Bison bison bison (American bison): 105000870 Help Entry 105000870         CDS       T08726                                  Symbol TSC1 Name (RefSeq) hamartin   KO K07206   tuberous sclerosis 1 Organism bbis  Bison bison bison (American bison) Pathway bbis04072   Phospholipase D signaling pathway bbis04140   Autophagy - animal bbis04150   mTOR signaling pathway bbis04151   PI3K-Akt signaling pathway bbis04152   AMPK signaling pathway bbis04211   Longevity regulating pathway bbis04218   Cellular senescence bbis04714   Thermogenesis bbis04910   Insulin signaling pathway bbis05163   Human cytomegalovirus infection bbis05165   Human papillomavirus infection bbis05168   Herpes simplex virus 1 infection bbis05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     105000870 (TSC1)    04151 PI3K-Akt signaling pathway     105000870 (TSC1)    04152 AMPK signaling pathway     105000870 (TSC1)    04150 mTOR signaling pathway     105000870 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     105000870 (TSC1)   09143 Cell growth and death    04218 Cellular senescence     105000870 (TSC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105000870 (TSC1)   09149 Aging    04211 Longevity regulating pathway     105000870 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     105000870 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     105000870 (TSC1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     105000870 (TSC1)    05163 Human cytomegalovirus infection     105000870 (TSC1)    05165 Human papillomavirus infection     105000870 (TSC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  105000870 NCBI-ProteinID:  XP_010855241 Ensembl:  ENSBBBG00000009854 UniProt:  A0A6P3ILR9 LinkDB All DBs Position Unknown AA seq 1148 aa AA seqDB search MAQQANIGELLSMLDSPLLSVRDDVTTVFKENLNSDRGPMLVNTLVDYYLETNSQPVLHI LTTLQEPHDKHLLDKMNEYVGKAASRLSALLLLGHVVRLQPSWKHKLSQAPLLPSLLKCL KMDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEVYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECYEDGYSVSHQISARFPHRSADVSASSYVDTQNSYGNATSTP YSTCRLTLNTPGQLPQTLSSPSTRLLAEPPQATLWSPSAVCGMTTPPTSPGNVPPDLSHP YSKVFGTTGGKGTPLGTPATSPPPAPPCHSDDCVHLSLPQATAPKKEERTDSARPCLHRQ PHVPNDRGLEELHGGKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISKELSEITTADAE PLVPRGGFDSPFYRDSLPGCPRKTLSASSSTQGTSANPEPLNSSLDKSGPDTPKQAFTPI DLPCGGTGESPAGNRERQASLEASILTPSPCKIPPQRGVGFGSGQPPPYDHLFEVALPKT AHHFVSKKTEELLKKAKGSAEEDFTPSASPMEVLDRLIQQGADVHSKELNRLSLPSKSVD WTHFGGSPPSDEIRTLRNQLLLLHNQLLYERFKRQQHALRNRRLLRKVIRASALEEHNAA MKDQLKLQEKDIQIWKISLQKEQARYNQLQEQRDTVVTQLHSQIRQLQHDREEFYNQSQE LQTKLEDCRNMIAELRVELKKANSKVCHTELLLSQVSQKLSNSESVQQQMEFLNRQLLVL GEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQNQRLDTCQKRILELESH LAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELEILDLYGKLEKDGLL KKLEEQKPEAAEAAEERLDYCQDGCSDSVTGHNEEAPGRNGETKPSRPGGARGGGGGGGR GGGSSSELSTPEKPPNPRAGPFSSRWEMVVGEPTSGTPTTVGSLPSSESFLGMKARELFR NKSESQCDEDGLTVGSLSETLKTELGKDSGVEARAPLTLDGPLLPAQKPDSVGQLRIMDY NEAQLEHS NT seq 3447 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagccaatattggggagctcctctccatgctggactcccctctgctgagt gtgcgtgatgatgtaacaactgtctttaaagagaatctcaattctgaccgtggtcctatg cttgtgaacaccctggtggattattatctggaaaccaactctcagcctgtattgcacatc ctgactaccttgcaagagccccatgataagcacctcttggacaaaatgaatgaatacgtg