Ailuropoda melanoleuca (giant panda): 100473956 Help Entry 100473956         CDS       T01329                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml04010   MAPK signaling pathway aml04014   Ras signaling pathway aml04015   Rap1 signaling pathway aml04022   cGMP-PKG signaling pathway aml04066   HIF-1 signaling pathway aml04068   FoxO signaling pathway aml04072   Phospholipase D signaling pathway aml04150   mTOR signaling pathway aml04151   PI3K-Akt signaling pathway aml04152   AMPK signaling pathway aml04211   Longevity regulating pathway aml04213   Longevity regulating pathway - multiple species aml04520   Adherens junction aml04910   Insulin signaling pathway aml04913   Ovarian steroidogenesis aml04923   Regulation of lipolysis in adipocytes aml04930   Type II diabetes mellitus aml04931   Insulin resistance aml04932   Non-alcoholic fatty liver disease aml04960   Aldosterone-regulated sodium reabsorption aml05010   Alzheimer disease aml05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:aml00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100473956 (INSR)    04014 Ras signaling pathway     100473956 (INSR)    04015 Rap1 signaling pathway     100473956 (INSR)    04066 HIF-1 signaling pathway     100473956 (INSR)    04068 FoxO signaling pathway     100473956 (INSR)    04072 Phospholipase D signaling pathway     100473956 (INSR)    04022 cGMP-PKG signaling pathway     100473956 (INSR)    04151 PI3K-Akt signaling pathway     100473956 (INSR)    04152 AMPK signaling pathway     100473956 (INSR)    04150 mTOR signaling pathway     100473956 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     100473956 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100473956 (INSR)    04923 Regulation of lipolysis in adipocytes     100473956 (INSR)    04913 Ovarian steroidogenesis     100473956 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100473956 (INSR)   09149 Aging    04211 Longevity regulating pathway     100473956 (INSR)    04213 Longevity regulating pathway - multiple species     100473956 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     100473956 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     100473956 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100473956 (INSR)    04932 Non-alcoholic fatty liver disease     100473956 (INSR)    04931 Insulin resistance     100473956 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:aml01001]     100473956 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:aml04090]     100473956 (INSR) Enzymes [BR:aml01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      100473956 (INSR) Protein kinases [BR:aml01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    100473956 (INSR) CD molecules [BR:aml04090]  Proteins   100473956 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  100473956 NCBI-ProteinID:  XP_034513605 Ensembl:  ENSAMEG00000008175 LinkDB All DBs Position 4:6113842..6239484 Genome browser AA seq 1369 aa AA seqDB search MGAGAGRGAATAPLLLAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VVFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFEAEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRPSRKRRALGDGANVTAAAPTVPGFPNSSTSAPTSPE EHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYVSARTMPEAKADDI VGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRL RGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIG SIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKISLLRELGQGS FGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVV SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAK KFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVF TTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCW QFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRAS HSQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNPS NT seq 4110 nt NT seq  +upstreamnt  +downstreamnt atgggcgccggggctgggcggggggcggcgaccgcgccgctgctgctggcggtggccgcg ctgctgctgggtgccgcgggccacctgtaccccggagaggtgtgccctggcatggatatc cggaacaacctcacgaggttgcatgagctggccaactgctcagtcatcgaaggacatttg