Balaenoptera musculus (blue whale): 118893214
Help
Entry
118893214 CDS
T09887
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00310
Lysine degradation
bmus01100
Metabolic pathways
bmus05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
118893214 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
118893214 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
bmus03036
]
118893214 (DOT1L)
Enzymes [BR:
bmus01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
118893214 (DOT1L)
Chromosome and associated proteins [BR:
bmus03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
118893214 (DOT1L)
HMT complexes
Dot1-containing complex
118893214 (DOT1L)
BRITE hierarchy
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
118893214
NCBI-ProteinID:
XP_036704412
EnsemblRapid:
ENSBMSG00010009150
LinkDB
All DBs
Position
3:complement(169835529..169893817)
Genome browser
AA seq
1718 aa
AA seq
DB search
MGEKLELRLESSVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAMPADTPMDSGAEEEKAGATAVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKTQSALDLLHAQTVSRAASPSPQGAPYQLPPSTQRRPPEQLLLAPAPPALHRL
LESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLVGAVQQLFGHCQAQKEEIKRLF
QQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNRELRSQSLRLLQARCEEL
KLDWPTLSLEGLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDD
ALSLHLRGKGGLGREQEAEPGRPHLELDCARFSLPHLSNMSPELSMNGHAAGYELCGALS
RPSPKQNTPQYLASPLDQEVVPCTPNHSGRPRLEKLSGLALPDYTRLSPAKLVLRRHLSQ
DHTANSRATASELHPRAEHAKENGLPYQSPGIANGIKLSPQDPRPSSPAALQMTGEKGSE
KGWKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRSTPSPVPQA
REPSSTLEKQMGAGAHGSGGSAAGSRSLALAPAGFAYAGSVAISGALAGSPAPLVSGAEP
PALDESSSSGSLFATVGSRSSTPQHPSLLAQPRNCGSASPAPQLCASPRLGAQGPLPDAS
KGDLPSEAGFSDPESEAKRRIVFTISASSSSAKQSPSSKHSPLSSGARGDGGQSHGQDSR
KRGRRKRAAAGTPGLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAIS
SPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSARIERKI
ATISLESKSPPKTLENGGGLAGRKVPASEPVNSSKWKSTFSPISDLGLAKAADSPLQAAS
ALSHSSLFAFRPGLEEPGAADAKLAAHPRKSFPGALPGAGGLSPSSHPASGFALGGGLAA
DLSLHSFSDGASLSHKAPEAAGLGAPLSFPGPRGKEGGAAEPGPFVNKRQLDGLAPKGEV
GPPVCGPADKASATHGKAGKGRDREPDVKNGHNLFMAAAAAAAAAAAPPGGLLSGPGLAP
AASSAGGTAPSAQTHRPFLGAFAPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVS
TAATRLTNSHAMGSFSSGVAGGAVGGAFNHAVPPASAHPFGASFGSGAACRSATLSLTPL
QAVASTPASSFQAPSPAEPRPPPPPPHLGRPPLGQPALHAPPPPNAALPPPPALLPANSE
PVLLQNLASLPANQAFLPASSAASVPPANASLSIKLASLPHKVSRPSFTVHHPPLPGLAL
AQAAPVIPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq
5157 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagttggagctgaggctggagtcgtccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccggtgggtctgtgaagaaatcccagatctcaagctcgctatggagaattatgtttta
atcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacacg
cggccgtccacggggctcctgcgccacatcctgcagcaggtctacaaccactcggtgacc
gaccccgagaaactcaacaactacgagcccttctccccggaggtgtacggggagacctcc
ttcgacctggtcgcccagatgatcgacgagatcaagatgaccgaggacgacctgtttgtg
gacctgggtagcggagtgggccaggttgtgctgcaggtcgccgcggctaccaactgcaaa
catcactatggtgtcgagaaagctgacatcccggccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggagaga
ggagatttcctctcggaggagtggagagagcggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggttcgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctgtcgccgctaaaa
ggctcggtgtcgtggacggggaagccggtgtcttactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgggagaacaagagcaacacgaccacccccaccaaggtgccc
gagagcaaggcggccatgcccgccgacacccccatggactctggtgctgaggaagagaaa
gccggggcgaccgctgtcaagaagccgtctccctccaaggcccggaagaagaagctgaac
aagaagggccggaagatggctggccggaagcgcggacgtcccaagaagatgagcaccgcc
aaccccgagcgcaagcccaagaagacccagagcgcactggacctgctgcacgcccagacc
gtgtcgcgggcggcgtcaccctcgccgcagggcgccccctaccagctacctcccagcacg
cagcggcgcccccctgagcagctgctgctggcgcccgccccgcccgccctgcacaggctg
ctagaatccttcaagattcagtacctacagttcctggcatacacaaagacccctcagtac
