KEGG   Ailuropoda melanoleuca (giant panda): 100480483
Entry
100480483         CDS       T01329                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml01522  Endocrine resistance
aml04010  MAPK signaling pathway
aml04015  Rap1 signaling pathway
aml04068  FoxO signaling pathway
aml04071  Sphingolipid signaling pathway
aml04114  Oocyte meiosis
aml04148  Efferocytosis
aml04218  Cellular senescence
aml04261  Adrenergic signaling in cardiomyocytes
aml04370  VEGF signaling pathway
aml04380  Osteoclast differentiation
aml04550  Signaling pathways regulating pluripotency of stem cells
aml04611  Platelet activation
aml04613  Neutrophil extracellular trap formation
aml04620  Toll-like receptor signaling pathway
aml04621  NOD-like receptor signaling pathway
aml04622  RIG-I-like receptor signaling pathway
aml04625  C-type lectin receptor signaling pathway
aml04657  IL-17 signaling pathway
aml04658  Th1 and Th2 cell differentiation
aml04659  Th17 cell differentiation
aml04660  T cell receptor signaling pathway
aml04664  Fc epsilon RI signaling pathway
aml04668  TNF signaling pathway
aml04670  Leukocyte transendothelial migration
aml04714  Thermogenesis
aml04722  Neurotrophin signaling pathway
aml04723  Retrograde endocannabinoid signaling
aml04728  Dopaminergic synapse
aml04750  Inflammatory mediator regulation of TRP channels
aml04912  GnRH signaling pathway
aml04914  Progesterone-mediated oocyte maturation
aml04917  Prolactin signaling pathway
aml04926  Relaxin signaling pathway
aml04932  Non-alcoholic fatty liver disease
aml04933  AGE-RAGE signaling pathway in diabetic complications
aml04935  Growth hormone synthesis, secretion and action
aml04936  Alcoholic liver disease
aml05014  Amyotrophic lateral sclerosis
aml05020  Prion disease
aml05022  Pathways of neurodegeneration - multiple diseases
aml05132  Salmonella infection
aml05133  Pertussis
aml05135  Yersinia infection
aml05140  Leishmaniasis
aml05142  Chagas disease
aml05145  Toxoplasmosis
aml05152  Tuberculosis
aml05161  Hepatitis B
aml05163  Human cytomegalovirus infection
aml05167  Kaposi sarcoma-associated herpesvirus infection
aml05169  Epstein-Barr virus infection
aml05170  Human immunodeficiency virus 1 infection
aml05171  Coronavirus disease - COVID-19
aml05205  Proteoglycans in cancer
aml05208  Chemical carcinogenesis - reactive oxygen species
aml05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
aml05415  Diabetic cardiomyopathy
aml05417  Lipid and atherosclerosis
aml05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100480483 (MAPK11)
   04015 Rap1 signaling pathway
    100480483 (MAPK11)
   04370 VEGF signaling pathway
    100480483 (MAPK11)
   04668 TNF signaling pathway
    100480483 (MAPK11)
   04068 FoxO signaling pathway
    100480483 (MAPK11)
   04071 Sphingolipid signaling pathway
    100480483 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100480483 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100480483 (MAPK11)
   04218 Cellular senescence
    100480483 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100480483 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100480483 (MAPK11)
   04613 Neutrophil extracellular trap formation
    100480483 (MAPK11)
   04620 Toll-like receptor signaling pathway
    100480483 (MAPK11)
   04621 NOD-like receptor signaling pathway
    100480483 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    100480483 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    100480483 (MAPK11)
   04660 T cell receptor signaling pathway
    100480483 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    100480483 (MAPK11)
   04659 Th17 cell differentiation
    100480483 (MAPK11)
   04657 IL-17 signaling pathway
    100480483 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    100480483 (MAPK11)
   04670 Leukocyte transendothelial migration
    100480483 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100480483 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    100480483 (MAPK11)
   04917 Prolactin signaling pathway
    100480483 (MAPK11)
   04926 Relaxin signaling pathway
    100480483 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    100480483 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100480483 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    100480483 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    100480483 (MAPK11)
   04722 Neurotrophin signaling pathway
    100480483 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100480483 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100480483 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    100480483 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100480483 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    100480483 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100480483 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100480483 (MAPK11)
   05161 Hepatitis B
    100480483 (MAPK11)
   05171 Coronavirus disease - COVID-19
    100480483 (MAPK11)
   05163 Human cytomegalovirus infection
    100480483 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100480483 (MAPK11)
   05169 Epstein-Barr virus infection
    100480483 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100480483 (MAPK11)
   05135 Yersinia infection
    100480483 (MAPK11)
   05133 Pertussis
    100480483 (MAPK11)
   05152 Tuberculosis
    100480483 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100480483 (MAPK11)
   05140 Leishmaniasis
    100480483 (MAPK11)
   05142 Chagas disease
    100480483 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100480483 (MAPK11)
   05020 Prion disease
    100480483 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    100480483 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100480483 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    100480483 (MAPK11)
   05415 Diabetic cardiomyopathy
    100480483 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100480483 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    100480483 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100480483 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100480483 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100480483 (MAPK11)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100480483 (MAPK11)
Protein kinases [BR:aml01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100480483 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975 FTA2 Kinase-like
Other DBs
NCBI-GeneID: 100480483
NCBI-ProteinID: XP_034499591
Ensembl: ENSAMEG00000002468
LinkDB
Position
15:complement(91144972..91151541)
AA seq 332 aa
GAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTP
ATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLK
PSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCI
MAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLRS
IFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKER
TVEEWKELTYQEVLSFKPAELPQSAGGLDIEQ
NT seq 999 nt   +upstreamnt  +downstreamnt
ggcgcctacggctcggtctgctcggcctatgacgcgcggctgcgccagaaggtggcggtg
aagaagctgtcgcgacccttccagtcgctgatccacgcgcggaggacttaccgcgagcta
cggctgctcaagcacctgaagcacgagaacgtcattgggctgctggacgtgttcacgccc
gccacctccatcgaggacttcagcgaagtgtacctggtgaccaccctgatgggcgccgac
ctgaacaacatcgtcaagtgccaggcgctgagcgacgagcacgtccagttcctggtttac
cagttgcttcgcgggctgaagtacatccactccgcggggatcatccaccgggacctgaag
cccagcaacgtggctgtgaacgaggactgcgagcttaggatcctggactttgggctagcc
cgccaggctgatgaggagatgaccggctatgtggccactcgctggtaccgggcccccgag
atcatgctgaattggatgcactacaaccagacagtggacatctggtctgtaggctgcatc
atggctgagctgctccaaggaaaggccctctttccaggaaatgactacatcgaccagctg
aagcgaatcatggaagttgtgggcacacccagccctgaggttctagcaaagatatcctca
gaacacgcccggacatacatccagtccctgccccctatgccccagaaggacctcaggagc
atcttccatggagccaaccccctggctgtggacctcctgggaaggatgctggtgcttgac
agtgaccagagggtcagtgcggccgaggccctggcccatgcctacttcagccagtaccac
gaccccgaagatgagcctgaggccgagccctacgatgagagcgttgaggccaaggagcgt
acagtggaggagtggaaggagctcacctaccaggaggtcctcagcttcaagcctgcagag
ctgccgcagtcagccggcggcctggacattgagcagtga

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