Bos mutus (wild yak): 102280735
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Entry
102280735 CDS
T02919
Symbol
DOT1L
Name
(RefSeq) DOT1 like histone lysine methyltransferase
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom00310
Lysine degradation
bom01100
Metabolic pathways
bom05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
102280735 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
102280735 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
bom03036
]
102280735 (DOT1L)
Enzymes [BR:
bom01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
102280735 (DOT1L)
Chromosome and associated proteins [BR:
bom03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
102280735 (DOT1L)
HMT complexes
Dot1-containing complex
102280735 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
102280735
NCBI-ProteinID:
XP_014336293
LinkDB
All DBs
Position
Un
AA seq
1665 aa
AA seq
DB search
MAVLDLFTVDYVFPRLPGQPGTHSLCLRISLLCTFPVPWWGIDSDPCWGGTVLEHSELQC
SRPVEREKRPERRGCESFRVIQVGPLQALQEEGSWTCPGCLGAQRWSVVHSWAQSGHMAL
CFLHISLNSGRVSVICDRSRGLQRVRDSEPGLRLPGYKSAQESLVEGGLEDKHHDAAHEI
IETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMK
LNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDD
LFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYT
LERGDFLSEEWRERIANTSVVFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNF
RINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREE
QEAARRRQQRENKSNTTTPTKVPESKAAVQADTPVDSGAEEEKAGTATVKKPSPSKARKK
KLNKKGRKMVGRKRGRPKKMSATNPERKPKKTQSSLDLLHAQTASRAASPLPQDAHRPPH
SPFYQLPPSVQRPTPEQLLLAPTPPALHRLLESFRIQYLQFLAYTKTPQYKASLQQLLDQ
EKEKNARLLGAAQQLFGHCQAQKEEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQ
LREQTEQLEKGNWELRSQSLRLLKARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHC
LELQISIVELEKSQRQQELLQLKSCVPPDEALALQLRGKPEAEPSRLHLELDCARFSLPP
FSSLSPELSMNGHAAGYELCSALGRPSPKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKL
SSLALPDYTRLSPAKLVLRRHLSQDHAASGKAAASELHPRAEHAKENGLPYQSPGITNGI
KLSPQDPRPSSPMALQMGEKGPEKGVKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIP
LASVVLPSRAEKARSTPSPGPPARESSSTLEKQVAANTHGAGGNAAGSKSLALAPTGFAY
TGSVAISGALAGSPAPLAPGAEPPALDESSSSGSLFATVGSRSSTPQHPPLLTQPRTCGS
ASPAPQLCSSPRLGALGPLPDSGKGDLPCEASFSDPESEAKRRIVFTISAGASSAKQSPS
SKHSPLPSGARGDGGQGHGPDGRKRGRRKRASAGTPSLSSSVSPKRRALPSVAGLFTQSS
GSPLNLNSMVSNINQPLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYS
PLTSDEEPGSEDEPGSARIERKIATISLESKSPPKTLENGGSLAGRKAPLASEPVNSSKW
KSTFSPISDLGLAKAADSPLQAASALSHNSLFAFRPGLEEPSAADAKLATHSRKSFPGTL
PGAGGLSPSSLPASGFALGGGLAADLSLHSFSDGASLSHKAPEAAGLGAPLSFPGPRGKE
GGAAESGPFVNKRQLDGLGPKGEGGLPTCGPPDKASTAHSKAGKGREREPDVKNGHNLFM
AAATAPPAGLLSGPGLAPAASSAGGAAPSVQTHRPFLGAFAPGPQFALGPMSLQANLGPS
