Ailuropoda melanoleuca (giant panda): 100474476
Help
Entry
100474476 CDS
T01329
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml04140
Autophagy - animal
aml04141
Protein processing in endoplasmic reticulum
aml04210
Apoptosis
aml04932
Non-alcoholic fatty liver disease
aml05010
Alzheimer disease
aml05012
Parkinson disease
aml05014
Amyotrophic lateral sclerosis
aml05016
Huntington disease
aml05017
Spinocerebellar ataxia
aml05022
Pathways of neurodegeneration - multiple diseases
aml05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100474476 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100474476 (ERN1)
09143 Cell growth and death
04210 Apoptosis
100474476 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100474476 (ERN1)
05012 Parkinson disease
100474476 (ERN1)
05014 Amyotrophic lateral sclerosis
100474476 (ERN1)
05016 Huntington disease
100474476 (ERN1)
05017 Spinocerebellar ataxia
100474476 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
100474476 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100474476 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100474476 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aml01001
]
100474476 (ERN1)
Enzymes [BR:
aml01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100474476 (ERN1)
Protein kinases [BR:
aml01001
]
Serine/threonine kinases: Other
IRE family
100474476 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
100474476
NCBI-ProteinID:
XP_019660727
Ensembl:
ENSAMEG00000002855
LinkDB
All DBs
Position
13:complement(31031566..31125529)
Genome browser
AA seq
1168 aa
AA seq
DB search
MGEDLTFPVLGDLAQGVGFSAAIRAGALAFPRATASALCLLVPIPLALQLLQAKAVSTLP
SCQSLPFSSAALSSELMHISPKPGPPAGEPGGPSYAQARTLALQPDPLRHAQAQRGLKGS
ASEEHPTPRVCARKPVPCSPQPRRPGSDYSSHHPRQQSNTCFFLECHHCRPPATHPAPGP
THQGPAQTTLTQPASQLRKDRVRASGFYLKEIFGSPSTVTLPETLLFVSTLDGSLHAVSK
RTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQAS
PCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYD
TKTRELRWNATYFDYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVV
AFYVWQREGLKKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVG
KYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLK
GKNKLNYLRNSWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLV
DQTSENAPTTISQDVEEKYEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLS
MHQQQQLQHQQFQKELEKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTS
PRASNHSLHSSGSASKAGASPFLEQDDVDEETSMVIVGKISFCPKDVLGHGAEGTIVYRG
MFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATL
QEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMI
SDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVIS
EGSHPFGKSLQRQANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKH
PFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKF
RTYKGGSVRDLLRAMRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAME
PCSHERLFQPYYFHEPPEPRPPVTPDTL
NT seq
3507 nt
NT seq
+upstream
nt +downstream
nt
atgggtgaagatctgaccttcccagtattaggagacttagctcaaggtgtggggttctcg
gctgccatccgtgctggagcactggcctttcctcgtgccacagcttctgccctctgcctg
ctggtgcccattccactcgccctgcagttattacaggccaaagcagtttcaacactgccc
tcatgccagtctttgcccttcagcagcgctgccttgtcctcagaactgatgcacatctca
cctaaaccagggccgccggcgggggaaccaggcggccccagttatgcgcaagcgcgtact
ctggcgctgcagcctgaccccctgcgccacgcgcaggcgcaacgggggctcaaaggcagc
