Balaenoptera musculus (blue whale): 118880961
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Entry
118880961 CDS
T09887
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus04120
Ubiquitin mediated proteolysis
bmus04144
Endocytosis
bmus04330
Notch signaling pathway
bmus04668
TNF signaling pathway
bmus04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
118880961 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
118880961 (ITCH)
04668 TNF signaling pathway
118880961 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
118880961 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
118880961 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
bmus04131
]
118880961 (ITCH)
04121 Ubiquitin system [BR:
bmus04121
]
118880961 (ITCH)
Enzymes [BR:
bmus01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
118880961 (ITCH)
Membrane trafficking [BR:
bmus04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
118880961 (ITCH)
Ubiquitin system [BR:
bmus04121
]
Ubiquitin ligases (E3)
HECT type E3
118880961 (ITCH)
BRITE hierarchy
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
118880961
NCBI-ProteinID:
XP_036681103
EnsemblRapid:
ENSBMSG00010014131
LinkDB
All DBs
Position
15:complement(24716270..24839088)
Genome browser
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVANGETTCSESASQNDDGSRPKDETRVNTNGS
DHPEDAGSGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactc
cagataactgtcatttcagcgaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaacctcttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccaacagagacaataggagatttgtcagtttgtcttgat
gggctgcagctagagtctgaagttgttgctaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagagtgaacacaaatggatca
gaccaccctgaggatgcagggtctggtgaaaataggagggtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggctcaccatctgccacttctgaaagtgat
ggctctagtacaggctctctgccaccaacgaatacaaattcaaatacatctgaaggagca
acttctggattaataattcctcttactatatctggaggttcaggccctaggccattaaat
cctgtacctcaagctcccctcccacccggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacgacgtggcagaggccaacattggaatccgtccggaactatgaacaatggcag
ctccaacgtagtcagcttcaaggagctatgcagcaatttaaccagaggttcatttatggg
aatcaagacttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgcca
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaatact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgaggttcacagtagatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataattactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgctatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtatttttccgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgcggtgttgaagaacagacacaagccttctttgagggcttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggaattagaggttctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgagacttttgcagtttgtaactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatgggccacagaaattctgcattgaaaaagttgggaaa
gaaaattggttgcctagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctattatttgctattgaagaaacagaaggatttgga
caagagtga
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