aaggccaacctgcagcagctgctggaccaggagaaggagaagaacgcccggttggtgggc
gccgtgcagcagctgttcggccactgccaagctcagaaggaggagatcaagaggcttttc
cagcagaaactggatgagctgggagtgaaggcgctgacctacaacgacctgatccaagcg
cagaaggagatctcggctcacaaccagcagctgagggagcagacggagcagctggaaaag
ggcaaccgggagctgaggagccagagcctgcggctgctccaggcacggtgcgaggagctg
aagctggactggcccacgctgtccctggagggcctgctgaaggagaagcaggccctgaag
agccagatctcggagaagcagaggcactgcctggagctgcagatcagcatcgtggagctg
gagaagagccagcggcagcaggagctcctgcagctcaagtcctgcgtgccgcccgacgac
gccctgtccctgcacctgcgcgggaagggtggcctgggccgagagcaggaggctgagccc
ggccggccacacctggagctggactgcgccaggttctccctgccccacttgagcaacatg
agcccagagctgtccatgaacggccacgcggccggctacgagctctgcggcgcgctgagc
cggccctcgcccaagcagaacaccccccagtacctggcctcccccctggaccaggaggtc
gtgccctgcaccccgaaccacagtggccggccgaggctcgagaagttgtccggcctggcc
ctgcccgactacaccaggctctcccctgccaagctggtgctgcggcgccacctgagccag
gaccacacagccaacagcagggcgaccgccagcgagctgcacccacgagctgagcatgcc
aaggagaatggcctcccgtaccagagccccggcatcgccaatggcatcaaactgagcccg
caggaccctcggccctcgtcccctgcggccttgcagatgacgggagagaagggcagtgag
aagggttggaaggagcgcacctacgccagcagtggggaggccatcaccagcctgcccgtc
agcatcccgctcagcaccgtgcagcccagcaagctgccagtcagcatccctctggccagc
gtggtgctgcccagccgcgccgagaaggtgagaagcacccccagccccgtgccgcaggcc
cgagagccctcgtccacgctggagaagcagatgggtgctggcgcccacggctccgggggc
agcgctgctgggagcagaagcctcgccctggcccccgcgggcttcgcctacgccggctcg
gtggccatcagcggggccctggcaggcagcccggcaccactcgtctctggagccgagccc
cccgccctggatgagtcctccagctccggaagcctcttcgccactgtggggtcccgcagc
tccacccctcagcacccctccctgctggcgcagccccgcaactgcggctcggcctcgccc
gccccccagctctgcgccagtccccggctcggcgcccagggcccgctccccgacgccagc
aaaggagacctgccctctgaggccggcttctcggatcccgagagtgaagccaagagaagg
atcgtcttcaccatctcggccagctccagcagcgccaagcagtcgccttccagcaagcac
agccctctgtcctcgggcgcccgcggtgacggcggccagagccacgggcaggacagccgc
aagaggggcaggaggaagcgggccgcggcagggacccccggcctcagctcgggcgtgtcc
cccaagcgccgggccctgccgtccgtcgccggcctcttcacccagtcttcagggtccccc
ctgaacctcaactccatggtcagcaacatcaaccagcccttggaaatcacggccatctca
tcccctgagagctccctgaagagctcgcctgtcccttaccaggacaacgaccagccgccc
gtgctcaagaaggagaagcccctgagccagaccaacggggcccactattccccgctgacc
tcggatgaggagcagggctctgaggacgagcctggcagtgccagaattgaaagaaaaatt
gcaacaatctccttagaaagcaaatctcctccgaaaaccttggaaaatggtggcggcctg
gcgggaaggaaggtgccggccagtgagccggtcaacagcagcaagtggaagtccaccttc
tcgcccatctccgacctcggcctggccaaggcagccgacagcccgctgcaggccgcctcc
gctctgagccacagctccctgttcgctttccggcccggcctggaggaacctggcgcggct
gacgccaagctggccgcccaccccaggaagagcttcccaggcgcgctgccgggagcgggc
gggctgagccccagcagccatcccgccagcggcttcgccctgggcgggggcctggcagcc
gacctcagtttacacagcttcagcgatggtgcttctctctcccacaaggcccccgaggcg
gccggcctgggcgcccccctgagctttcccggcccgcggggcaaggagggtggcgccgca
gagcccggccccttcgtgaacaagaggcagctggacggactggccccaaagggcgaggtt
ggcccgcctgtgtgcgggcccgcggacaaggcctcagcgacgcacggcaaggcgggcaag
ggccgtgaccgcgagcccgacgtcaagaacggccacaacctcttcatggccgccgccgcc
gccgccgccgccgccgccgcgccccccgggggcctcctcagcggcccgggccttgccccg
gcggcgtcctcggcagggggcacggccccgtccgcccagacccaccgccccttcctgggc
gccttcgcccccggcccgcagttcgcgctgggccccatgtccctgcaggccaacctgggc
ccgtccgtgctgcagtccctgttcagctccgtgcccgccgctggcctggtgcacgtctca
accgctgccaccagactgaccaactcgcacgccatgggcagcttctcctccggggtggcc
ggcggtgcagtcggaggtgcctttaaccacgcggtgcctcccgcctccgctcatccgttt
ggagccagtttcggcagtggggctgcatgtcgcagcgccacgctgagcctaaccccgctg
caggcggtggccagcaccccggcctcttcctttcaggccccgtcccctgcggagccgagg
ccgcccccgccccctccgcacctgggccggccccctctggggcagcccgccctccacgcc
cccccccctcctaacgccgccttgcctccgccccccgcgctgctcccggctaactctgag
cccgtgctcctgcagaacctcgcgtccctcccagctaaccaagctttcttacctgcctcc
tctgctgcctctgtgccgcctgctaacgcctctctgtccatcaagctcgcctcacttccg
cacaaggtgtcccgcccctccttcacggtgcaccacccgcccctgcccgggctggccctg
gcccaggccgcgcccgtgatcccgcaggccagctccacggggccgcccgccgtgtgggtt
tcccttggcatgccacctccgtatgccgcgcgccttgcgggggttaagccgcgataa
DBGET
integrated database retrieval system