ggcaaggccgcctctcggttatccgccctcttgctactgggccacgtcgtgaggctgcag ccgtcatggaagcataagctctctcaagcacctcttttgccttctctactaaaatgtctc aagatggacaccgacgtcattgtcctcacaacaggagtcttagtgttgataaccatgctc ccaatgattccgcagtcggggaaacagcaccttcatgatttctttgatatctttggccgt ctttcgtcatggtgcctgaagaaaccaggccatgtgacagaagtctatctcgtccacctc cacgccagcgtctacgctctcttccatcgcctgtatgggatgtacccttgcaactttgtc tcctttctgcgttctcactacagtatgaaggaaaacctggagacttttgaagaagtggtc aagccaatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccat gaactggaccctcgaaggtggaagagattagaaacacatgatgttgtcatagaatgttat gaagatggctattctgtgtctcaccaaatctcagcccgttttcctcaccgttcagccgat gtctccgccagctcttacgttgacacacagaatagctatgggaatgctacttctaccccc tactctacttgtcggctgacgttaaacacgccagggcagctacctcagactctgagttcc ccgtcgacacggctattagctgagccgccacaagctactctttggagcccatctgcagtt tgtgggatgaccactcctccaacttctcctggaaatgtcccacctgatctgtcacatcct tacagtaaagtctttggtacaactggtgggaaaggaactcctctgggaacccctgcaacc tctcctcctccagccccaccctgccattcggacgactgcgtgcacctttcactcccacag gccacggcccccaagaaggaagagaggacagactccgcaaggccctgtctacacagacaa ccccatgttccgaatgacagaggattagaagagctgcacggaggcaagggatctgtcact ctcagtgatcttccagggtttttaggagacctggcttctgaagaagacagtattgagaag gataaagaagaagcggccatatctaaagagctgtctgagatcacgacggccgatgccgag cccctggttcctcgaggaggcttcgactcacccttctaccgggacagtctgccgggctgc ccgcggaagaccctctcagcttcctccagcactcagggcaccagcgcgaaccctgagcct ttaaactcctccctggacaagtcggggcctgacacaccaaagcaagccttcacgcccata gacctgccctgcggaggcaccggggagagccctgccgggaacagggagcgccaggcctct ctggaggccagcatcctcacccccagcccctgtaaaattccacctcagaggggagtgggg tttggcagtgggcagcctcccccatacgatcatctttttgaggtggcattgccaaagact gcccatcattttgtcagcaagaagacggaggaactactcaagaaggcaaagggaagtgca gaggaggacttcacgccctccgcctcccctatggaagtgctggacaggctgatacagcag ggagcggacgtgcacagcaaggagctcaacaggttgtctttacccagcaagtctgtcgac tggacccacttcggaggctctcctccctcagatgagatccgcaccctccgtaaccagttg cttttactgcacaaccagttactctacgagcgtttcaagcggcagcagcacgcgctgcgc aacaggcggctcctgcgcaaggtgatccgggcctcggctctggaggagcacaacgccgcc atgaaagaccagttgaagttgcaagagaaagacatccagatatggaagattagtctgcag aaagaacaagccaggtacaatcagcttcaggagcagcgagacacagtggtcacccagctt catagccagatcagacagcttcagcacgaccgggaggagttctacaaccagagccaggag ttacagacgaagctggaggactgcaggaacatgatcgcagagctgcgcgtggagctgaag aaggccaacagcaaggtgtgccacaccgagctgctgctcagccaggtgtcccagaagctc tcaaatagtgagtcggtccaacagcagatggagttcttgaacaggcaactgttggttctt ggggaagtcaacgagctgtatttggaacagctgcagaacaagcattcagacaccaccaag gaagtagaaatgatgaaggctgcgtatcggaaagagctagaaaaaaacagaagccacgtc ctccagcagaatcagaggcttgatacctgtcagaagcggattttggaactggaatctcat ctggctaagaaagaccaccttcttttagaacagaaaaagtatctagaggatgtcaaactg caggcaagaggacagctacaggctgcagagagcaggtatgaggcccaaaagaggatcacc caggtgtttgaattggagatcttagatttatacggcaagttggagaaggatggcctcctg aaaaaacttgaagaacaaaaaccagaagcagctgaagcagcagaagaaaggcttgactac tgtcaggacggctgctcggattcggtgacagggcacaacgaagaggcccctggccgtaac ggtgagaccaagccctccaggcctggcggcgcccggggcggtggcggtggcggcggcaga ggtggcggcagcagcagcgagctctccaccccggagaagccccccaaccccagggcgggc ccgttcagcagtcggtgggagatggtggtgggtgagcccacttccggcacccccacgacg gtgggctcgcttcccagctcagagagcttcctgggcatgaaggcacgagagctgtttcgt aacaagagcgagagccaatgcgacgaggatggcctgactgttggcagcctttctgagacc ctaaagacagagctgggcaaagactcgggtgtggaagccagggcccccctgacccttgat ggcccactgctgcctgcccaaaagccggacagcgtgggccagctccgcatcatggactac aacgaggcccagcttgagcacagctag

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