Ailuropoda melanoleuca (giant panda): 100483990
Help
Entry
100483990 CDS
T01329
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X2
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00220
Arginine biosynthesis
aml00330
Arginine and proline metabolism
aml01100
Metabolic pathways
aml04020
Calcium signaling pathway
aml04022
cGMP-PKG signaling pathway
aml04066
HIF-1 signaling pathway
aml04071
Sphingolipid signaling pathway
aml04151
PI3K-Akt signaling pathway
aml04370
VEGF signaling pathway
aml04371
Apelin signaling pathway
aml04611
Platelet activation
aml04915
Estrogen signaling pathway
aml04921
Oxytocin signaling pathway
aml04926
Relaxin signaling pathway
aml04931
Insulin resistance
aml04933
AGE-RAGE signaling pathway in diabetic complications
aml05415
Diabetic cardiomyopathy
aml05417
Lipid and atherosclerosis
aml05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100483990 (NOS3)
00330 Arginine and proline metabolism
100483990 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100483990 (NOS3)
04371 Apelin signaling pathway
100483990 (NOS3)
04066 HIF-1 signaling pathway
100483990 (NOS3)
04020 Calcium signaling pathway
100483990 (NOS3)
04071 Sphingolipid signaling pathway
100483990 (NOS3)
04022 cGMP-PKG signaling pathway
100483990 (NOS3)
04151 PI3K-Akt signaling pathway
100483990 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100483990 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100483990 (NOS3)
04921 Oxytocin signaling pathway
100483990 (NOS3)
04926 Relaxin signaling pathway
100483990 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100483990 (NOS3)
05418 Fluid shear stress and atherosclerosis
100483990 (NOS3)
05415 Diabetic cardiomyopathy
100483990 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100483990 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100483990 (NOS3)
Enzymes [BR:
aml01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100483990 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100483990
NCBI-ProteinID:
XP_011218395
Ensembl:
ENSAMEG00000013904
UniProt:
G1M5X2
LinkDB
All DBs
Position
1:206413647..206431142
Genome browser
AA seq
1201 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPNSSEPSRAPAPVPPPAPDHSPPLTRP
PDGPRFPRVKNWEVGSIAYDTLSAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQDPPPPEQ
LLSQARDFINQYYSSIKRSGSQAHEQRLQEMEAEIAAKGTYQLRESELVFGAKQAWRNAP
RCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDFR
IWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPEL
FVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEI
GTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHA
ATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPDPWKG
SATKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLF
RKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPR
PEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCA
FARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAARD
IFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATILVR
LDTGGQEALQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGGPPP
SWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESSEQQELESLSQDPRRYEE
WKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVLAY
RTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFR
GFWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSREPD
SPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELDEA
GDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGPDTPS
P
NT seq
3606 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggaacccgggcccccctgcggcctggggctgggc
ctgggcctggggctgtgcggcaagcagggccctgcctccccgaactcctctgagcccagc
