Ailuropoda melanoleuca (giant panda): 100472842 Help Entry 100472842         CDS       T01329                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml01524   Platinum drug resistance aml04115   p53 signaling pathway aml04210   Apoptosis aml04215   Apoptosis - multiple species aml04217   Necroptosis aml04620   Toll-like receptor signaling pathway aml04621   NOD-like receptor signaling pathway aml04622   RIG-I-like receptor signaling pathway aml04623   Cytosolic DNA-sensing pathway aml04625   C-type lectin receptor signaling pathway aml04657   IL-17 signaling pathway aml04668   TNF signaling pathway aml04932   Non-alcoholic fatty liver disease aml04936   Alcoholic liver disease aml05010   Alzheimer disease aml05016   Huntington disease aml05022   Pathways of neurodegeneration - multiple diseases aml05132   Salmonella infection aml05134   Legionellosis aml05142   Chagas disease aml05145   Toxoplasmosis aml05152   Tuberculosis aml05160   Hepatitis C aml05161   Hepatitis B aml05162   Measles aml05163   Human cytomegalovirus infection aml05164   Influenza A aml05165   Human papillomavirus infection aml05167   Kaposi sarcoma-associated herpesvirus infection aml05168   Herpes simplex virus 1 infection aml05169   Epstein-Barr virus infection aml05170   Human immunodeficiency virus 1 infection aml05200   Pathways in cancer aml05203   Viral carcinogenesis aml05416   Viral myocarditis aml05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     100472842 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100472842 (CASP8)    04215 Apoptosis - multiple species     100472842 (CASP8)    04217 Necroptosis     100472842 (CASP8)    04115 p53 signaling pathway     100472842 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100472842 (CASP8)    04621 NOD-like receptor signaling pathway     100472842 (CASP8)    04622 RIG-I-like receptor signaling pathway     100472842 (CASP8)    04623 Cytosolic DNA-sensing pathway     100472842 (CASP8)    04625 C-type lectin receptor signaling pathway     100472842 (CASP8)    04657 IL-17 signaling pathway     100472842 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100472842 (CASP8)    05203 Viral carcinogenesis     100472842 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100472842 (CASP8)    05161 Hepatitis B     100472842 (CASP8)    05160 Hepatitis C     100472842 (CASP8)    05164 Influenza A     100472842 (CASP8)    05162 Measles     100472842 (CASP8)    05168 Herpes simplex virus 1 infection     100472842 (CASP8)    05163 Human cytomegalovirus infection     100472842 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     100472842 (CASP8)    05169 Epstein-Barr virus infection     100472842 (CASP8)    05165 Human papillomavirus infection     100472842 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     100472842 (CASP8)    05134 Legionellosis     100472842 (CASP8)    05152 Tuberculosis     100472842 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100472842 (CASP8)    05142 Chagas disease     100472842 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     100472842 (CASP8)    05016 Huntington disease     100472842 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     100472842 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100472842 (CASP8)    05416 Viral myocarditis     100472842 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100472842 (CASP8)    04932 Non-alcoholic fatty liver disease     100472842 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100472842 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:aml01002]     100472842 (CASP8) Enzymes [BR:aml01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      100472842 (CASP8) Peptidases and inhibitors [BR:aml01002]  Cysteine peptidases   Family C14: caspase family    100472842 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  100472842 NCBI-ProteinID:  XP_002915893 Ensembl:  ENSAMEG00000006066 LinkDB All DBs Position Unknown AA seq 486 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLVTYLDTSKEEMEQELQIPGRAQISAYRVMLFQISEDVSKLELRSF KFFLSQEISRCKLHDDLNLFDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREQTLSPQRSLDEISNDMSQLLVGEESLRVLPMSDSPGEQDCEPETSDKVYRMESKPR GYCLIFNNYDFSIARKEVPKLQSIKDRNGTDLDADALCQTFSELHFEIVPFKDCTAKKIC EVLKSYQCMDHSSRDCFICCILSHGDKGIIYGSDGQEVPIYELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQKEAYLEMDSSYQKRYIPEDADFLLGMATVNNCVSYR NPMEGTWYIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDRKNMGKQMPQPTFTLRKK LFFPLN NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt atgaatttcagcaaatgcctctataatattggagaacagctggacagtgatgagctggcc tccctcaagttcctgagcatggactacatcccacagaagaagcaggaacccatcaaggat cccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctggttacctacctggac accagcaaggaggagatggagcaggagcttcaaataccaggcagagcccagatctctgcc tacagggtcatgctttttcagatttcagaagatgtaagcaaattggaattgaggtccttt aagttttttttgagccaggagatctccagatgtaaactgcatgatgacttgaacttgttt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggataccctg aaaagaatctgtgaccaaattaacaagagcctgctgaagaaaatcacggattatgaagaa ttaagcagagagcaaacactgagccctcaaagaagtctagatgaaatttcaaatgatatg tctcagttgcttgtaggggaggaatccctgagggtactgccaatgtcggactctccagga gaacaggactgtgaaccagagacatcggacaaagtttaccgaatggaaagcaaacctcga ggatattgtttgatctttaacaattacgactttagcatagcacggaaggaagtgcccaaa cttcagagcattaaggataggaatgggacagacttggatgcagatgctttgtgtcagacc tttagtgagcttcattttgagatcgtgcctttcaaagactgtacagccaagaaaatctgt gaggttctgaaatcctaccaatgcatggaccactctagcagggattgctttatctgctgc atcctctcccatggagacaagggcatcatctatggctctgatgggcaagaagtccccatc tatgagctgacttcttacttcactggttcaaagtgcccttcccttgcaggcaagcccaaa atcttttttattcaggcttgtcaaggggataactaccagaaaggtatagctgttgagact gactctgaacagaaggaagcctatttagaaatggactcatcctatcagaagagatatatc ccagaagacgctgactttctgctggggatggccactgtgaataattgtgtttcctaccga aaccccatggaaggaacctggtatatccagtcactttgccagagcctgagagaaagatgt cctaggggcgaagatattctcaccatccttaccgaggtgaactttgaagtgagcaataag gatgacaggaaaaacatggggaaacaaatgccacaacctactttcacactgaggaaaaaa ctctttttccctcttaattga

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