KEGG   PATHWAY: bpsd00230
Entry
bpsd00230                   Pathway                                
Name
Purine metabolism - Burkholderia pseudomallei MSHR520
Class
Metabolism; Nucleotide metabolism
Pathway map
bpsd00230  Purine metabolism
bpsd00230

Module
bpsd_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bpsd00230]
bpsd_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bpsd00230]
bpsd_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bpsd00230]
bpsd_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bpsd00230]
bpsd_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bpsd00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia pseudomallei MSHR520 [GN:bpsd]
Gene
BBX_2742  NUDIX domain protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BBX_1179  phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III family protein [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BBX_3405  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BBX_4211  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BBX_2806  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BBX_3062  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BBX_2863  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BBX_1896  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BBX_1026  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BBX_3173  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
BBX_3174  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BBX_3175  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BBX_909  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BBX_944  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BBX_3385  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BBX_1983  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BBX_2016  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BBX_839  phosphoribosyl transferase domain protein [KO:K00760] [EC:2.4.2.8]
BBX_1819  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BBX_1991  nucleoside diphosphate kinase family protein [KO:K00940] [EC:2.7.4.6]
BBX_1265  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BBX_1118  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BBX_337  peptidase C26 family protein [KO:K01951] [EC:6.3.5.2]
BBX_1821  guaA; GMP synthase (glutamine-hydrolyzing), N-terminal domain protein [KO:K01951] [EC:6.3.5.2]
BBX_1295  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BBX_1268  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BBX_4925  ribonucleotide reductase, barrel domain protein [KO:K00525] [EC:1.17.4.1]
BBX_5543  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BBX_844  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
BBX_845  ribonucleotide reductase, small chain family protein [KO:K00526] [EC:1.17.4.1]
BBX_1535  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
BBX_623  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
BBX_1270  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BBX_2589  ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BBX_2420  RelA/SpoT family protein [KO:K00951] [EC:2.7.6.5]
BBX_3247  response regulator [KO:K01768] [EC:4.6.1.1]
BBX_2005  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BBX_849  pfkB carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
BBX_4341  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BBX_1297  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BBX_3530  cpdB; 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BBX_3098  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BBX_2664  calcineurin-like phosphoesterase family protein [KO:K03651] [EC:3.1.4.53]
BBX_1158  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
BBX_1542  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BBX_4498  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BBX_2148  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BBX_1712  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BBX_3024  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
BBX_1728  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BBX_3025  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BBX_1837  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BBX_1833  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
BBX_1831  asp/Glu/Hydantoin racemase family protein [KO:K16841] [EC:5.1.99.3]
BBX_1832  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
BBX_892  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BBX_1834  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BBX_893  ureidoglycolate hydrolase family protein [KO:K01483] [EC:4.3.2.3]
BBX_1835  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BBX_5859  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
BBX_4757  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
BBX_1186  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BBX_1187  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BBX_1188  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BBX_2204  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bpsd00030  Pentose phosphate pathway
bpsd00220  Arginine biosynthesis
bpsd00250  Alanine, aspartate and glutamate metabolism
bpsd00260  Glycine, serine and threonine metabolism
bpsd00340  Histidine metabolism
bpsd00630  Glyoxylate and dicarboxylate metabolism
bpsd00730  Thiamine metabolism
bpsd00740  Riboflavin metabolism
bpsd00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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