Arvicanthis niloticus (African grass rat): 117696542
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Entry
117696542 CDS
T08817
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu00310
Lysine degradation
anu01100
Metabolic pathways
anu05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
117696542 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
117696542 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
anu03036
]
117696542 (Dot1l)
Enzymes [BR:
anu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
117696542 (Dot1l)
Chromosome and associated proteins [BR:
anu03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
117696542 (Dot1l)
HMT complexes
Dot1-containing complex
117696542 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
VPS51_Exo84_N
HALZ
Motif
Other DBs
NCBI-GeneID:
117696542
NCBI-ProteinID:
XP_034343380
LinkDB
All DBs
Position
Unknown
AA seq
1731 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAAATEAPVDSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAAS
AERKSKKSQSALDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTQPHSPSPLLVAPTPP
ALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IRRLFQQKLDELGVKALNYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSC
VPPDDALSLHLRGKGALGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAASYEL
CNAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLR
RHLSQDHTGASKAATSEPHPRPEHAKESSLPYQSPGLSNSMKLSPQDPPLASPATSPLTS
EKGSEKGVKERGYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQPRDSSSTLEKQIGTGGAATGSRSLAVAPTGFYAGSVAISGALASSPAPLASGMESA
VFDESSGPSSLFATMGSRSTPPQHPPLLSQPRNSGPASPAHQLTASPRLSVTTQGSLPDT
SKGDLPSDPAFSDPESEAKRRIVFSISAGASSKQSPSTRHSPLTSGTRGDCVQSHGQDSR
KRSRRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLEITAIS
SPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSARIERKI
ATISLESKSPPKTLENGGGLVGRKSVPSSEPVNSSKWKSTFSPISDLGLVKAVDSPLQAG
SALSHSPLFSFRPSLEEPAAEAKLPTHPRKSFASSLGAAEGPSPGTNPPNGLAFSGGLAA
DLGLHSFNDGASLSHKGPDVTGLSASLSFPSQRGKDSATEANPFLSRRQPEGLGSLKGEG
STSKESGESLALCGPSDKASLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGGPG
LVTVASSAGSATPAAQAPRPFLSTFTPGPQFTLGPMSLQASLGSVAGSSVLQSLFSTVPA
AAGLVHVSSTATRLTNSHTMGSFSSGVAGGAVGGVFTHAVPSASAHPFGAGVGSGAVCSS
ATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPNVA
LPPPPALLASNPEPVLLQSLASLPANNAFLPPSSAASLQPANASLSVKLASLPHKVSRPS
FTVHHQPLPRLALAQAAPAAPQASTSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5196 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgcctgtgggcgccgagcccgccgtctac
ccgtggccgctgccggtctacgacaagcaccatgacgctgctcacgagatcatcgagact
atccggtgggtctgcgaggaaatcccagatctcaagctggccatggagaactatgtcctg
atcgactatgacaccaaaagttttgaaagcatgcagaggctgtgtgacaaatacaaccgg
gccatcgacagcatccaccagctgtggaagggcactacacagcccatgaagctgaatacg
cggccgtccaatgggctgctgcggcacatcctgcaacaggtgtacaaccactctgtcact
gacccggagaagctcaacaactatgagcccttctcccctgaggtgtacggggagacctcc
tttgacctggtggcccagatgattgatgagatcaagatgactgaagatgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggtcgctgcggccaccaactgcaaa
catcactacggagtggagaaagcggatatcccagccaagtacgcagagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggaatggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattcgcaaacatg
aaggaaggcggcagaatcgtatcttcaaagccctttgcccctctgaacttcaggatcaac
agcaggaacttgagtgacattggcaccatcatgcgtgtggtggagctgtcgcccctgaag
ggctctgtgtcgtggactggcaagcctgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaggca
gcgaggcgcaggcagcagcgggagaacaagagcaatgctaccacgcccaccaaagtccct
gagagcaaggcagctgccaccgaggcccctgtggattctggtgctgaagaagaaaaatca
ggtgtggccactgtcaaaaagccatctccctccaaagctcggaagaagaaactgaacaag
aaagggagaaagatggctggccggaagcgtgggcgacccaagaaaatgagcgctgccagt
gccgagcgcaagtccaagaagagccagagcgcactggacctccttcactccccaccccca
gccccaccctcagcctcgccccaggatgcctacagggcacctcacagcccgttctaccag
ctacctccgagcacgcagccacactcacccagcccgctgctagtggcccccactccacct
gcgctgcagaagcttttggagtccttcaaaatccagtacttgcagttcctggcttatacg