VLQSLFSSVPAAGLVHVSTAATRLTNSHAMGSFSSGVAGGAVGGN
NT seq
4998 nt
NT seq
+upstream
nt +downstream
nt
atggcggtgctggacctgttcacagtggattatgttttccctcgtctcccgggacaacca
ggaacccactctctgtgtctgcggatcagcctgctctgcacatttcccgtaccctggtgg
ggcattgacagtgacccctgctggggtgggacagtgctggagcactcagagctgcagtgc
tcaagacctgtggagcgtgagaagcggccagagcggagaggttgtgagagcttccgagtc
attcaggtggggcccctgcaggccctgcaggaggaggggtcctggacttgtcctggctgc
ctgggggcccagagatggagcgtggtccacagctgggcacagtccggccacatggcgctg
tgcttcctgcatatcagcctaaactcaggccgtgtatcggttatctgtgacagaagccga
ggcctgcagagggtcagggactcagagccaggcctgcggctgcccggctacaagagtgcc
caggagagccttgtggaaggcgggttggaagacaaacaccacgatgctgctcatgaaatc
atcgagaccatcagatgggtctgtgaagaaatcccggatctcaagcttgctatggagaat
tacgttttaattgactacgataccaaaagctttgagagtatgcagaggctctgtgacaag
tacaaccgggccatcgacagcatccaccagctgtggaagggcaccacacagcccatgaag
ctgaacacacggccatccacggggctcctgcggcacatcctgcagcaggtctacaaccac
tcagtgaccgaccctgagaagctcaacaactacgagcccttctccccagaggtgtatggg
gagacctccttcgacctggtcgcccagatgatcgatgagatcaagatgaccgaagatgac
ctgttcgtggacctgggcagtggagtgggccaggttgtgctgcaggttgccgcggccacc
aactgcaaacatcactacggtgtagagaaagctgacatcccagccaagtacgcggagacc
atggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacaca
ctggagaggggggacttcctctcggaggagtggagagaacggattgctaacacaagtgtt
gtatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaaggagcggttt
gcaaacatgaaggaaggtggcagaatcgtgtcctcgaagccctttgcacctctgaacttc
agaataaacagtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctgtcg
ccgctaaaaggctcggtgtcatggacggggaagccggtctcctactacctgcacaccatc
gaccgcaccatacttgaaaactatttttctagtctaaaaaatccaaaactcagggaggaa
caagaggcagctcggcgccggcagcagcgggagaacaagagcaacacaaccacgcccacc
aaggtgcccgagagcaaggcagctgtgcaggcggacacccccgtggactctggtgctgag
gaggagaaagccgggacggccactgtcaagaagccatctccctccaaggcccggaagaag
aagctgaacaagaagggccggaagatggtgggtcggaagcgtgggcgccccaagaagatg
agtgccaccaaccccgagcgcaagcccaagaagacccagagctcactggacctgctgcac
gcccagactgcgtcacgagcggcctcccccttgccgcaggacgcgcacaggccacctcac
agcccattctaccagctacctcccagcgtgcagcggcctacccccgagcagctgctgctg
gcacccaccccgcccgcactgcacaggctgctagagtccttcaggattcagtacctacag
ttcctggcatacacgaagacccctcagtacaaggccagcctgcagcagctcctggaccag
gagaaggagaagaatgcccggttgctaggcgcagcgcagcagctatttggccactgccaa
gctcagaaggaggagatcaagaggctcttccagcagaaactggacgagctgggagtgaag
gcgctgacctacaacgacctgatccaagcgcagaaggagatctcggctcacaaccagcag
ttgagggagcagacggagcagctggagaagggcaactgggagctgaggagccagagcctg
aggctgctcaaggcacgatgcgaggagctgaagctggactggtccacgctgtcgctggag
aatctgctgaaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgc
ctggagctgcagatcagcatcgtggagctggagaagagccagcggcagcaggagttgctg
cagctcaagtcctgcgtgccgcctgatgaggcactggctctgcagcttcgtgggaagcca
