Amycolatopsis roodepoortensis: NQK81_20390
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Entry
NQK81_20390 CDS
T08507
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
aroo
Amycolatopsis roodepoortensis
Pathway
aroo00860
Porphyrin metabolism
aroo01100
Metabolic pathways
aroo01110
Biosynthesis of secondary metabolites
aroo01120
Microbial metabolism in diverse environments
aroo01240
Biosynthesis of cofactors
Module
aroo_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
aroo_M00925
Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
aroo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
aroo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NQK81_20390
Enzymes [BR:
aroo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NQK81_20390
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NQK81_20390
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UUV35696
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Position
complement(4342788..4344320)
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AA seq
510 aa
AA seq
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MTPARKTTGRVAFVGSGPGDAGLLTVRAQELLAKAEVVVTDPDVPAGVLAFAAEGAEVRP
AVGEATEVAKDLVNEAKAGRLVLRLIAGDPLTQPAVVAEVQAVSRTSAVFDIIPGVSPGA
AVPAYAGVALGGTHTEVDVRGDVEWAALAATPGPIVLHATSAHLAEAASALTEHGLAPTT
PVAVTSNGTINTQRTLDTTLATVANEAGELVGPLIVTIGQAVGQRSKLSWWESRALYGWK
VLVPRTKEQAGEMAERLRGHGATSHEVPTISVEPPRSPAQMERSVKGLVDGRYQWIVFTS
TNAVRAVWEKFEEFGLDARAFSGVKIACVGESTAAKVRSFGIIPELIPEGEQSSEGLLAE
FPPYDDVLDPVDRVLLPRADIATETLSAGLRERGWEIDDVTAYRTVRAAPPPAETREMIK
TGGFDAVCFTSSSTVRNLVGIAGKPHTRTLVACIGPKTAETAVEFGLRVDVQPEKADVPH
LVDALAEHAARLRAEGALPPPRKAKRARRS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgacccccgcgcgtaagaccaccgggcgtgtcgccttcgtgggctcgggccccggtgac
gccggtctgctgaccgtccgcgctcaggagctgctcgccaaggccgaggtcgtggtgacc
gatccggacgtccctgccggtgtcctggccttcgccgccgaaggtgccgaagtgcgcccc
gccgtcggcgaggccaccgaggtcgccaaggacctggtgaacgaggccaaggccggacgg
ctggtgctccggctcatcgccggtgacccgctgacccagcccgccgtcgtcgccgaggtg
caggccgtttcccggaccagcgccgtgttcgacatcatcccgggcgtctcgcccggcgcg
gccgtcccggcgtatgccggtgtcgctctcggtggcacgcacaccgaggtcgacgtccgc
ggcgacgtcgaatgggccgcactggccgccacccccggcccgatcgtgctgcacgcgacg
tcggcgcacctggccgaggccgcgtccgcgctgaccgagcacgggctggcgccgaccacc
ccggtcgcggtgacgtccaacggcaccatcaacacccagcgcaccctggacaccacgctg
gccaccgtcgcgaacgaggcgggcgagctcgtcggcccgctcatcgtgaccatcggccag
gccgtcggccagcgctcgaagctgtcgtggtgggagtcgcgcgcgctgtacggctggaag
gtcctggtgccgcgcaccaaggagcaggccggtgagatggcggagcggcttcgcggccac
ggcgccacctcgcacgaggtcccgaccatctcggtcgagccgccgcgcagccccgcgcag
atggagcgttcggtcaagggtctcgtcgacggccgctaccagtggatcgtcttcacctcg
accaacgccgtccgcgcggtgtgggagaagttcgaggagttcggcctcgacgcccgtgcc
ttctcgggcgtgaagatcgcctgcgtcggcgaatcgaccgccgcgaaggtgcgctccttc
ggcatcatcccggagctgatcccggagggcgagcagtcctcggagggcctcctcgccgag
ttcccgccgtacgacgacgtcctcgacccggtcgaccgcgtgctgctgccgcgggcggac
atcgccaccgagaccctttcggcaggcctgcgcgaacgcggctgggagatcgacgacgtg
accgcgtaccgcaccgtccgggccgccccgccgcccgccgagacccgcgagatgatcaag
accggcggtttcgacgcggtctgcttcacctcgtcctcgaccgtgcggaacctcgtcggc
atcgccggcaagccgcacactcgcacgctggtcgcgtgcatcggcccgaagaccgcggag
accgccgtggagttcgggctgcgggtcgacgtccagcccgagaaggccgacgtcccgcac
ctggtcgacgcgctcgccgagcacgccgcccggctccgtgccgaaggcgcgcttccgccg
ccgcgcaaggcgaagcgggcccgccgctcctga
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