Cercocebus atys (sooty mangabey): 105574645
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Entry
105574645 CDS
T07242
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
caty
Cercocebus atys (sooty mangabey)
Pathway
caty00010
Glycolysis / Gluconeogenesis
caty00020
Citrate cycle (TCA cycle)
caty00620
Pyruvate metabolism
caty00785
Lipoic acid metabolism
caty01100
Metabolic pathways
caty01200
Carbon metabolism
caty01210
2-Oxocarboxylic acid metabolism
caty04066
HIF-1 signaling pathway
caty04922
Glucagon signaling pathway
caty05230
Central carbon metabolism in cancer
caty05415
Diabetic cardiomyopathy
Module
caty_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
caty00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105574645 (PDHA1)
00020 Citrate cycle (TCA cycle)
105574645 (PDHA1)
00620 Pyruvate metabolism
105574645 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105574645 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105574645 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105574645 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105574645 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105574645 (PDHA1)
Enzymes [BR:
caty01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105574645 (PDHA1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF1117
Motif
Other DBs
NCBI-GeneID:
105574645
NCBI-ProteinID:
XP_011891104
Ensembl:
ENSCATG00000044567
LinkDB
All DBs
Position
Unknown
AA seq
433 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLCFMRKMLAAVSRVLSGASQ
KPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDG
AANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGM
DILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPI
MLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEV
RGANQWIKFKSVS
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacaccctcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtgcttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aaaccggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaa
attaagaaatgtgaccttcaccgactcgaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
gaagcttgctgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcc
taccgggctcacggctttaccttcacccggggcctttccgtccgagaaattctcgcagag
cttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgcc
aagaacttctacgggggcaatggcatcgtgggagctcaggtgcccctgggcgctgggatt
gctctagcctgtaagtataatggaaaagatgaggtctgcctgactttatatggcgatggt
gctgctaaccagggccagatatttgaagcttacaacatggcagctttgtggaaattacct
tgtattttcatctgtgagaataatcgctatggaatgggaacatctgttgagagagcagca
gccagcactgattactacaagagaggcgatttcattcctgggctgagagtggatggaatg
gatatcctgtgcgtccgagaggcgacaaggtttgctgccgcctattgtagatctgggaag
gggcccatcctgatggagctgcagacttatcgttaccacggacacagtatgagtgatcct
ggagtcagttaccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctatt
atgcttctcaaggacaggatggtgaacagcaatcttgccagtgtggaagaactaaaggaa
attgatgtggaagtgaggaaggagattgaggatgctgcccagtttgccacggccgatcct
gagccacctttggaggagctaggctaccacatctactccagcgacccacctttcgaagtt
cgtggtgccaatcagtggatcaagtttaagtcagtcagttaa
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