Castor canadensis (American beaver): 109688063
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Entry
109688063 CDS
T04791
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00010
Glycolysis / Gluconeogenesis
ccan00020
Citrate cycle (TCA cycle)
ccan00620
Pyruvate metabolism
ccan00785
Lipoic acid metabolism
ccan01100
Metabolic pathways
ccan01200
Carbon metabolism
ccan01210
2-Oxocarboxylic acid metabolism
ccan04066
HIF-1 signaling pathway
ccan04922
Glucagon signaling pathway
ccan05230
Central carbon metabolism in cancer
ccan05415
Diabetic cardiomyopathy
Module
ccan_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
109688063
00020 Citrate cycle (TCA cycle)
109688063
00620 Pyruvate metabolism
109688063
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
109688063
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
109688063
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
109688063
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
109688063
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
109688063
Enzymes [BR:
ccan01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
109688063
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
109688063
NCBI-ProteinID:
XP_020021890
UniProt:
A0A250YHC0
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLFGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgctgtctcccgcgtgttgttcggcgctgcccagaagccggca
agcagagtactagtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccggctggaagagggccctcctgtcacaacagtgcttactagggaggat
gggctcaaatactataggatgatgcagactgtgcgccgaatggaattaaaggcagatcag
ctgtataaacaaaaaattattcgtggtttctgtcacctgtgtgatggtcaggaagcctgc
tgtgtgggccttgaggctggcataaatcccacagaccatcttatcacagcctaccgggct
catggcttcacctttactcggggcctttctgtccgagaaattcttgcagagctaacagga
cgaagaggaggttgtgctaaagggaagggaggatcaatgcacatgtatgcaaagaacttc
tatgggggcaatggcattgttggagctcaggtgcccctgggagctggaattgctttggcc
tgcaagtataatggaaaagatgaagtctgtttgacgttatatggtgacggcgctgctaac
cagggtcagatatttgaagcttacaatatggcggccctatggaaattaccttgtattttc
atctgtgagaataaccgctatggaatgggaacatctgttgagagagcagcggccagcacc
gattactacaagagaggagattttattcctgggctgagggtagatggaatggatatctta
tgtgtccgagaggcaacaaagtttgcagctgcctattgtagatctgggaaggggcccatc
ctgatggagctgcagacttaccgttaccatggacacagtatgagtgaccctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgttgaagaactaaaggaaatcgatgtt
gaagtgaggaaagaaattgaggatgccgcccagtttgccacagctgatcctgagccaccg
ttggaggaactaggctatcacatctacagcagcgatccaccctttgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa
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