgatgtggatcacccggggagg
accaactcgttcctgtgcaatgcaggcagtgaactggctgtgctctataacgacactgct
gtcttggagagtcaccataccgccctggctttccagctcacagtcaaggacagcaaatgc
aacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctattattgac
atggtgttagcaacagagatgaccaaacacttcgaacacgtgaacaaatttgtgaacagc
atcaacaagccaatggcagctgagagtgagggcagcgactgtgaatgcaaccctactggg
aagaactttcctgaaaaccaaatcctgatcaaacgtatgatgataaagtgtgctgatgta
gccaacccatgtcgccccctggacctgtgcatcgaatgggctgggaggatctcggaggag
tatttcgcacagactgatgaagagaagagacaggggctccctgtggtgatgccagtgttt
gaccggaatacctgcagcatccccaaatcccaaatctccttcattgactacttcataaca
gacatgtttgatgcttgggatgcctttgcccatctgccagccctgatgcaacatttggct
gataactacaaacactggaagacattagatgacctcaagtgcaaaagtctgaggcttcca
tctgacagctaa
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