Bos indicus (zebu cattle): 109566330 Help Entry 109566330         CDS       T04792                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism biu  Bos indicus (zebu cattle) Pathway biu00230   Purine metabolism biu01100   Metabolic pathways biu01522   Endocrine resistance biu04015   Rap1 signaling pathway biu04020   Calcium signaling pathway biu04022   cGMP-PKG signaling pathway biu04024   cAMP signaling pathway biu04062   Chemokine signaling pathway biu04072   Phospholipase D signaling pathway biu04114   Oocyte meiosis biu04211   Longevity regulating pathway biu04213   Longevity regulating pathway - multiple species biu04261   Adrenergic signaling in cardiomyocytes biu04270   Vascular smooth muscle contraction biu04371   Apelin signaling pathway biu04540   Gap junction biu04611   Platelet activation biu04713   Circadian entrainment biu04714   Thermogenesis biu04723   Retrograde endocannabinoid signaling biu04724   Glutamatergic synapse biu04725   Cholinergic synapse biu04727   GABAergic synapse biu04740   Olfactory transduction biu04750   Inflammatory mediator regulation of TRP channels biu04911   Insulin secretion biu04912   GnRH signaling pathway biu04913   Ovarian steroidogenesis biu04914   Progesterone-mediated oocyte maturation biu04915   Estrogen signaling pathway biu04916   Melanogenesis biu04918   Thyroid hormone synthesis biu04921   Oxytocin signaling pathway biu04923   Regulation of lipolysis in adipocytes biu04925   Aldosterone synthesis and secretion biu04926   Relaxin signaling pathway biu04927   Cortisol synthesis and secretion biu04928   Parathyroid hormone synthesis, secretion and action biu04934   Cushing syndrome biu04935   Growth hormone synthesis, secretion and action biu04962   Vasopressin-regulated water reabsorption biu04970   Salivary secretion biu04971   Gastric acid secretion biu04972   Pancreatic secretion biu04976   Bile secretion biu05032   Morphine addiction biu05163   Human cytomegalovirus infection biu05166   Human T-cell leukemia virus 1 infection biu05200   Pathways in cancer biu05207   Chemical carcinogenesis - receptor activation biu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:biu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     109566330 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109566330 (ADCY3)    04371 Apelin signaling pathway     109566330 (ADCY3)    04020 Calcium signaling pathway     109566330 (ADCY3)    04072 Phospholipase D signaling pathway     109566330 (ADCY3)    04024 cAMP signaling pathway     109566330 (ADCY3)    04022 cGMP-PKG signaling pathway     109566330 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     109566330 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     109566330 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109566330 (ADCY3)    04062 Chemokine signaling pathway     109566330 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     109566330 (ADCY3)    04923 Regulation of lipolysis in adipocytes     109566330 (ADCY3)    04912 GnRH signaling pathway     109566330 (ADCY3)    04913 Ovarian steroidogenesis     109566330 (ADCY3)    04915 Estrogen signaling pathway     109566330 (ADCY3)    04914 Progesterone-mediated oocyte maturation     109566330 (ADCY3)    04921 Oxytocin signaling pathway     109566330 (ADCY3)    04926 Relaxin signaling pathway     109566330 (ADCY3)    04935 Growth hormone synthesis, secretion and action     109566330 (ADCY3)    04918 Thyroid hormone synthesis     109566330 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     109566330 (ADCY3)    04916 Melanogenesis     109566330 (ADCY3)    04925 Aldosterone synthesis and secretion     109566330 (ADCY3)    04927 Cortisol synthesis and secretion     109566330 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     109566330 (ADCY3)    04270 Vascular smooth muscle contraction     109566330 (ADCY3)   09154 Digestive system    04970 Salivary secretion     109566330 (ADCY3)    04971 Gastric acid secretion     109566330 (ADCY3)    04972 Pancreatic secretion     109566330 (ADCY3)    04976 Bile secretion     109566330 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     109566330 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     109566330 (ADCY3)    04727 GABAergic synapse     109566330 (ADCY3)    04725 Cholinergic synapse     109566330 (ADCY3)    04723 Retrograde endocannabinoid signaling     109566330 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     109566330 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     109566330 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     109566330 (ADCY3)    04213 Longevity regulating pathway - multiple species     109566330 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     109566330 (ADCY3)    04714 Thermogenesis     109566330 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109566330 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     