Catenulispora acidiphila: Caci_8324
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Entry
Caci_8324 CDS
T00967
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
cai
Catenulispora acidiphila
Pathway
cai00860
Porphyrin metabolism
cai01100
Metabolic pathways
cai01110
Biosynthesis of secondary metabolites
cai01120
Microbial metabolism in diverse environments
cai01240
Biosynthesis of cofactors
Module
cai_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
cai_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
cai_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
cai00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Caci_8324
Enzymes [BR:
cai01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Caci_8324
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Caci_8324
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ACU77147
UniProt:
C7QKP8
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Position
complement(9649173..9650957)
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AA seq
594 aa
AA seq
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MTEMVKVLEVLEGAGGVRGVSAQDDKTDGGGEAGMVTTTQRGSASALDSCATTALLAFVG
AGPGDPELLTLRAVALLAGADVIAAEAGLLERLSTHLNPDATLVPVVENERGELGELGDA
TVSLTPASRMKNLLSEVAAGRRVVRLTSGDPGLSGVVAAEAALCAKAGVVYEIVPGVAVS
TAVPLYAGISLGRSSGQGGVRIRSLADVADSAGKPGAGPLGTHETLVMVGPAHLLEAAAA
ALQATGLAKATTPVAVTADGSMTTQRTVASTLARVAIEASALIAAGGEVVVVVGAAVADR
AALSWYETKPLFGWKVLVPRTKEQAEGLSHRLRTYGAVSHEVPTIAVEPPRTPQQMERAV
KGLVTGRYEWVAFTSQNAVKAIREKFEEYGLDARAFAGIKVAAVGEQTAAALVAFGVQPD
LVPSGEQSAAGLLEDFPAYDPVFDPIERVFLPRADIATDTLIAGLIELGWEVDDVTAYRT
VRAAPPPAEVREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHAATVIACIGPQTAKTAEEH
GLRVDVMAPSASVTALADALAAFGESRRLSALSAGEPLYRPSERRPGGRRRSAR
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
gtgacggagatggtgaaggtcctggaggtcctggagggcgccggcggcgtccgcggggtt
tccgcgcaagatgacaagacggacggtgggggtgaggcaggcatggtgacgactactcag
cgaggttcggcctctgcgctcgattcctgcgcgacgacggcgttgctcgccttcgtcggc
gccggtcccggtgatccggagctgctgaccctgcgcgccgtggcgctgctggccggcgcc
gacgtgatcgccgccgaggccggcctgctggagcggctcagcactcacctgaacccggac
gccacgctggtgccggtggtggagaacgagcgcggcgagctgggggagctgggagacgcg
accgtctcgctgaccccggcctcgcggatgaagaacctgctctccgaggtggccgccggc
cgccgcgtggtgcggctgacctccggggacccgggcctgtccggcgtggtggcggccgag
gccgcgctgtgcgccaaggccggcgtggtctacgagatcgtcccgggcgtcgcggtctcc
accgcggtgccgctgtacgccggcatctcgctgggccgctcctcgggccagggcggcgtg
cgcatccgctcgctggccgacgtcgcggactccgccggcaagcccggcgccggaccgctc
ggcacgcacgagacgctggtcatggtgggcccggcgcacctgctggaggcggccgcggcc
gcgctgcaggcgaccggcctggccaaggcgaccaccccggtcgcggtgaccgccgacggc
tcgatgaccacccagcgcaccgtggcctccaccctggcccgggtcgcgatcgaggcctcc
gcgctgatcgcggccggcggcgaggtggtcgtggtggtcggcgccgccgtcgccgaccgg
gccgcgctgtcctggtatgagaccaagccgctgttcggctggaaggtcctggtgccgcgc
accaaggagcaggccgaagggctctcgcaccggctgcgcacctacggcgcggtctcgcac
gaggtgccgaccatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgcggtc
aagggtctggtgaccggccgctacgagtgggtcgcgttcacgtcgcagaacgctgtgaag
gcgatccgcgagaagttcgaggagtacggcctggacgcccgcgcgttcgccgggataaag
gtcgcggcggtcggcgagcagacggcggcggcgctggtcgccttcggcgtgcagccggac
ctggtgccctccggcgagcagtcggcggccgggctcctggaggacttcccggcctacgac
ccggtcttcgacccgatcgagcgggtcttcctgccccgggcggacatcgccaccgacacc
ctcatcgccggcctgatcgagctgggctgggaggtcgacgacgtgaccgcctaccggacg
gtgcgcgcagcgccgccgccggccgaggtccgcgaggcgatcaagggcggcggcttcgac
gcggtcctgttcacctcctcctccacggtccgcaacctggtcggcatcgccggcaagccg
cacgcggcgaccgtgatcgcctgcatcggcccgcagaccgcgaagaccgccgaggagcac
ggactgcgcgtggacgtcatggcgccctcggcgtcggtgacggcgctggccgacgcgctg
gcggcgttcggcgagtcgcgccggctgtccgcgctgtccgcgggcgagccgctctaccgg
ccctccgagcgccggcccggcggacggcggcgctccgcgcgctga
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