Actinocatenispora thailandica: Athai_56910
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Entry
Athai_56910 CDS
T07045
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
atl
Actinocatenispora thailandica
Pathway
atl00860
Porphyrin metabolism
atl01100
Metabolic pathways
atl01110
Biosynthesis of secondary metabolites
atl01120
Microbial metabolism in diverse environments
atl01240
Biosynthesis of cofactors
Module
atl_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
atl_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
atl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Athai_56910 (hemD)
Enzymes [BR:
atl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Athai_56910 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Athai_56910 (hemD)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BCJ38188
UniProt:
A0A7R7DUQ5
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All DBs
Position
complement(6262006..6263589)
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AA seq
527 aa
AA seq
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MTRARKSVGRITVVGAGPGDPGLLTRRAAEAVAAADHVVYDRSVPEVLLSAVLSEGAERS
PAEGAPGDIAKVLLSAARSGLSAVRLVAGDPYGHDSVVKEIQAVSRSAVPFEVVPGISHA
SAVASYAGMPPGPVRTEVDADDVVNLDFDAVAAALGGAGDQSSLALTVDAGSLAQVRDGL
LAAGVDGGVPVAVTGDGTGETQYTTSSTVDSFVEAALGFGGPVVLTLGGGVPQRDKLGWW
ENRPLYGWKVLVPRTKEQAGAMSARLRVYGAIPSEVPTIAVEPPRTPAQMERAIKGLVDG
RYAWIVFTSTNAVRAVWEKFAEHGLDARHFGGVKIACIGDATAEAVRSFGIQPELVPDGE
QSSDGLLAEFPPFDDVLDPVGRVLLPRADIATETLAAGLVERGWEVDDVTAYRTVRAAPP
PADIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVACIGPKTAETAVEFGLRVDV
QPEHASITDEVEALAEYAVELKEKLAQMPPKQRRGSKVQGPSALRFR
NT seq
1584 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcgcgcgtaagtccgtcggccgcatcaccgtggtgggcgccggtcccggtgac
ccgggcctgctcacccggcgtgcggcggaggcggtggccgcagccgaccacgtggtgtac
gaccggtcggtgcccgaagtcctgctgtccgccgtgctgtccgagggggcggagcgcagc
cccgccgagggggcgcccggcgacatcgccaaggtgctgctgtccgcggcccggtccggg
ctgtccgcggtccggctggtggccggcgacccgtacgggcacgactcggtggtgaaggag
atccaggcggtgtcgcgcagcgcggtgccgttcgaggtggtgccggggatcagtcacgcc
tccgcggtcgcctcgtacgcgggcatgccgcccggcccggtgcggaccgaggtggacgcg
gacgacgtggtcaacctcgacttcgacgcggtggcggcggcgctcggcggggccggcgac
cagtcctcgctcgcgctgaccgtggacgccggcagcctcgcgcaggtacgcgacgggctg
ctcgccgcgggcgtcgacggcggtgttccggtggcggtgaccggtgacggcaccggcgag
acgcagtacaccacgtcgtccactgtggacagttttgtggaggcggcgctcggcttcggc
ggcccggtggtgctgaccctgggcggcggcgtaccgcagcgcgacaagctcggctggtgg
gagaaccgcccgctgtacggctggaaggtcctggtgccgcgcaccaaggagcaggccggc
gcgatgtccgcccggctccgggtgtacggcgcgatcccgtccgaggtacccaccatcgcc
gtcgaaccgccgcgtaccccggcgcagatggagcgggcgatcaagggcctggtcgacggc
cggtacgcgtggatcgtcttcacctccaccaacgcggtgcgcgcggtgtgggagaagttc
gccgagcacggcctggacgcccggcacttcggcggcgtcaagatcgcctgcatcggcgac
gcgaccgccgaggcggtccgcagcttcggcatccagcccgagctggtgccggacggcgag
cagtcctccgacggcctgctcgccgagttcccgccgttcgacgacgtgctcgacccggtg
ggccgggtgctgctgccgcgcgccgacatcgccaccgagacgctcgccgccggcctggtc
gagcgcggctgggaggtcgacgacgtcaccgcctaccgcacggtgcgggcggcgccgccg
ccggccgacatccgggacgcgatcaagtccggcgggttcgacgcggtcctgttcacctcg
tcctccacggtgcgcaacctggtcggcatcgccggcaagccgcacgcccgtacggtcgtc
gcctgcatcgggccgaagaccgcggagaccgccgtcgagttcgggctgcgggtcgacgtg
cagccggagcacgcgtcgatcaccgacgaggtcgaggcgctcgccgagtacgcggtcgag
ctgaaggagaagctcgcccagatgccgcccaagcagcgccgcggctcgaaggtgcagggc
ccgtcggcgctgcggttccgctga
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