gaggctgagcctagccggctgcacttggagctggactgcgcccgcttctccctgccgccc
ttcagcagcttgagccccgagctctctatgaatggccacgcagccggctatgagctctgc
agcgcactgggtcggccctcgcccaagcagaacaccccccagtacctggcctccccgcta
gaccaggaggtcgtgccctgcacccctagccacagcggccggccacggctagagaagctg
tccagcctggccctgcctgactacaccaggctatcccctgccaagctggtgctgcggcgc
cacctgagccaggaccacgcggccagtggcaaggcagctgccagtgagctgcacccacga
gccgagcatgccaaggagaatgggctcccttaccagagccctggcatcactaatggcatc
aagctgagcccacaagacccccgaccttcatcccccatggctttacagatgggagagaag
ggccccgagaagggtgtgaaggagcgtgcctacgccagcagtggggaggccatcaccagc
ctgcccgtcagcatcccgctgagcaccgtgcagcccagcaagctgcccgtcagcatcccc
ctggccagcgtggtgctgcccagccgcgccgagaaggcgagaagcacacccagccctggg
ccaccggcccgagagtcctcatccacgctggagaagcaggtggctgctaacacccatggt
gccgggggcaacgctgctgggagcaagagcctcgccctggctcccacaggctttgcatac
accggctcggtggccatcagtggggccctggccggcagcccggcacccctcgcccctgga
gccgagcccccagccctggacgagtcctccagctctggaagcctctttgccaccgtgggg
tcccgcagctccaccccgcagcacccacccctgctgacgcagccacgcacctgtggctcg
gcctcgccggccccccagctctgctccagcccccggcttggcgctctgggcccactcccc
gactctggcaaaggggacctgccctgcgaggccagcttctcagaccctgagagcgaagcc
aaaaggagaatcgtcttcaccatctcggcgggcgccagcagcgccaagcagtcaccttcc
agcaaacacagccctctgccgtcgggtgcccgcggggacggtggccagggccatgggcca
gacggccgcaagcggggccggaggaagcgggcatcggcggggacccccagcctgagctcg
agtgtgtcccccaagcgccgggccttgccatctgtcgctgggcttttcacgcagtcttca
gggtcccccctgaacctcaactccatggtcagcaacatcaaccagcccctggagatcaca
gcaatctcgtcccctgagagctctctaaagagctcacccgtcccctaccaggacaacgac
caaccacccgtgctcaagaaggagaagcccctgagccagaccaatggtgcccactactcc
ccactgacttcggacgaggagccaggctctgaggatgagcccggcagtgccagaattgag
agaaaaattgcaacgatctccttagaaagcaagtctccgccaaaaaccttggaaaatggt
ggcagcctagcaggaaggaaggcgccgctggccagcgagccggtcaacagcagcaagtgg
aagtccaccttctcacccatctccgacctgggcctggccaaggcggccgacagcccgctg
caggctgcctctgctctgagccacaactctctgttcgctttccggcctggcctggaggag
cccagtgcggccgatgccaagctggccacccactccaggaagagcttcccgggcaccctg
ccaggggcgggcgggctgagccccagtagccttcctgccagcggcttcgccctgggcggg
ggcctagcagctgacctcagtttacacagcttcagtgatggtgcttctctctcccacaag
gcccccgaggcagctggcctgggtgcccccctgagcttccccggcccacggggcaaagag
ggtggcgctgcagagtctggccccttcgtgaacaagcggcagctggacggactgggccca
aaaggcgaggggggccttcccacatgcggacccccggacaaggcctccacagcgcatagc
aaggcaggcaagggccgcgagcgcgagcctgacgtcaagaacggccacaacctgttcatg
gccgctgccactgcgccccctgcaggcctcctcagcggcccaggtcttgccccagcggca
tcctcggcaggtggcgcagccccgtccgtgcagacccaccgccccttcctgggcgccttc
gcccccgggccacagttcgcactgggccccatgtcgctacaggccaacctgggcccatct
gtgctgcagtccctgttcagttccgtgcccgccgccggcctggttcacgtctcgaccgcc
gccaccagattgaccaactcgcacgccatgggcagcttctcctctggggtggccggcggc
gcagttggaggtaactag
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integrated database retrieval system
