Burkholderia cepacia GG4: GEM_5581
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Entry
GEM_5581 CDS
T02205
Name
(GenBank) squalene-hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
bct
Burkholderia cepacia GG4
Pathway
bct00909
Sesquiterpenoid and triterpenoid biosynthesis
bct01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
bct00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
GEM_5581
Enzymes [BR:
bct01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
GEM_5581
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
GEM_5581
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Pec_lyase
TED_complement
Motif
Other DBs
NCBI-ProteinID:
AFQ51965
UniProt:
A0A9W3K827
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All DBs
Position
2:2642246..2644219
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AA seq
657 aa
AA seq
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MNDLTDMATLSAGTAPAGLDAAVASATDALLAAQNADGHWVYELEADSTIPAEYVLLVHY
LGETPNLELEQKIGRYLRRIQQADGGWPLFTDGAPNISASVKAYFALKVIGDDENAEHMQ
RARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWAR
TVIVPLLVLNAKRPLAKNPRGVRIDELFIDPPVNAGLLPRQGHQSAGWFAFFRVVDHALR
AVDGLFPSYTRERAIRQAVSFVDERLNGEDGLGAIYPAMANAVMMYDVLGYAEDHPNRAI
ARKAVEKLLVVHEDEAYCQPCLSPVWDTSLAAHALLETGDVRAEEAVLRGLDWLLPLQIL
DVRGDWISRRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLKQTDTYRESMARAR
EWVVGMQSSDGGWGAFEPENTQYYLNNIPFSDHGALLDPPTSDVSGRCLSMLSQLGESAL
TSEPARRALDYMLKEQEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPDDPRMKRGAQWL
LSIQNKDGGWGEDGDSYKLNYRGFEQAPSTASQTAWALLGLMAAGEVNNPAVARGVDYLI
ARQNEEGLWDETRFTATGFPRVFYLRYHGYRKFFPLWALARYRNLKRANATRVTVGM
NT seq
1974 nt
NT seq
+upstream
nt +downstream
nt
atgaacgatctcaccgatatggctaccctgtccgccggcaccgcgccggccgggctcgac
gcggccgtcgccagcgcgaccgacgcgctgctggccgcgcagaacgcggacggacactgg
gtctacgaactcgaggccgattcgacgattcccgccgaatacgtgctgctcgtccactat
ctcggcgagacgccgaacctcgagctcgaacagaagatcggccgctatctgcgccgcatc
cagcaggcggacggcggctggccgctgttcaccgacggcgcgccgaacatcagcgcgagc
gtgaaggcgtatttcgcgctgaaggtgatcggcgacgacgagaacgccgagcacatgcag
cgcgcgcgccgcgcgatccacgcgatgggcggcgccgagatgtcgaacgtgttcacgcgg
atccagctcgcgctgtacggcgcgattccgtggcgtgcggtgccgatgatgccggtcgag
atcatgctgctgccgcagtggttcccgttccacctgtcgaaggtctcgtactgggcgcgt
accgtgatcgtgccgctgctggtgctgaacgcgaagcgcccgctcgcgaagaacccgcgc
ggcgtgcgcatcgacgagctgttcatcgacccgcccgtcaacgctggcctgctgccccgc
cagggccaccagagcgccggctggttcgcgttcttccgggtggtcgaccatgcgctgcgc
gcggtcgacgggctgttcccgagctacacgcgcgaacgcgcgatccgccaggccgtgtcg
ttcgtcgacgagcgcctgaacggcgaggacggcctcggcgcgatctatccggcgatggcc
aacgcggtgatgatgtacgacgtgctcggctatgcggaagaccatccgaaccgcgcgatc
gcgcgcaaggcggtcgagaaactgctcgtcgtccatgaggacgaagcgtattgccagccg
tgcctgtcgccggtgtgggacacgtcgctcgccgcgcacgcgctgctcgaaaccggcgat
gtacgcgccgaggaagccgtgctgcgcggcctcgactggctgctcccgctgcagatcctc
gacgtgcgcggcgactggatctcgcgccgcccgaacgtgcgtcccggcggctgggcattc
cagtatgcgaacgcgcactatccggacgtcgacgacacggccgtcgtcgtgatggcgatg
gaccgcgcgcagaagctcaagcagacggacacgtatcgcgaatcgatggcgcgcgcgcgc
gaatgggtcgtcggcatgcagagtagcgacggcggctggggcgcgttcgaaccggaaaac
acgcagtactacctgaacaacatcccgttctcggatcacggcgcgctgctcgacccgccg
acttccgacgtgtcgggccgctgcctgtcgatgctgtcgcagcttggcgagagtgcgttg
accagcgagccggcccgtcgcgcgctcgactatatgctgaaggaacaggaaccggacggc
agctggtacggccgctgggggatgaactacgtgtacggcacgtggaccgcactatgctcg
ctgaacgctgccggcctgacgccggacgatccgcgcatgaagcgcggcgcgcagtggctg
ctgtcgatccagaacaaggacggcggctggggcgaggacggcgacagctacaagctcaac
taccgcggcttcgagcaggcgccgagcacggcgtcgcagacggcctgggcgctgctcggc
ctgatggcggccggcgaggtgaacaacccggccgtggcacgcggcgtcgactacctgatc
gcccggcagaacgaagaaggcctgtgggacgagacgcgcttcacggcgaccggcttcccg
cgcgtgttctacctgcgctatcacggctatcgcaagttcttcccgctgtgggcgctcgcg
cgctatcgcaacctgaagcgcgccaacgcgacgcgcgtgacggtcgggatgtaa
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