cagatactgttgatgttcaaaacgaggcccgaggatttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctcgcgtctcttcttcaactacgcgctg gtcgtcttcgagatggttcacctgaaggagcttggcctttatagcttgatgaacattacc aggggctccgtccgcattgagaagaataatgagctctgctacctggccaccatcgactgg tcgcgcatcctggattccgtggaggataattacattgtgctgaacaaagacgacaatgag gagtgtggggacatctgtccaggcactgcaaagggcaagaccaactgccccgccactgtc atcaatgggcagtttgtcgagaggtgttggacacacagccactgccagaaagtttgtccc accatctgcaagtcgcacggctgcaccgccgagggcctctgctgccacagcgagtgttta ggcaattgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gatggcaggtgcgtggagacctgcccgcccccgtactatcacttccaagactggcgctgc gtgaacttcagcttctgccaggatttgcacaacaaatgcaagaactcccggagacagggc tgccaccagtacgtcattcataacaacaagtgcatccccgagtgcccctctggctacacg atgaattccagcaacctgatgtgcaccccatgcctgggcccctgtcccaaggtctgccac attctggagggcgagaagaccatcgactcggtgacctctgcccaggagcttcgaggctgc actgttgtcaacggaagcctcatcatcaacattcgagggggcaacaacctggcagctgag ctggaggccaaccttggactcattgaagaaatttccgggtatctgaaaatccggagatcc tatgctcttgtgtccctttcctttttccggaagttacggctgattcgaggagagaccttg gaaatcgggaactactctttctacgccttggacaaccagaacctaaggcagctatgggac tggagcaaacacaacctcactatcactcaggggaagctcttcttccactataatcccaaa ctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag aggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaacgaactcctt aagttttcttacatccggacatcatatgacaagatcttgctgaaatgggagccgtactgg ccccctgacttccgagacctcctgggtttcatgcttttctacaaagaggccccttatcag aatgtgaccgagttcgatgggcaggatgcgtgtggctccaacagctggacggtggtggac attgacccgcctctgcggtccaatgaccccaagtcgcagaaccacccagggtggctgatg cggggtctcaagccctggacccagtatgccatctttgtcaagactttggtcaccttttct gatgaacgccgcacgtacggggccaagagtgacatcatctatgtgcagacagatgccact aacccttctgtccccctggatccaatctccgtctcaaattcctcgtcccagattattctg aagtggaagcctccctctgaccccaacggcaacatcacacactacctggttttctgggag aggcaggcagaagacagtgagctgtatgaattggattattgcctcaaagggttgaagctg ccctcccggacctggtctccgccgttcgaggccgagggctcgcagaagcacaaccagagc gagtacgaggagtctgccggcgagtgctgttcctgccccaagacggactctcagatcctc aaggagctggaggagtcctcgttcaggaagaccttcgaggattacctgcacaatgtggtg ttcgtccccaggccatcgcggaaacgcagggccctcggtgacggtgccaatgtgacggcg gccgcgcccacggttccgggtttccccaacagctccaccagcgcacccacgagcccggag gagcacaagcccttcgagaaagtggtgaacaaggaatccctggtcatctctgggctgcgt cacttcactggctaccgcatcgagctgcaggcttgcaaccaagactccccggaggagagg tgcagcgtggcggcttatgtcagcgccaggaccatgcccgaagctaaggcagacgacatc gttggccccgtgacccacgaaatcttcgagaacaacgttgttcacttgatgtggcaggag ccaaaggaacccaacggtctgatcgtgttgtatgaagtgagttaccgacgttacggtgat gaggagctgcacctctgtgtctcccgcagacactttgctctggagcggggctgcaggctg cgcgggctgccgccggggaattatagcgtgcgagtccgggccacctccctggccggcaac ggctcctggacagaagccacctacttctacgtgacagactatttagatgtcccatcgaat attgcaaaaatcatcatcggccccctcatctttgtctttctcttcagtgttgtgattgga agtatttacctgttcctgagaaagaggcagccggatgggccactgggaccgctgtatgct tcttcaaaccccgagtacctcagtgccagtgatgtatttccatgttctgtgtatgtgccg gacgagtgggaggtcccccgggagaagatcagtctgctgcgtgagctggggcagggctcc ttcggcatggtgtacgaaggcaacgccagagacatcgtcaagggcgaggcggagacccgc gtggcagtgaagacggtcaatgagtcggccagtctgcgggagaggattgagtttctcaac gaggcctccgtcatgaagggcttcacctgtcatcacgtggtccgcctcctgggggtggtg tccaagggccagccgacgctggtggtgatggagctgatggcccacggagacctgaagagc tacctccgctccctgcggccggaggctgagaataaccccggccgccctccccctaccctg caagagatgattcagatggcggcggagatcgccgacgggatggcctacctgaacgccaag aagttcgtgcaccgggatctcgcggcccgaaactgcatggtcgcccacgacttcaccgtc aaaattggagactttgggatgaccagagacatctatgaaacggattactaccggaaagga ggcaagggtctgctccctgtgcggtggatggccccggaatccctgaaggacggggtcttt accacttcttctgacatgtggtcctttggcgtggtcctttgggaaatcaccagcttggca gaacagccgtaccagggtctgtctaatgaacaggtgttgaaattcgtcatggatggaggg tatctggatcaacctgacaattgtccagagagagtcaccgacctgatgcgcatgtgctgg cagttcaatcccaagatgcggcccaccttcctggagatcgtcgacctgctcaaggacgac ctgcatcctagctttccggaagtttccttcttccacagcgaggagaacaaggcgcctgag agcgaggagctggagatggagttcgaggacatggagagtgtccccctggatcgggcctca cactctcagagggaggaggctgggggccgggatggagggtcctccctgggcctcaagcga aactacgaggagcacatcccctacacccacatgaacgggggcaagaaaaacggacggatt ctgacgctgccgaggtcgaatccttcctaa

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