aagaccccacagtacaaggccaacctacagcagcttctggaccaggagaaggagaagaac
acacagctgctgggcacagcccagcagctcttcggccattgccaggcccaaaaggaagag
atccgcaggctgttccagcagaagctggatgagttgggcgtgaaggcgctgaactacaat
gacctgattcaggcccagaaggaaatctctgcccacaaccagcagctgcgggagcagtcg
gaacagctggagaaggacaacagcgagcttcggagccagagcctgcggctgctcagggcc
cggtgcgaggagctgaggcttgactggtccacactgtccctggagaacctgcggaaagag
aagcaggcccttcgtagccagatctcagagaagcaacggcactgcctggaactgcagatc
agcatcgtggagctcgagaagacccagcgccagcaggaactcctgcagttgaagtcctgt
gtgccaccagatgacgctctgtccctgcatctgcgtggcaagggtgccctgggccgcgag
ctggaggctgacgctgggcgcttacgccttgagctggactgtgccaagatctccctgcca
cacctcagcagcatgagccccgagctgtccatgaatggccatgctgccagctatgagctc
tgcaatgcagctagtcggccctcatccaagcagaacacccctcagtacctggcctccccc
ttggaccaggaggtggtaccctgcacccctagccacagtggccggcctcggctagagaag
ctgtctggcctggctttgcctgactacactcggttgtcacctgccaagattgtgttgagg
cggcacctgagccaggaccacactggggctagcaaagcagctaccagtgagccacaccct
cggccagagcacgccaaggagagcagccttccctaccagagccctggcttgtccaacagc
atgaagcttagtccccaggatccaccgctggcctccccggcaacctcgcccctcacctcc
gagaagggtagtgagaagggggtgaaggagcgtggttacagcagccatggggagaccatc
accagcctgccggttagcattccgctcagcacggtccagcccaacaagctgcctgtcagc
atcccactggccagcgtggtgctgcccagccgggccgagagggcgaggagcactcccagc
cctgtgccacagccccgggactcctcatccacacttgagaagcagattggcacagggggt
gctgcaacaggaagcaggagccttgctgtggcgcccacaggtttttatgctggttcggtg
gccatcagtggggccctggccagcagcccagcacctttggcctctggaatggaatctgct
gtttttgatgagtcctccggccccagcagcctctttgccaccatggggtctcgcagcaca
ccaccacaacacccacctctcctgtcgcagccccgcaattcgggccctgcctctcctgcc
caccaactcacagccagtccccgcctgagtgtgaccacccagggctcgctgccagacacc
agcaaaggggatctgccttctgatcctgccttctcagacccggagagtgaagctaagagg
aggatcgtgttcagcatttcagctggtgccagctccaagcagtcaccttccaccaggcac
agccccttgacctctggcacccgtggggactgtgtacagagccacgggcaggatagtcgc
aaacgcagcagaaggaagcgtgcgtcagctgggacacctagcctcagcacgggcgtgtcc
cccaagcgccgggctctgccaactgttgctggcctctttacacagtcctcggggtctcct
cttaatctcaactccatggtcagcaacatcaaccagcccctggagatcacagccatctca
tcccctgagagctccctgaagagctcccccactccctaccaggaccatgaccagcctccg
gtgctcaggaaggagcggcccctgggaccaactaatggggctcactactcgccactgacc
tcagatgaggagccaggctctgaggatgagcccagcagtgcccgaattgagagaaaaatt
gcaacaatctctttagaaagcaaatctcccccgaagacactggaaaatggtggcggcttg
gtgggaaggaagtcagtcccctcgagcgagcctgtcaacagcagcaaatggaagtccacc
ttctcacccatctccgacctcggcttggtcaaggccgtggacagtccgctgcaggctggc
tctgccctgagccacagccccctgttctctttccggccatccctggaggaacctgctgct
gaggccaagctccccacccacccaaggaaaagctttgccagctctctgggtgcagccgag
ggcccaagccctggcaccaaccctcccaacggcctggccttcagcggaggccttgctgca
gacctcggtttacacagcttcaacgacggtgcttccctctcccacaagggccctgacgtc
actggcctgagtgcttccctgagcttcccatcccagagaggcaaggacagtgccaccgag
gccaaccccttcctcagcaggcggcagccggagggcctgggcagcctgaagggtgagggc
agtacaagcaaggagtcaggagagagcctggccctgtgcgggccctcggacaaggcctca
ctgccccatggcagcagggccagcaaaggccgagaccgcgagctggacttcaagggcggc
cacaacctcttcatctccgctgcagccgtgcctccaggtggcctccttggtggccctggt
cttgtaactgtggcttcctctgcgggcagtgcgacacccgctgcccaggctccccggcct
ttcctgagcaccttcacccctgggccccagtttactctgggccccatgtccctacaggcc
agtctgggttctgtggccggctcctctgtgctgcagtccttgttcagcactgtgccggct
gctgcaggcctggtgcacgtgtcctctactgcgacccgactgaccaactcacacaccatg
ggcagcttctcctctggggtggccggcggagccgttggaggtgtctttacccacgcggtg
ccctccgcctctgctcacccgtttggagctggtgtcggcagcggggctgtgtgtagcagt
gccacactgggcctgagcccgctgcaggcggcggccagcacctcggcttcttcctttcag
gccgcggcttcggtcgagactcggccgccccctccacctcccctacttcctcctcagcat
cttggccggccccctgcggggccacctgtcctccatgcaccccctcctcctaacgtcgcc
ttgcctcctccacctgcgctgctggcttctaaccctgagccagtgcttctgcagagcctg
gcctccctcccggctaacaacgctttcttacccccctcctctgccgcctctctgcagcct
gctaatgcctctctatctgtcaagctcgcctccctcccacacaaggtctcccgcccctcc
ttcacggtgcaccaccagcccctgccccggctggccctggcgcaggccgcgcccgccgcc
ccacaggccagcacctcggggccatctgctgtgtgggtttcccttggcatgccgcctcct
tatgccgcgcacctttcgggggttaagcctcgataa
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integrated database retrieval system
