Brevibacterium flavum: C628_02555
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Entry
C628_02555 CDS
T04445
Name
(GenBank) uroporphyrin-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
bfv
Brevibacterium flavum
Pathway
bfv00860
Porphyrin metabolism
bfv01100
Metabolic pathways
bfv01110
Biosynthesis of secondary metabolites
bfv01120
Microbial metabolism in diverse environments
bfv01240
Biosynthesis of cofactors
Module
bfv_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
bfv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
C628_02555
Enzymes [BR:
bfv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
C628_02555
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
C628_02555
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ANR61499
UniProt:
A0AA86GVD8
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Position
556345..558141
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AA seq
598 aa
AA seq
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MTIAHKPEMAETTGIETNQVSETIGVESLTHGNLRPVSSFEGQHEGQTEELLPGKVIFVG
AGPGNPDLLTVRAREVLGNAVRAITDEQVLSGVRAFVATEIPVPEDKLQAAEDEYERICI
EAKENGARRKPPRPAPPTAAEITEVSEATPAQIVELVQDALSYGGDVIRLVTGNPLSSDA
TLAEISAVSEAGLEFQVVPGMSLPGTVPAFAGIALGSTYTETDVNGQDLDWDQLASAPQP
LVLQARVDDLSRIAQELKARNMSLETPVSVTVNGTTRLQRTYDTTLGLLHKLDAELSGPL
VVTLGKGVDDRSKYSWWENRALYGWRVLVPRPREQAASMSARLSSHGAIPQEVPTISVEP
PRNPAQMERAIKGIVEGRYQWVVLTSVNAVKAVWEKITEFGLDSRSFAGVRIAAVGEKTA
AEIRALGITPELLPARTRQNAQGLVDVFPEYFEELDPVGRVLLPRADIATDVLVDGLTHL
GWEVEDVVAYRTVRAAPPSADIRDMIKTGGFDAVAFTSSSTVKNLVGIAGKPHPRTIVAC
IGPMTAATAEELGLRVDVMPEIAEVPELIDALAEHVADLRAKGELPPPRKKRRRRKAS
NT seq
1797 nt
NT seq
+upstream
nt +downstream
nt
atgactatcgcccataagcccgagatggctgaaactaccgggatcgagaccaaccaggtt
tccgaaaccatcggggttgaatcgctcacgcacggaaacttacgtcctgtttcatctttt
gagggacagcatgagggacaaacggaagagttacttccaggcaaagtcatttttgttggg
gccgggcccggtaaccctgatcttcttacagttcgtgcccgtgaagttctgggcaacgcg
gttcgtgcgattactgatgaacaagtactaagtggcgttcgagcttttgtcgccactgaa
attcctgtgccggaagataagcttcaggccgcggaagatgagtacgagcggatctgcatt
gaagcgaaggagaacggtgcacgccgtaagcctcctcgtccagcaccaccaaccgctgca
gagatcacggaagtttctgaggcgactccagctcagattgttgagcttgtgcaggatgct
ctttcttatggtggagatgttattcgtcttgtcaccggcaacccattgagcagcgatgcc
acactggctgagatctctgcagtttccgaggctggcctggagttccaggtggttccaggt
atgtctttgcctggaacggttcctgcatttgcgggaatcgcgttgggctcgacctacacc
gaaactgacgttaacggtcaggatttggactgggatcagttggctagcgcacctcagcct
ttggtgctgcaggcccgcgtggatgacctttcccgtattgcacaggaactaaaggcccgc
aatatgtctttggaaactcctgtttctgtcaccgttaacggcaccacccgtttgcagcgc
acctatgacaccaccctcggtttgttgcacaagcttgatgctgaactgagcggacctttg
gttgttaccttgggcaagggcgtggatgatcgctccaagtactcatggtgggaaaaccgc
gctctgtacggttggcgtgtgctggtgcctcgccctcgggagcaagcggcatccatgtcc
gcacgtctgagcagccacggcgctatcccgcaggaagtccccacgatttcggtcgagcca
ccgcgcaacccagcgcaaatggaacgcgccatcaagggcatcgtcgaaggacgctaccag
tgggttgtcctcaccagcgtcaacgcagtgaaggcagtctgggagaaaatcaccgaattc
ggcctcgattcacgttccttcgcgggcgtccgcatcgccgcagtcggtgaaaaaaccgcc
gctgagatccgcgcgctcggcatcacgccggagcttctgcctgcacgtaccaggcaaaat
gcgcaagggcttgtcgacgtgttccccgaatatttcgaagaactcgatccagtcggccgt
gtcctcttgccgcgcgcagatatcgcaaccgacgtgcttgtcgacggcttgacccacctt
ggttgggaagtcgaagacgtggtggcttaccgcaccgtccgcgcagcaccaccaagcgct
gacatccgcgacatgattaaaactggtggattcgatgccgtggccttcacctcttcatcg
accgtgaagaacctcgttggtattgcaggtaaaccacacccacgcaccatcgtcgcgtgc
atcggacccatgactgcagcgaccgctgaagaactgggactgcgcgttgatgtcatgcca
gagatcgccgaagtaccagaactgatcgacgctcttgcggaacacgtggcggatctgcgc
gctaagggcgagctgccgccgccgaggaagaaacgcaggcgtcgaaaagcgtcttaa
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