gcgtcggaagaacacccaacaccgcgggtgtgcgcccgcaagcctgttccctgctcgccg
caaccccggaggcctggctcagattatagttcgcatcacccacgtcagcagtctaacacg
tgcttttttttggaatgtcatcactgcaggccccccgcgacccacccggctccagggccg
acccaccagggccccgcacagacaacactcacccagccagcctcacagctccggaaagac
cgagtcagggcctccggcttctacttaaaggagatttttggaagtcccagcacagtgaca
cttcctgaaaccttgttgtttgtgtcaactctggatggaagtttgcatgctgtcagcaag
aggacaggctcaatcaaatggactttaaaagaagatcctgttctgcaggttccaacacat
gtggaagagcctgctttcctcccagatcccaatgatggcagcctgtatacgcttgggggc
aagaataatgaaggcctgacgaaacttccttttaccatcccggagttggtacaggcatcc
ccatgccgaagttcagatggaattctctacatgggtaaaaagcaggacatttggtacgtt
atcgatcttctgactggggagaagcagcagactttgtcatcggcctttgcagacagtctc
tgcccatcaacctctttgctgtatcttgggcgaacagagtacaccatcaccatgtatgac
accaaaacccgagagctccggtggaacgccacctactttgactacgcagcctcgctgcct
gaggacgacggggactacaagatgtctcactttgtgtccaacggcgatgggctggtggtg
accgtggacagtgaatctggcgacgtcctgtggatccaaaactacgcttcccccgtggtg
gccttttacgtctggcagcgggagggtctgaagaaggtgatgcacatcaacgtcgccgtg
gagaccctgcgctacctgaccttcatgtctggggaggtgggccgcatcaccaagtggaag
tacccgttccccaaggagacggaggccaagagcaagctgacgcccaccctgtatgttggg
aaatactctaccagcctgtatgcctccccctccatggttcacgagggggttgccgttgtg
ccccgaggcagtactcttcctttgctggaaggcccccagaccgatggggtcaccattggg
gacaaaggggaatgtgtgatcacacccagcacagacctcaagtttgaccctgggctcaaa
ggcaagaacaagctcaactacctgaggaactcctggcttctgataggacaccatgaaacc
cccttgtctgcgtctaccaaaatgctggagagattccccaacaatctgcccaaacatcgg
gaaaacgtgattcctgccgattcagagaagaagagctttgaggaagttatcaacctggtt
gaccagacttcagaaaacgcgcctaccaccatctcacaggatgtggaagagaaatacgag
catgcccctgccaagcccgaggcccccgtggactccgtgctcaaggacattgccaccatc
atcctgagcaccttcctgctcatcggctgggtggccttcatcatcacctaccccttgagc
atgcatcagcagcagcagctccagcaccagcagttccagaaggaactagagaaaatccag
ctcctgcagcagcagcagctgcccttccatccacctggagacgtggctcaagatgctgag
ctcttggactcgtctggcctgtactctgagagctcaggcaccagcagccccagcacgtcc
cccagagcctccaaccactcgctccactccagtggctcagcctccaaggctggtgccagc
cccttcctggagcaggatgatgtggatgaggaaaccagcatggtgatagttgggaaaatt
tcattctgtcccaaggacgtgctgggtcatggagctgagggcacgattgtgtaccggggc
atgtttgacaaccgcgacgtggccgtcaagaggatcctccccgagtgtttcagtttcgcg
gaccgggaagtccagctgcttcgagaatcggatgagcaccccaacgtgatccgttacttc
tgcacggagagggaccggcagttccagtacattgccatcgagctgtgtgcggccaccctg
caggagtacgtggagcagaaggactttgcccacctcggcctggagcccatcaccttgttg
caacagaccacctcaggcctagcccatctgcactccctcaacattgttcacagagacctg
aagccccacaacattctcctctccatgcccaatgcacatggcaggatcaaggccatgatc
tcggacttcggcctctgcaagaagctggcggtcggcaggcacagtttcagccgccgctca
ggagtgccgggcacagaaggctggattgctccagagatgctgagcgaagactgcaaggac
aacccgacctacacggtggacatcttctctgcgggctgtgtcttttactacgtgatatca
gagggcagccacccttttggcaagtccctgcagcggcaggccaacatcctcctgggtgcc
tacagcctcgactgcttgcaccccgagaagcacgaggatgtcattgcccgggaattaata
gagaagatgatcgcaatggatcctcagaaacgcccttcggcgaagcacgtgctgaaacac
ccattcttctggagcctggaaaagcagctccagttctttcaggatgtgagtgaccgaata
gagaaggagtccctggacggcccgatagtgaagcagctggagcgaggcgggagagctgtg
gtgaagatggactggagggagaacatcactgtccccctgcagacagatttgcggaaattc
agaacctataaaggtggctccgtccgagacctcctccgagccatgagaaacaagaagcat
cactaccgggagctgcccgtggaggtgcgggagacgctgggctccctccccgacgacttc
gtgcgttacttcacgtcccgcttcccccacctcctgtcccacacctaccgggccatggag
ccgtgcagccacgagcggctcttccagccctactacttccacgagcccccagagccccgg
cctccagtgactccagacaccctttga
DBGET
integrated database retrieval system
