Bacillus anthracis Ames Ancestor: GBAA_1422
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Entry
GBAA_1422 CDS
T00178
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
bar
Bacillus anthracis Ames Ancestor
Pathway
bar00290
Valine, leucine and isoleucine biosynthesis
bar00660
C5-Branched dibasic acid metabolism
bar01100
Metabolic pathways
bar01110
Biosynthesis of secondary metabolites
bar01210
2-Oxocarboxylic acid metabolism
bar01230
Biosynthesis of amino acids
Module
bar_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
GBAA_1422 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
GBAA_1422 (leuC)
Enzymes [BR:
bar01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
GBAA_1422 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
GBAA_1422 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AAT30518
UniProt:
Q81T66
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All DBs
Position
1346332..1347726
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AA seq
464 aa
AA seq
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MGKRLLDKLWERHVVTTNENGLDLLYIDLHLVHEVTSPQAFEGLRLTNRTVRRPDLTFAT
MDHNIPTKDVWNITDRIAKQQLDTLRENCKQFQVPLADIGDEEQGIVHVIGPELGLTQPG
KTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPKAMGIELKGKLQKGVYAK
DIILHLLSKYGVAVGTGYVMEFYGETIGTMEMEERMTLCNMAIEGGAKAGIIAPDEKTFA
YVKGRKYAPRDYETFEKKWFELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRIDEK
LPEKHDVNDERAFSYMGLIPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASVVKGRKVKEG
VRALVVPGSKRVRDAAMQKGLHHIFEEAGFEWREPGCSMCLGMNPDQVPEGEHCASTSNR
NFEGRQGKGARTHLVSPAMAAAAALYGHFVDIRKESYDGAISYS
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atggggaaaaggttgctagataagctttgggaaagacacgtagttacgaccaacgaaaat
ggattggatttattatatatcgatctgcatcttgttcatgaagtaacgtcaccgcaagcc
tttgaaggcttgcggcttacaaatcgaacggtacgcagaccagatttaacattcgcaacg
atggatcataatattccaacgaaagatgtttggaatattaccgatcgcattgcgaagcag
caactagatacgcttcgggaaaattgtaaacaatttcaggtgccgttagcggatatcggg
gatgaagagcaagggatcgttcatgttatcggaccagaacttgggctcacgcagccagga
aaaacaattgtttgtggtgatagtcatacagcaacgcacggtgcgtttggcgcgctagca
tttggcattggtacgagtgaagtggaacatgtattggcaacgcaaacgttgtggcaaaga
aaaccgaaagcgatgggaattgagttaaaaggaaaattacagaaaggcgtttacgcaaaa
gatattattttgcatctcctttcaaagtacggtgtagcagttggaactggatacgtaatg
gaattttacggagagacgattgggaccatggagatggaagagagaatgacgctttgtaat
atggcgattgaaggaggagcaaaagcgggtattatcgcaccagatgaaaaaacatttgct
tatgtaaaaggacgtaaatatgcaccgagagactatgaaactttcgagaagaaatggttt
gaactgtatacagatgcagatgcaatttatgatttacatatttcgatagatgttacggat
ttagcgccgtatgttacgtggggaacgaacccgagtatgggagttcgtattgatgagaaa
ttgccagaaaagcatgatgtaaatgacgaaagagcattctcttatatgggattaatccct
ggacaaagtacgtatgacattccagttcagcatgtcttcattggatcttgtacaaattct
agattatctgatttagaaattgctgcatctgttgtgaaagggagaaaggtaaaagaaggt
gtgcgagcactcgttgtacctggatcgaaaagagtaagggatgcggcgatgcaaaaagga
ctacatcacatatttgaagaagctggatttgaatggagagaacctggatgttccatgtgt
cttggaatgaatccagatcaagtacctgaaggagagcattgtgcttcaacttcaaatcgt
aattttgaaggaagacaaggaaaaggagcacgaacgcatttagttagcccagcaatggcg
gcagcagctgcgttatatggtcattttgttgatattagaaaggagagttatgatggagcc
atttcgtattcataa
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