agggcaccggcacccgtgcccccaccagcaccggaccacagccccccgctcacccggccc
ccggacgggcccaggttccctcgcgtgaagaactgggaggtggggagcatcgcctatgac
accctgagtgcccagtcacagcaggatgggccctgcacccccagacgctgcctgggctct
ctggtatttccacggaaactgcagagccggccgtctcaggaccctccaccccctgagcag
ctgctgagccaggccagggacttcatcaaccagtactatagctctatcaagagaagcggc
tcccaggcccacgagcagaggcttcaggagatggaagctgagatagcggccaagggcacc
taccagcttcgagagagcgagctggtgttcggggccaagcaggcctggcggaatgctccc
cgctgcgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggattgcagc
tctgcccaggagatgttcacctacatctgcaaccacatcaagtatgccaccaaccggggc
aacctccgctcggccatcacagtgttcccccagcgcgccccaggccgcggagacttccga
atctggaacagccaactggtgcgctacgcgggctacaggcagcaggacggctcggtgcgg
ggggacccagccaacgtggagatcacggagctctgcattcagcatggctggaccccagga
aacggccgctttgacgtgctgcccctactgctccaggccccagatgagcccccagaactc
tttgttctgccccccgagctggtcctcgaggtgcccctggagcaccccacgctggagtgg
tttgcggccttgggcctgcgctggtatgccctcccggcggtgagcaacatgctgctggaa
attgggggactggagttccctgcggcccctttcagcggctggtacatgagcactgagatt
ggcacacggaacctgtgtgaccctcaccgatataacatcctggaggatgtggcggtctgc
atggacttggatacccggacaacttcatccctgtggaaagacaaggccgcagtggagatc
aacttggccgtgctgcacagttaccagctggccaaagtgaccatcgtggaccaccatgct
gccactgcctctttcatgaagcacctggagaacgagcagaaggctagggggggctgccct
gccgactgggcctggatcgtgccccccatctctggcagcctcacccctgtcttccatcag
gagatggtcaactatgtcctgtccccggccttccgctatcagccagacccgtggaagggg
agtgcaaccaagggtgccggcatcaccaggaagaagacctttaaagaagtggccaacgca
gtgaagatctctgcctcactcatgggcactgtgatggcaaagcgagtgaaggcgaccatc
ctgtatggctccgagactggccgggcccagagctacgcacagcagctgggtagactcttc
cggaaggctttcgaccctcgggtcctgtgcatggatgagtacgatgtggtgtccctcgag
catgagacgctggtgttggtggtgaccagcacatttgggaatggtgatcccccagagaat
ggagagagttttgcggcggccctgatggagatgtccggcccctacaacagttcccctcgg
ccagaacagcacaagagttacaaaatccgcttcaacagcgtctcctgctcagacccgctg
gtgtcctcctggaggcggaagagaaaggagtccagtaacacagacagtgcaggggccctg
ggcaccctcaggttctgtgtgttcgggctgggatcgcgggcatacccccacttctgcgcc
tttgctcgtgcggtggacacacggctggaggagctgggtggggagcggctgctgcagctg
ggccaaggagatgagctgtgtggccaggaggaggccttccgtggctgggcccaggccgcc
ttccaggcctcctgtgagactttctgcgtgggagaggatgccaaggccgccgcccgggat
atattcagccccaaacggagctggaagcgccagaggtaccggctgagtgcccaggctgag
ggcctccagctgctgccaggcctgatccacgtgcacagaaggaagatgttccaggctaca
gtcctctcagtggaaaacctgcaaagcagcaagtccacccgggccacgatcctggtgcgc
ctagacactggaggccaggaggcgctgcagtaccagcccggcgaccacataggcatctgc
ccgcccaaccggcctggcctcgtggaggcgctgctgagccgtgtggaggatccgcctcca
ccaggagagccagtggcagtggagcagctggagaagggcagccctggtggcccacccccc
agctgggttcgggacccccggctgcccccatgcacactgcgccaggctctcaccttcttc
ctggacatcacttccccgcccagccctcaactccttcgactgctcagcaccctggctgaa
gagtccagtgaacagcaggagctcgagagcctcagccaggacccgcggcgctacgaggag
tggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccctccgtggca
ctacccgcccccctgctcctcacccagctgcccctgctccagccccggtactactcggtc
agctcagcacccagcgcccacccaggagagatccacctcacggtagccgtgctggcatat
aggacgcaggatggactgggcccccttcattacggagtctgctccacatggctaagccaa
ctgaaggccggagatcctgtaccctgcttcatcaggggggccccctccttccggctgccg
cctgatcccagcttgccctgcattctagtgggccctggcacaggcattgcccccttccgg
ggattttggcaggagcggctgcacgacattgacagcaaagggctgcagcccgcccccatg
actttggtgttcggctgccgatgctcccagctcgaccacctttaccgcgacgaggtgcag
gatgcccagcagcgcggagtttttgggcgcgtcctcaccgccttctcccgggagcccgac
agccctaagacctacgtgcaagacatcctgcggacggagctggctgctgaggtgcaccgc
gtgctgtgcctcgaacggggccacatgtttgtgtgcggcgacgtcaccatggcaaccagc
gtcctgcagacggtgcagcgaatcctagcgacggagggcgacatggagctggacgaggcc
ggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacattttcgggctc
acactgcgcacgcaggaggtgacaagccgcatacgcacccagagcttttccttgcaggag
cgacatctgcggggcgcagtgccctgggcgttcgacccgccgggcccagacactcccagc
ccctga
DBGET
integrated database retrieval system
