Actinomyces viscosus: NCTC10951_00393
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Entry
NCTC10951_00393 CDS
T06789
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
avc
Actinomyces viscosus
Pathway
avc00290
Valine, leucine and isoleucine biosynthesis
avc00660
C5-Branched dibasic acid metabolism
avc01100
Metabolic pathways
avc01110
Biosynthesis of secondary metabolites
avc01210
2-Oxocarboxylic acid metabolism
avc01230
Biosynthesis of amino acids
Module
avc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
avc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NCTC10951_00393 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NCTC10951_00393 (leuC)
Enzymes [BR:
avc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NCTC10951_00393 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NCTC10951_00393 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
VEI14527
UniProt:
A0A3S4V8V0
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Position
1:422811..424349
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AA seq
512 aa
AA seq
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MGMTLAEKVWRDHVVSKGSDGAPDLLFIDLHLVHEVTSPQAFEGLRLAGREVRRTDLTIA
TEDHNTPTLDIDLPIADVTSRAQIETLRANCAEFGVRLHSLGDADQGIVHAVGPQLGLTQ
PGMTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPIAPFKTMSVTIDGDLPSGSG
AKDIILAIIAKIGTNGAQGHVIEYRGRAIEQLSMEARMTICNMSIEGGARAGMIAPDQTT
FDYLKERPHAPVGEDWDAAVEYWSSLRTDPDAVFDTEVVLEAKDIEPFVTWGTNPGQGLP
LSATVPDPEDIADATERLAAERALEYMDLVPGTPLRDIKVDTVFIGSCTNGRIEDLRAAA
EVVRGRKKADGLRMLVVPASARVRLQAEAEGLDRVFKSFGAEWRNAGCSMCLAMNPDKLS
SGERAASTSNRNFEGRQGKGGRTHLVSPVVAAATAVRGALSAPGDLPPRPAGWEESDAVD
DGPALGADDIPVVTAVPPVPQPASIMLPVTVL
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgactctcgccgagaaggtctggcgtgatcatgtggtgtccaaggggagcgac
ggcgcccccgacctgctgttcatcgaccttcacctggttcacgaggtcaccagcccccag
gccttcgaggggctgcgtctggccggccgcgaggtgcgtcgcaccgacctgaccatcgcc
accgaggaccacaacacccccaccctggacatcgacctgccgatcgccgacgtcaccagc
cgcgcgcagatcgagaccctgcgggccaactgcgccgagttcggggtgcgcctgcactcg
ctgggggatgccgaccaggggatcgtccacgccgtcggcccgcagctggggctgacccag
cccggcatgaccgtcgtctgcggcgactcccacacctccacccacggagccttcggggcg
ctcgccttcggcatcggcacctcccaggtcgagcacgtcttggcgacccagaccctgccc
atcgcccccttcaagacgatgagcgtcaccatcgacggcgacctgccctcgggcagcggg
gccaaggacatcatcctggccatcatcgccaagatcgggaccaacggcgcccaggggcat
gtcatcgagtaccgcggccgcgccatcgagcagctctcgatggaggcccgcatgacgatc
tgcaacatgagcatcgagggcggggcccgggccggcatgatcgcccccgaccagaccacc
ttcgactacctcaaggagcgtccccacgcgcccgtcggcgaggactgggacgccgccgtg
gagtactggtccagtctgcgcaccgaccccgacgccgtcttcgacaccgaggtggttctc
gaggccaaggacattgagcccttcgtcacctggggcaccaaccccgggcagggcctgccg
ctgtccgccacggtccccgaccccgaggacatcgccgacgccaccgagcggctcgccgcc
gagcgggccctggagtatatggatctcgtcccggggacgccgctgcgcgacatcaaggtc
gacaccgtcttcatcggctcgtgcaccaacggccgcatcgaggacctgcgggccgccgcg
gaggtggtgcgcggacgcaagaaggctgacggactgcgcatgctcgtggtgccggcctcc
gcccgggtgcggctgcaggccgaggccgagggcctggaccgggtcttcaagagcttcggc
gccgagtggcgcaacgccggctgctccatgtgcctggccatgaacccggacaagctctcc
tccggggagcgcgccgcctccacctccaaccgcaacttcgaggggcgccagggcaagggc
ggacgaacccacctggtctctcccgtcgtcgccgcggccaccgccgtgcgcggggccctg
tccgccccgggggacctgcctccgcggcccgccggctgggaggagtccgacgccgtcgat
gacggcccggccctgggggccgacgacatcccggtggtcacggcggttccgccggtgccg
cagccggcgtccatcatgctcccggtgaccgtgctgtag
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