Butyrate-producing bacterium SS3/4: CK3_03410
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Entry
CK3_03410 CDS
T02611
Name
(GenBank) 2-isopropylmalate synthase, yeast type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
bprs
Butyrate-producing bacterium SS3/4
Pathway
bprs00290
Valine, leucine and isoleucine biosynthesis
bprs00620
Pyruvate metabolism
bprs01100
Metabolic pathways
bprs01110
Biosynthesis of secondary metabolites
bprs01210
2-Oxocarboxylic acid metabolism
bprs01230
Biosynthesis of amino acids
Module
bprs_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
bprs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CK3_03410
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CK3_03410
Enzymes [BR:
bprs01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CK3_03410
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CBL40189
UniProt:
D7GQW4
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All DBs
Position
352600..354273
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AA seq
557 aa
AA seq
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MMNYKRYQRVPVMNYPEREWPNKEIEKAPIWCSVDLRDGNQALVEPMVVEEKIEMFNMLV
QMGFKEIEIGFPAASQIEFDFLRQLVERRLIPDDVTVQVLTQCRDHLLKRTFESIQGIPK
AVVHIYNSTSTLQRDVVFHMDREEIKQIAIDGVDMVKKYMKDYDGKVILEYSPESFTGTE
MDYALDICNAVQRAWGPTPDNKMIINLPSTVEMTTPNVFADQIEWMSKHLENRESIVLSV
HPHNDRGTGVAAAELAMLAGADRVEGTLFGNGERTGNVDILTIAYNMFSQGIDPELEIGD
IKKIAEVYERCTKMHIDPRHPYAGKLVFTAFSGSHQDAINKGMHALMERKSEIWQVPYLP
IDPSDIGREYEPVVRINSQSGKGGVAFVMDSFFGFKLPRGMHKEFADVIQKIAEKQGEVA
PDQIMEEFRIEYLDRKEPYHFRKCKITDFESGDQFTTVAVVTYSDHGETKQFEGVGNGPI
DAVKRGLEEELGISIKVLDYSEHALTSGSGAQAASYIHLMDQKTGKVTYGVGISSNITRA
SLRGIFSAVNRLFGDAE
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atgatgaattataagagatatcagagagtaccagtcatgaattacccggagagggagtgg
ccgaataaagagatcgagaaggcgccgatctggtgcagcgtggatctgcgcgacggcaac
caggcccttgtagagccgatggttgttgaagagaagatcgaaatgttcaatatgctggtg
cagatgggcttcaaggagatcgagatcggtttcccggccgcctcccagatcgaatttgac
tttttaaggcagcttgttgagcgcaggctgatcccggatgatgtgacggtccaggtcctg
acccagtgtcgtgaccacctgttaaagagaaccttcgagtccatccagggaatcccgaag
gcagttgtgcatatttacaattctacatccaccttacagcgtgacgttgtattccatatg
gaccgcgaggagatcaagcagatcgcaatcgacggtgtcgatatggtaaagaagtacatg
aaagattatgacggaaaagtgatcctggagtattccccggagagctttaccggaacagag
atggactatgcgcttgatatctgcaacgcggtccagagagcatggggaccgacaccggac
aataagatgatcatcaaccttccgtccactgtcgagatgacgacaccgaacgtgtttgcg
gaccagatcgagtggatgagcaaacatctggagaaccgcgagagcatcgttttaagtgtt
catccgcataatgaccgcggaacaggcgttgctgctgcagaacttgcaatgcttgcaggc
gctgaccgcgttgaaggaaccctgttcggaaacggtgagcgtaccggaaacgtggatatc
ctgaccatcgcctacaatatgttctctcagggaatcgacccagagcttgaaatcggcgat
atcaagaagatcgcggaagtttacgagcgctgcacaaagatgcatatcgatccgcgtcat
ccgtacgctggaaagctggtatttactgcattctccggttcccatcaggatgctatcaac
aagggaatgcatgcgcttatggaaagaaagagcgagatctggcaggttccgtatctgccg
atcgatccgtccgatatcggaagagagtacgagccggtggtccgtatcaacagccagtcc
ggaaagggcggtgttgctttcgttatggacagcttctttggattcaagcttccgcgcggc
atgcacaaggagttcgcggatgtgatccagaagatcgcagagaagcagggtgaggttgcg
ccggatcagatcatggaagagttccgcatcgagtatctcgaccgcaaggaaccgtaccac
ttccgcaagtgcaagatcacagatttcgagtccggagaccagttcacaaccgttgctgtt
gttacctactctgaccacggcgagacaaaacagtttgaaggtgtcggaaacggtccgatc
gatgctgtgaaacgcggactggaggaggagcttggtatctcgatcaaggttctcgattac
agcgagcatgcgctgacatccggttccggggcacaggcggcttcctatatccacctgatg
gatcagaagaccggcaaggtgacatacggtgtcggcatcagctccaacatcacgagagca
tccttaagaggtatcttcagtgcagttaaccgtctgtttggagatgcagagtaa
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