Amycolatopsis thermalba: L1857_04870
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Entry
L1857_04870 CDS
T08681
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
athm
Amycolatopsis thermalba
Pathway
athm00860
Porphyrin metabolism
athm01100
Metabolic pathways
athm01110
Biosynthesis of secondary metabolites
athm01120
Microbial metabolism in diverse environments
athm01240
Biosynthesis of cofactors
Module
athm_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
athm_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
athm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
L1857_04870
Enzymes [BR:
athm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
L1857_04870
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
L1857_04870
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UQS22200
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Position
965163..966698
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AA seq
511 aa
AA seq
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MTPARTTAGRVAFVGSGPGDAGLLTVRAQELLAKAEVVVTDPDVPAGVLAGASADAEVRP
AVGEPAEVAKDLANEAKGGRLVLRLSSGDPLTSAAAVAEVQAVAKTSAVFEVVPGITPGS
AVPAYAGIALGGSYTDVDVRGDVDWAKVAAAPGPIVLHATSGQLAEAAGALTEHGLAGTT
PVAVTANGTINTQRTVDTTLASLSQDAGELVGPLVVTVGEQAGQRSKLSWWESRALYGWK
VLVPRTKEQAGEMAERLRIHGATSHEVPTISVEPPRSPAQMERAVKGLVDGRYQWIVFTS
ANAVKAVWEKFEEFGLDARAFSGVKIACVGEATAARVRAFGINPEMIPQGEQSSEGLLAE
FPPYDDVLDPVNRVLLPRADIATETLSAGLVDRGWEVDDVTAYRTVRAAPPPAETREMIK
TGGFDAVCFTSSSTVRNLVGIAGKPHTRTLVACIGPKTAETAVEFGLRVDVQPEVADVPH
LVDALAAHAAKLRAEGALPPPRKAKRTRRSS
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
atgacccccgcgcggacaaccgctgggcgcgtcgccttcgtgggctccggccccggcgac
gccggactgctgaccgtacgtgcccaggagctcctggcgaaggccgaggtcgtggtgacc
gacccggacgtgcccgccggcgtgctcgcgggcgccagcgcggacgccgaggtccggccc
gccgtcggcgagccggccgaggtcgcgaaggacctcgccaacgaggccaagggcggacgg
ctggtgctgcgcctgtccagcggtgacccgctgaccagcgccgccgccgtcgccgaggtg
caggccgtggcgaagaccagcgcggtcttcgaggtcgtccccggcatcacgccgggctcg
gccgtgcccgcctacgccggcatcgcgctcggcggcagctacaccgacgtggacgtccgc
ggtgacgtggactgggcgaaggtggccgcggcgccgggcccgatcgtgctgcacgcgacg
tccggccagctggccgaggccgcgggcgcgctgaccgagcacggcctggccggcaccacc
ccggtcgccgtgaccgccaacggcacgatcaacacccagcgcacggtcgacaccacgctg
gcgagcctgtcgcaggacgccggtgagctggtcggaccgctcgtggtgaccgtcggtgag
caggccgggcagcggtcgaagctgtcctggtgggagtcgcgtgccctgtacggctggaag
gtcctggtgccgcgcaccaaggagcaggccggcgagatggccgagcggctgcgcatccac
ggcgccacctcgcacgaggtgccgaccatctcggtcgagccgccgcgcagccccgcgcag
atggagcgcgcggtcaagggcctggtcgacggccgctaccagtggatcgtgttcacctcg
gccaacgcggtgaaggcggtgtgggagaagttcgaggagttcggcctcgacgcccgcgcc
ttctccggcgtgaagatcgcctgcgtcggcgaggccaccgcggcgcgcgtgcgggcgttc
ggcatcaacccggagatgatcccgcagggcgagcagtccagcgagggtctgctggccgag
ttcccgccgtacgacgacgtgctggacccggtgaaccgcgtgctgctgccgcgggccgac
atcgccaccgagaccctgtccgcgggcctggtggaccgcggctgggaggtcgacgacgtg
acggcctaccggaccgtccgggccgcgccgccgccggccgagacgcgcgagatgatcaag
accggcgggttcgacgcggtgtgcttcacctcgtcctcgacggtgcggaacctggtcggc
atcgccgggaagccgcacacgcgcacgctggtggcgtgcatcgggccgaagaccgcggag
accgcggtggagttcggcctgcgggtggacgtgcagccggaggtggccgacgtgccgcac
ctggtcgacgcgctggccgcgcacgccgcgaagctgcgcgcggagggcgccctgccgccg
ccccggaaggcgaagcgcacgcggcgttcttcctga
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