Brooklawnia propionicigenes: brsh051_08290
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Entry
brsh051_08290 CDS
T09125
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
broo
Brooklawnia propionicigenes
Pathway
broo00860
Porphyrin metabolism
broo01100
Metabolic pathways
broo01110
Biosynthesis of secondary metabolites
broo01120
Microbial metabolism in diverse environments
broo01240
Biosynthesis of cofactors
Module
broo_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
broo_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
broo00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
brsh051_08290
Enzymes [BR:
broo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
brsh051_08290
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
brsh051_08290
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Ortholog
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BEH01548
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Position
complement(918015..919622)
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AA seq
535 aa
AA seq
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MSEQRSTLALADCDPAVLTASRHPARVIPGYVIFVGVGLGGPLRLTLAGLKAIEEADVIV
LNPGVDEGLLDEPEITTPDRAVTVVADDHPDLDKITTLVQSGLSVVWLLAGDPLMDAEAA
SYTSELRANGCRIDMVPGLSRLSLAITSTGITPGPGFRLWSGSAAMSGDGESFVALLPDQ
QADDIIAHAEQIGLPADTRALVVSDYATSAQKTTPTVLGELADVLNAVQDRPSAVIIGPA
AVRDPSLNWFESKPLFGWHVLVPRTKGLSGAMERRLEHHGAVPVQIPTISVEPPRNPQPM
ERAIQGLVDGRYQWIIFNSAQAVRAVTERLVGLGLDSRAFSGLRIAAVGADTVTALRGWG
ITPDLVPEGEARSEALASEFPIFDDLLDPINRIFIPRADVSVDSLVQSMNELGWEVDDVV
AYRTVRAAPPAAEIRDAIKAGRFDAVVFSSASTVRNMVGIAGKPHVDTIIAAIGPATVAA
CEEANLRVDVVASQPNQADLVDALAAFAVKRAEQLGARGEPVRKPSLQRPRRRNK
NT seq
1608 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagcagcgatcaacactggcgcttgccgattgtgatccggccgtcctgacggcc
agccgccatccggcccgggtcatccccggctatgtgattttcgtcggggttggactgggc
ggtccgctgcggctgacgctggccggtctgaaggccattgaggaagccgatgtcatcgtc
ctcaatcccggcgtggacgagggactgctggacgaacccgaaatcaccactccggaccgg
gcggtgacggtcgtcgccgacgatcatcccgacctggacaagatcaccacgctcgtccaa
tccgggctgagcgtggtctggctgttggccggcgaccccttgatggacgccgaggcagcg
tcttacacctccgaactcagggccaacggctgtcgtatcgacatggtgccgggcctgtcc
aggctcagtctcgcgatcacgtcgaccggcatcacgccgggaccgggtttccggctgtgg
tccggatcggcagcgatgtccggcgatggtgagtcgttcgtggcgttgctccccgatcag
caggccgacgacatcatcgctcacgccgagcagatcggactgccggccgacacccgcgcc
ctggtggtctccgactacgccaccagcgctcagaagaccactccgacggttctcggtgag
ctggccgacgtgctgaacgccgtccaggatcgcccgtccgccgtgatcatcggtcccgct
gccgtacgcgatcccagcctgaactggttcgaatccaaacccctgttcggctggcatgtg
ctggttccgcgcaccaaggggctgtcgggggccatggaacgccgcctggagcaccacggt
gcggtgccggtgcagataccgacgatctcggtggagccaccgcgcaacccgcagccgatg
gaacgcgccatccagggtctggtcgacggccgctaccagtggatcattttcaactccgcg
caggcggtgcgcgctgtcaccgaacggctggtcgggctcgggctcgattcgcgtgccttc
tccggtctgcgcatcgcggccgtcggcgccgacaccgtgaccgcgcttcgcggctggggt
atcacccccgatctggtgcccgagggcgaggcgcgcagcgaagcactcgcctcagaattt
ccgatcttcgacgatctgctcgaccccatcaaccgcatcttcatcccccgtgccgatgtc
tcggtcgactcgctggtacagagcatgaacgaactgggctgggaggtcgacgatgtggtc
gcctaccgcacggttcgcgccgcgccgccggccgccgagatccgcgatgccatcaaggcc
ggacgattcgacgccgtggtcttcagttctgcctcgaccgtgcggaatatggtcggcatc
gccggcaaaccgcatgtcgacaccatcatcgcggcgatcggcccggccactgtcgccgcc
tgcgaggaggcgaatctgcgggtggatgtggtcgcctcgcagccgaaccaggccgatctc
gtggacgctctggcggcattcgccgtcaaacgggccgagcagctcggcgcccgcggtgaa
ccggtccgcaagccctccctgcagcggcccagaagacgaaacaagtag
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