Amycolatopsis thermalba: L1857_10280
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Entry
L1857_10280 CDS
T08681
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
athm
Amycolatopsis thermalba
Pathway
athm00290
Valine, leucine and isoleucine biosynthesis
athm00660
C5-Branched dibasic acid metabolism
athm01100
Metabolic pathways
athm01110
Biosynthesis of secondary metabolites
athm01210
2-Oxocarboxylic acid metabolism
athm01230
Biosynthesis of amino acids
Module
athm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
athm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
L1857_10280 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
L1857_10280 (leuC)
Enzymes [BR:
athm01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
L1857_10280 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
L1857_10280 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
UQS23176
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Position
2077558..2078973
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AA seq
471 aa
AA seq
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MTTTRPRTLAEKVWEAHTVRRGEGAEPDLLYIDLHLVHEVTSPQAFDGLRLAGRKVRRPD
LTIATEDHNVPTVDIELPIADPVSRTQVETLRKNCAEFGVRLHPMGDAEQGIVHVIGPQL
GLTQPGMTVVCGDSHTSTHGAFGAMAFGIGTSEVEHVLATQTLPLRPFKTMAINVDGQLR
PGVTAKDVILAVIAKIGTGGGQGYVLEYRGSAIEALSMEARMTICNMSIEAGARAGMIAP
DETTFAYLKGRPHAPKGADWDAAVENWKSLRTDEGAEFDAEVHLDADTLTPFVTWGTNPG
QGLPLSESVPDPEQIADENERYAAEKALSYMDLKPGTPLREIKVDTVFLGSCTNGRIEDL
RAAADVLQGRKVAQGVRMLVVPGSMRVRQAAEAEGLDKVFLDAGAEWRQAGCSMCLGMNP
DQLAPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLN
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccacgcggccgcggacactggccgagaaggtgtgggaggcgcacacggtgcgc
cgcggtgaaggagcggaacccgacctgctctacatcgacctgcacctggtgcacgaagtc
accagcccgcaggcgttcgacggtctccgcctggcggggcgcaaggtgcgccgcccggat
ctgaccatcgcgaccgaggaccacaacgtcccgaccgtcgacatcgaactcccgatcgcc
gacccggtgtcccgcacccaggtcgagacgcttcggaagaactgcgcggagttcggcgtc
cggctgcacccgatgggcgacgccgagcagggcatcgtgcacgtcatcggcccgcagctg
ggcctgacccagcccggtatgacggtcgtgtgcggtgacagccacacctccacccacggc
gccttcggcgcgatggcgttcggcatcggcacctccgaggtcgagcacgtgctggccacc
cagaccctgccgctgcggccgttcaagacgatggcgatcaacgtggacggacagctccgc
ccgggcgtcaccgcgaaggacgtcatcctcgctgtcatcgccaagatcggcaccggcggc
ggccagggctacgtcctggagtaccggggcagcgcgatcgaggcgctgtcgatggaagcc
cggatgaccatctgcaacatgtcgatcgaggcgggcgcccgcgccggcatgatcgccccg
gacgagaccaccttcgcctacctgaagggccgcccgcacgccccgaagggcgccgactgg
gacgccgcggtcgagaactggaagtcgctgcgcaccgacgagggcgccgagttcgacgcc
gaggtccacctcgacgccgacaccctgaccccgttcgtgacctggggcaccaaccccggc
cagggcctgccgctgagcgagtcggtgccggacccggagcagatcgccgacgagaacgag
cggtacgccgccgagaaggccctgtcctatatggacctgaagccgggcacgccgctgcgg
gagatcaaggtcgacaccgtcttcctcggctcgtgcaccaacggccggatcgaggacctg
cgggccgccgcggacgtgctccagggccgcaaggtggcgcagggcgtccggatgctcgtc
gtgcccggctcgatgcgggtgcgccaggccgccgaggccgaggggctggacaaggtcttc
ctcgacgccggcgccgagtggcggcaggcgggctgctcgatgtgcctgggcatgaacccg
gaccagctggcccccggcgagcgcagcgcctccacctccaaccgcaacttcgagggcagg
cagggcaagggtggccgcacccacctcgtctcgccgctcgtcgcggccgccacggccgtc
cgcggcacgctgtccagccccgaagacctgaactga
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