Actinosynnema pretiosum: CNX65_33160
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Entry
CNX65_33160 CDS
T05092
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
apre
Actinosynnema pretiosum
Pathway
apre00860
Porphyrin metabolism
apre01100
Metabolic pathways
apre01110
Biosynthesis of secondary metabolites
apre01120
Microbial metabolism in diverse environments
apre01240
Biosynthesis of cofactors
Module
apre_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
apre_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
apre00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
CNX65_33160
Enzymes [BR:
apre01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
CNX65_33160
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
CNX65_33160
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ATE57563
UniProt:
A0A290ZF18
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Position
complement(7730458..7731990)
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AA seq
510 aa
AA seq
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MTRARKTPGRVAFVGSGPGDTGLLTVRARDLLGKAELVVTDPDVPAEVVALVPDGVEVRP
AVGEPADVAKDLVAEAKNGAAVVRLVAGDPLTLDSVVKEAHAVSKTTIAFDVVPGVPAGT
AVPAYAGVALGAVHTEADVRGAVDWAGLASATGTLVLHATGGHLAEAASSLVEHGLAPQT
PVAVTADGTGFSQRTVDTTLASLAADAGELSGPLVVTVGSAVANRPKLSWWESRALYGWR
VLVPRTKEQAGAMSDRLHSHGAIPVEVPTISVEPPRSPAQMERSVKGLVDGRYQWVVFTS
TNAVRAVWEKFREFGLDARAFSGVKIACVGEATAAKVRGFGIIPELVPSGEQSSEGLLAD
FPPYDDILDPVDRVLLPRADIATETLAAGLRDRGWEIDDVTAYRTVRAAPPPADTREMIK
SGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPQTAETAREFGLRVDVQPEDANVPA
LVDALAQHAARLRAEGALPPPRKTKRLRRS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcgcgcgcaagacccccggccgagtcgccttcgtgggctccggcccaggtgac
accgggctcctcacggtccgggcccgcgacctgctcggcaaggccgagctggtcgtgacg
gacccggacgtgcccgccgaggtggtcgccttggtccccgacggcgtcgaggtccggccc
gcggtcggcgagcccgccgacgtggcgaaggacctggtggccgaggccaagaacggcgcg
gccgtggtccggctggtcgcgggcgacccgctgaccctggactccgtggtgaaggaggcg
cacgccgtctccaagaccacgatcgccttcgacgtggtccccggcgtgcccgcgggcacg
gccgtccccgcgtacgcgggggtcgcgctgggcgcggtgcacaccgaggccgacgtgcgc
ggcgccgtggactgggccgggctcgcctcggcgacgggcacgctcgtgctgcacgcgacc
ggcggccacctcgccgaggcggcgtcctcgctggtggagcacggcctggccccgcagacc
ccggtcgcggtgaccgccgacggcaccggcttcagccagcgcaccgtcgacaccacgctg
gcctcgctggccgccgacgcgggcgagctgtccggcccgctggtggtcaccgtcggcagc
gcggtcgcgaaccggccgaagctgtcctggtgggagtcgcgggcgctgtacggctggcgc
gtgctggtgcccaggaccaaggagcaggcgggcgcgatgagcgaccggctgcactcgcac
ggcgccatccccgtggaggtgccgacgatctccgtcgagccgccgcgcagcccggcgcag
atggagcgctcggtcaagggcctggtcgacggccgctaccagtgggtcgtgttcacctcg
accaacgcggtgcgcgcggtgtgggagaagttccgcgagttcggcctggacgcccgcgcg
ttctccggcgtgaagatcgcctgcgtcggcgaggccacggcggcgaaggtgcgcggcttc
gggatcatccctgagctggtgccgtccggcgagcagtcctccgagggcctgctggccgac
ttcccgccgtacgacgacatcctggacccggtcgaccgggtgctgctgccgcgcgccgac
atcgccaccgagaccctcgcggccgggctgcgcgaccggggctgggagatcgacgacgtg
acggcctaccgcaccgtgcgggccgccccgccgcccgccgacacccgcgagatgatcaag
tccggcgggttcgacgcggtgtgcttcacctcgtcgtccacggtccggaacctggtcggc
atcgcgggcaagccgcacgcccgcacgctggtggcctgcatcggcccgcagacggcggag
acggcgcgcgagttcggcctgcgcgtggacgtgcagcccgaggacgcgaacgtcccggcg
ctggtggacgcgctggcgcagcacgcggcgaggctgcgcgccgagggcgccctgcccccg
ccgcgcaagaccaagcgcctgcgcaggtcctga
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