Castor canadensis (American beaver): 109682695 Help Entry 109682695         CDS       T04791                                  Symbol Sphk2 Name (RefSeq) sphingosine kinase 2   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism ccan  Castor canadensis (American beaver) Pathway ccan00600   Sphingolipid metabolism ccan01100   Metabolic pathways ccan04020   Calcium signaling pathway ccan04071   Sphingolipid signaling pathway ccan04072   Phospholipase D signaling pathway ccan04148   Efferocytosis ccan04370   VEGF signaling pathway ccan04371   Apelin signaling pathway ccan04666   Fc gamma R-mediated phagocytosis ccan05152   Tuberculosis Module ccan_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:ccan00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     109682695 (Sphk2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     109682695 (Sphk2)    04371 Apelin signaling pathway     109682695 (Sphk2)    04020 Calcium signaling pathway     109682695 (Sphk2)    04072 Phospholipase D signaling pathway     109682695 (Sphk2)    04071 Sphingolipid signaling pathway     109682695 (Sphk2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     109682695 (Sphk2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     109682695 (Sphk2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     109682695 (Sphk2) Enzymes [BR:ccan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      109682695 (Sphk2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  109682695 NCBI-ProteinID:  XP_020013661 UniProt:  A0A8B7U2P0 LinkDB All DBs Position Unknown AA seq 624 aa AA seqDB search MAPPLAASTPLLHGEFGSYPACGRRLALTLTSQALHIQRLRPKPEARPRGGLVSLAEVSG CCTLQSRSPSDSAAYLCIYTYPQGRRRRGGRRRAARIFQADGATTYEENHAEAQRWATAL MCLLRGVPLPGDGEITPELLPRKPRLLLLVNPFGGRGLAWQLCRDHVLPMISEAGLSFNL IQTERQNHARELVQGLNLSEWDSIVTVSGDGLLYEVLNGLLDRPDWEEAVKMPLGILPCG SGNALAGAVNQFGGFEPALGLDLLLNCSLLLCRGGSHPLDLLSVTLASGSRCFSFLSVAW GFVSDVDIQSERFRALGSARFTLGTVLGLATLHTYRGRLSYLPAAVESALPASAHGLPRA KSELTLAPAPVPPVAHSPLHRSVSDLPLPLPQPHPALTSPGSPEPLPMLSLNGGGPELAE DWGGAGDAPLSPDPLLPSPPSSPKAAPLSPITEVPPEMPASSKPPPPTPGGAEGSTRGPP DHLLPPLGTPLPSDWVTMEEDFVLMLAISPSHLSADMVAAPHARFDDGLVHLCWVRSGIS RAALLRIFLAMERGNHFSLGCPHLGYAAVRAFRLEPLTPRGMLTVDGEQVEYGPLQAQMH PGLGTLLTGPPGRAGPEPRAGPGS NT seq 1875 nt NT seq  +upstreamnt  +downstreamnt atggccccaccactggctgccagcaccccactcctgcatggggagtttggctcctaccca gcctgtggccggcgattggctctcaccctcacatcacaggccctgcacatacagcggctg cgcccaaagccggaagcccggccccggggcggcctggtgtccctggctgaggtttctggc tgctgcaccctgcagagccgcagcccctcggactctgcagcctacctgtgcatctacacc tatccccagggccggcgccgccgtgggggccgacgccgagccgcccgcatcttccaggca gatggagcaaccacctatgaggagaaccacgccgaggcccagcgctgggcaactgccctc atgtgtctgctccgaggagtaccactccctggggacggggagatcaccccagagcttctg ccccggaaacctcggttgctcctattggtcaatccctttggagggcggggcctggcctgg cagttgtgtagggaccacgtgttgcccatgatctctgaagctggtctatccttcaacctc attcagacagaacgacagaaccacgcccgggagctggtccaggggctgaacctgagcgag tgggacagcatcgtcacagtctctggagatgggctgctctatgaggtgctgaatgggctc ctagatcgccctgactgggaggaggctgtgaaaatgccattagggatcctcccctgtggc tcaggcaacgcgctggctggagcagtaaaccagttcgggggatttgagccggccctaggc ctcgacctgctgctcaattgctcactgctgctgtgccggggtggcagccacccactggac ctgctctctgtgacactggcctcaggatcccgttgtttctccttcctgtctgtggcctgg ggcttcgtgtcggacgtggacatccagagtgagcgtttcagggccctgggcagtgcccgc ttcacactgggcacggtgctgggcctcgccaccttacacacttaccgcggacgcctctcc tacctccctgccgccgtggagtcagccttgcccgcctctgcccacggcctgccccgggcc aaatcagagctgaccctggccccggccccagtgccacctgtggcccactcgcccttgcat cgctcagtgtccgacctgcccctgcccttgcctcagccccaccctgccttgacctcccct ggctcacccgagcccctgcccatgctgtctctcaatggcgggggcccagagctcgcggag gactggggtggtgctggggatgccccactgtccccagacccactcctgccctcgcccccc agctctcccaaggcagctccactgtctcccatcacagaagtgcccccagaaatgccagcg tcctccaagcccccgcctcccacccctgggggtgcagaaggaagtactaggggcccaccc gaccacctgctgcctccgttgggcaccccactgccctcagactgggtgacgatggaggag gacttcgtgctcatgttggccatttctcccagccacctgagcgccgacatggtggcggct ccgcacgcgcgctttgacgacggcctggtgcacctgtgctgggtgcggagcggcatttcc cgggccgcgctgctgcgcattttcctggccatggagcgggggaaccacttcagtctgggc tgtccgcacctgggatatgccgcggtccgtgccttccgcctcgagcccctcacgcctcgc ggcatgctcacggtggacggcgagcaggtggagtatgggccgctccaggcgcagatgcat cccggcctcggtaccttgctcaccgggccgccaggccgcgctgggccagaaccccgagct ggacccggctcttaa

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