109566330 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109566330 (ADCY3)    05163 Human cytomegalovirus infection     109566330 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     109566330 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     109566330 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     109566330 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     109566330 (ADCY3) Enzymes [BR:biu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      109566330 (ADCY3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  109566330 NCBI-ProteinID:  XP_019826170 UniProt:  A0A6P5CKI9 LinkDB All DBs Position 11:76542704..76626754 Genome browser AA seq 1145 aa AA seqDB search MPRTQGFSEPEYSAXXXAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLXRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDII LFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREILANVFLYLCAIVVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCD YLEEKGIETYLIIASKPEVKKTAAQNGLNGSALLNGAPPSSKPSSPALIETKESNGSIHT SGSISEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAVVEILIDPWLMTN YVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSK YSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKDEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGASITLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggacccagggcttctccgagccygagtactccgcggnnnnnncggccgagtac tctgtcagcctgccttcggacccggaccgcggggtgggccggacccatgaaatctctgtc cggaactcggggtcgtgcctctgcttgcstcgcttcatgcggctgaccttcgtaccagag tccttggagaacctgtaccagacctacttcaagaggcagcgccacgagaccctgctggtg ctggtggtcttcgcggccctcttcgactgctatgtggtggtcatgtgcgctgtggtcttc tctggcgacaagctggcccccctggccgtggctggggtcgggctggtgttggacatcatc cttttcgtgctctgcaaaaaggggctgctccccaaccgggtcactcggagagtggtgccc tacctgctgtggctgctgatatcagcccaggtcttctcctacctgggcctgaacttctcc cgtgcccaygcggccagcgacacggtgggctggcaggccttcttcgtcttctccttcttc atcacgctgccgctcagcctcagccccattgtcatcatctccgtggtctcctgcgtcgtg cacacactcgtcttgggggtcactgtggcccagcarcagcaggatgggctgaagggagtg cagttgctgagggagattctggccaacgtcttcctctacctgtgcgccatcgtcgtgggc atcatgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tctctggaggtgaagatgaacctggaggagcagagtcagcagcaggagaaccttatgctc tccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaagaaggatgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc ctctttgctgatatcgtgggcttcacccagctgtcctcagcctgcagcgcccaggagctt gtgaagctgctcaatgagctctttgcccgcttcgacaagctggcggctaaataccaccag ctgcggattaagatcctgggcgactgttactactgcatctgtgggctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggagaagacgaagaccggggtggacatgcgcgtgggggtgcacacgggcaccgtg ctggggggcgtcctyggccagaaacgctggcagtacgacgtgtggtccaccgacgtcacc gtggccaacaagatggaggctggcggcatccctgggcgtgtgcacatctcccagagcacc atggactgcctgaaaggagagttcgacgtggagccgggcgaggggggcagtcgctgtgat tacctggaagagaagggcattgagacctacctcatcatcgcttccaagccagaggtgaag aagacagctgcccaaaatggcctcaacggctcggccctgctgaacggagcgccgccktcc tcaaagcccagctcccctgccctcattgagaccaaggagtccaacgggagcattcacacc agcggctctatatctgaggagccygaggagcaagatgcccaggccgacaacccctcgttc cccaaccctcgccggaggctgcgccttcaggacctggctgatcgcgtggtggacgcctcc gaggacgagcatgagctcaaccagctactcaacgaggcgctgctagagcgggagtctgcc cargtagtgaagaagagaaacaccttcctcctgtccatgcggttcatggaccccgagatg gaaacccgctactcggtggagaaggagaagcaragcggggctgccttcagctgctcctgc gttgtcctactctgcacggccgtggtggagatcctcattgacccctggctcatgacgaac tatgtgacctttgtggttggggaggctctgctcctgatcctgacaatctgctcgctggct gccatctttccgcgggcctttcctaagaagctcgtggccttctctacttggattgaccgg acgcgctgggccaggaacacctgggccatgctggccatcttcattcttgtcatggcaaac gtggtggacatgctcagctgtctccagtactacacaggacccaccaacggcaccgcagag atgcaggtggaggatggctgcgtggagaaccccaagtattacaactacgtggccgtgctg tccctcatcgccaccatcatgctggtgcaggtcagccacatggtcaagctcacactcatg ctgctcatcgcgggggccgtggctgtcatcaacatctacgcctggtgccccatctttgac gactacgaccgcaaacgcttccagcaacacgactttccgatggtggccttagagaagatg caggtgttttccagctcggggctcaatggcactgacaggctgcccctggtgccgtctaag tactcgatgacagtgatgatctttgtcatgatgctgagcttttactacttctcccgccac gtggaaaagctggcacggacactgttcttgtggaagattgaggtccacgaccagaaggaa cgtgtctatgagatgcgacgctggaatgaagccttggtcaccaacatgctacctgaacac gtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcttat gatgagattggagttatgtttgcctccctgcccaattttgctgacttctacacagaggag agcatcaataacggtggcattgagtgtctacgcttcctcaatgagatcatctcagatttt gactctcttctggacaatcccaagttccgggtcatcaccaagatcaagaccattggtagc acctacatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggacgagaagtcagacaaggagcgctggcagcacctggcagatctggccgatttt gcgctggccatgaaggacacgctcaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcattggaatgaacaaaggaggggtcctggctggggtcattggagcccggaaacca cactatgacatctggggcaacacagtcaacgtagccagcaggatggagtccacaggggtc atgggcaacatccaggtggtggaagaaacccaagtcatccttcgagaatacggcttccgc ttcgtgaggagagggcccatctttgtgaaagggaagggggaactgctaacctttttcttg aagggccgagacaagctggccacattccctaacggcgcctcaatcacactgcctcaccag gtggtagacaactcctga

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