Camelus bactrianus (Bactrian camel): 105078270 Help Entry 105078270         CDS       T07534                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism cbai  Camelus bactrianus (Bactrian camel) Pathway cbai04010   MAPK signaling pathway cbai04014   Ras signaling pathway cbai04015   Rap1 signaling pathway cbai04022   cGMP-PKG signaling pathway cbai04066   HIF-1 signaling pathway cbai04068   FoxO signaling pathway cbai04072   Phospholipase D signaling pathway cbai04150   mTOR signaling pathway cbai04151   PI3K-Akt signaling pathway cbai04152   AMPK signaling pathway cbai04211   Longevity regulating pathway cbai04213   Longevity regulating pathway - multiple species cbai04520   Adherens junction cbai04910   Insulin signaling pathway cbai04913   Ovarian steroidogenesis cbai04923   Regulation of lipolysis in adipocytes cbai04930   Type II diabetes mellitus cbai04931   Insulin resistance cbai04932   Non-alcoholic fatty liver disease cbai04960   Aldosterone-regulated sodium reabsorption cbai05010   Alzheimer disease cbai05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cbai00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     105078270 (INSR)    04014 Ras signaling pathway     105078270 (INSR)    04015 Rap1 signaling pathway     105078270 (INSR)    04066 HIF-1 signaling pathway     105078270 (INSR)    04068 FoxO signaling pathway     105078270 (INSR)    04072 Phospholipase D signaling pathway     105078270 (INSR)    04022 cGMP-PKG signaling pathway     105078270 (INSR)    04151 PI3K-Akt signaling pathway     105078270 (INSR)    04152 AMPK signaling pathway     105078270 (INSR)    04150 mTOR signaling pathway     105078270 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     105078270 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105078270 (INSR)    04923 Regulation of lipolysis in adipocytes     105078270 (INSR)    04913 Ovarian steroidogenesis     105078270 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     105078270 (INSR)   09149 Aging    04211 Longevity regulating pathway     105078270 (INSR)    04213 Longevity regulating pathway - multiple species     105078270 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     105078270 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     105078270 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105078270 (INSR)    04932 Non-alcoholic fatty liver disease     105078270 (INSR)    04931 Insulin resistance     105078270 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cbai01001]     105078270 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:cbai04090]     105078270 (INSR) Enzymes [BR:cbai01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      105078270 (INSR) Protein kinases [BR:cbai01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    105078270 (INSR) CD molecules [BR:cbai04090]  Proteins   105078270 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  105078270 NCBI-ProteinID:  XP_010965094 UniProt:  A0A9W3H098 LinkDB All DBs Position Unknown AA seq 1345 aa AA seqDB search MDIRNNLTRLHELANCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLE SLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLAT IDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQK VCPTICKSHGCTAEGLCCHSECLGNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQD WRCVNFSFCQDLHNKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPK VCHLLEGEKTIDSVTSAQELRGCTIVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKI RRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHY NPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSHDKILLKWE PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPMRSNDPKSQNHPG WLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQ IILKWKPPSDPNGNITHYLVFWERQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKH NQTEYEEAAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFIPRKSSSGPGAEDTRP SRRRRALADIGNGTAAVPTLPGFPNASSTSAPTSSEEHRPFEKVVSKESLVISGLRHFTG YRIELQACNQDAPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEP NGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWT EATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNP EYLSASDVFPCSVYVPDEWEVPREKIALLRELGQGSFGMVYEGNARDIVKGEAETRVAVK TVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRS LRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGD FGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPY QGLSNEQVLKFVMDGGYLDQPDNCPDRVTNLMRMCWQFNPKMRPTFLEIVDLLKDDLHPS FPEVSFFHSEENKAPESEELDMEFEDMESVPLDRSAHSQREEAGGRDAGSALGLKRGYEE HIPYTHMNGGKRNGRILTLPRSDPS NT seq 4038 nt NT seq  +upstreamnt  +downstreamnt atggacatccggaacaacctcacccggctgcacgagctggccaactgctccgtcatcgaa ggacatctgcagatactgctgatgttcaaaacgaggcctgaggatttccgagacctcagt ttccccaaactcatcatgatcaccgattacttgctgctcttccgggtctacgggctggag agcctgaaggacctgttccccaacctcacggtcatccggggctcccgcctcttcttcaac tatgcgctggtcatcttcgagatggttcatctgaaggagcttggcctctacaatttgatg aacattacgcggggctcggtccgcatcgagaagaacaatgagctctgctacctggccacc atcgactggtcgcgcatcctggactccgtggaggataattacatcgtgctgaacaaagat gacaacgaggaatgtggggacatttgtccaggcactgccaagggcaaaaccaactgccct gccactgtcatcaatgggcaatttgtcgagcggtgttggacgcacagccactgtcagaaa gtttgtccgaccatctgcaagtcgcacggctgcaccgcggagggcctctgctgccacagc gagtgcttgggtaactgctccgagcccgacgaccccaccaagtgcgtggcctgccgcaac ttctacctggacggccgctgcgtggagacctgcccgcccccctactaccacttccaagac tggcgctgcgtgaacttcagcttctgccaggatctgcacaacaaatgcaagaactctcgg aggcagggctgccaccagtacgtcattcacaataacaagtgcatccccgagtgtccctct gggtacacgatgaattccagcaacttgatgtgcactccatgcctgggcccctgtcccaag gtctgccacctcctggaaggcgagaagaccatcgactcagtgacgtccgcccaggagctc cgaggctgcaccattgtcaacgggagcttaatcatcaacattcgagggggcaacaatctg gcagctgagctggaggccaaccttggactcattgaagaaatttcagggtacctgaaaatc cgccggtcctacgccctcgtgtcactttccttcttccggaagttacgtctgattcgagga gagaccttggagattgggaactactccttctacgccttggacaaccagaacctaaggcag ctgtgggactggagcaaacacaacctcaccatcacgcaggggaaactgttcttccactat aaccccaagctctgcttgtcagaaattcacaagatggaggaagtttcaggaaccaagggg cgccaggagagaaacgacattgccctgaagaccaatggggaccaggcgtcctgtgaaaat gaattacttaaattctcttacattcggacatctcatgacaagatcttgctgaaatgggag ccctattggccccctgacttccgagatctcttggggttcatgcttttctacaaagaggcc ccttatcagaacgtgacagagttcgatggacaggatgcgtgcggctccaacagctggacg gtggtggacattgacccgccgatgaggtccaatgaccccaagtcacagaaccaccccggg tggctgatgcggggtctcaagccctggacccagtacgccatctttgtcaagaccttggtc accttttctgacgaacgccgcacgtacggggccaagagcgacatcatctatgtccagaca gatgccactaatccttccgtcccactggatcccatctcggtttctaattcctcgtcccag attattctgaagtggaagcctccctctgaccccaacggcaacatcacacactacctggtt ttctgggagaggcaggcggaagacagcgagctgtatgaattggattattgcctcaaaggg ctgaagctgccgtcccggacctggtctccgccgtttgagtctgagggctcccagaagcac aatcagaccgagtacgaggaggctgccggagagtgctgctcctgcccgaagaccgactct cagatcctgaaggagctggaggaatcctcgttccggaagacatttgaggattacctgcac aatgtggttttcatccccagaaaatcctcttcaggccctggcgcggaggacaccaggccg tcgcggagacgcagggccctggctgacatagggaatggcacagcggccgtgcccacgctc ccggggttccccaacgcctcctccaccagcgcacccaccagctcggaggagcacagaccc ttcgagaaagtggtgagcaaagagtcactggtcatctcggggctgcgtcactttaccggc taccgcatcgagctgcaggcttgcaaccaagatgcccccgaggagcggtgcagcgtggcc gcctacgtcagcgccaggaccatgcccgaagccaaggccgatgatattgtgggccccgtg acccacgaaatcttcgagaacaacgtcgtccacctgatgtggcaggagcccaaggaaccc aacggtctgatcgtgctctatgaagtgagctaccgacgatacggcgatgaggagctgcac ctgtgcgtctctcgaaggcatttcgctctggagcggggctgcaggctgcgcgggctgccg cccgggaattacagcgtgagagttcgggccacctccctggcgggcaacggctcctggaca gaagccacttatttctatgtgacagattatttagacgtcccatcaaatattgcaaagatt atcatcggccccctcatctttgtatttctcttcagtgttgtgattgggagtatttatctg ttcctgagaaagaggcagccggatgggccactgggaccactgtatgcttcttcgaacccc gagtacctcagtgccagcgatgtgttcccgtgttctgtgtacgtgccggacgagtgggag gtgccccgggagaagatcgcgctgctgcgagagctcgggcagggctccttcggcatggtg tacgagggcaacgccagggacatcgtcaagggcgaggcggagacccgcgtggcggtgaag acggtcaacgagtcggccagcctgcgagaacggattgagtttctcaacgaggcctcggtc atgaagggcttcacctgccaccacgtggtccgcctcctgggggtggtgtccaaaggccag ccgacactggtggtgatggagttgatggctcacggagacttaaagagctacctccgttcc ctgcggccggaggccgagaataaccctggtcgccctccccctacgctgcaagagatgatt cagatggcggcggagattgccgatgggatggcgtacctgaacgccaagaagttcgtgcac cgggacctcgcagctcggaactgcatggtcgctcatgattttaccgtcaaaatcggagac tttggaatgaccagagacatctacgaaacggactactaccggaaagggggcaagggcctg ctccccgtgcggtggatggcacccgaatccctgaaggacggggtcttcaccacttcttcc gacatgtggtccttcggcgtggtcctctgggaaattaccagcttggcagaacagccttac caaggcctatctaatgagcaggtgttgaaattcgtcatggatggagggtatctggatcaa cctgacaactgtccagacagagtcaccaacctgatgcgcatgtgctggcagttcaacccc aagatgcggccgaccttcctggagatcgtcgacctgctcaaggacgacctgcaccccagc tttcccgaagtttccttcttccacagcgaggagaacaaggcgccggagagcgaggagctg gacatggagtttgaggacatggagagcgtcccgctggaccggtcggcacactcgcagcgg gaggaggccgggggccgggacgcggggtcggcgctggggctgaagcggggctacgaggag cacatcccctacacccacatgaacgggggcaagaggaacggccgcatcctgaccctgccg cggtccgacccttcctaa

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