Clostridioides difficile CD196: CD196_0235
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Entry
CD196_0235 CDS
T00997
Symbol
purL
Name
(GenBank) formylglycinamidine ribonucleotide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cdc
Clostridioides difficile CD196
Pathway
cdc00230
Purine metabolism
cdc01100
Metabolic pathways
cdc01110
Biosynthesis of secondary metabolites
Module
cdc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cdc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CD196_0235 (purL)
Enzymes [BR:
cdc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CD196_0235 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
TRM
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
CBA60474
UniProt:
A0A0H3MYN5
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All DBs
Position
282721..286527
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AA seq
1268 aa
AA seq
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MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIENLRILNRYDVEGISEEV
YENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQRGDWAAQCVQIVNQGIRP
AINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKPETLKMETEIPTTVEVLDGFI
DLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNPTITEIKVLDTYWSDHCRHTTFM
TEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRHKDICLMDIATVAVKELKKNGKLND
LDESEEINACSINVDVEVDGKMEKYLVMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSG
RSYVYQAMRVTGSADPRTTLEDTLPGKLMQRKITTEAAHGYSSYGNQIGLTTGQVAEVYD
ENFVAKRMEIGAVIAAVPKENVVRERPEAGDVIVLLGGKTGRDGCGGATGSSKEHSEESI
LTCSAEVQKGDAPNERKIQRFFRNKEVAQMIKRCNDFGAGGVCVAIGEIADSLDINLDLV
PKKYDGLDGTELAISESQERMAVAIKKENKDKFIQLAVEENLEATHVATVTDTGYLRMFW
NGKAIVDINREFLDTNGVKQTTDVHVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSD
LNVCSQKGLVEMFDNTIGGNTVLMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYN
PKVGKWSPFHGALYAVVESVCKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLG
AFYAQSKFEIPAIGGKDSMSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVML
CVNKAENDVVDFEELKRNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFS
EEAEKTFTDDKLFEASYGNIVLELANDDLCMLEGYNYVVLGSTTKEASIFIKGEELALDE
LYKAHCSTLEPIFPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYD
SARAFERVGANANIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKF
IATVFRNPRVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNN
IGRHQAKIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQ
YVDFNNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVFKNIIGEKDQKIF
ESGVKYFR
NT seq
3807 nt
NT seq
+upstream
nt +downstream
nt
atgttgaatactgaaaataaagactcaatggttagaagagtattagttgaaaaaagagaa
ggttttgaccttgaggctaaagctttaaaaaaagacttagtagaaagtttacacatagat
aatatagaaaatttaagaatattaaatagatatgatgtagaaggaatatcagaagaagtt
tatgaaaatgcagcaaagacaatattctctgaaccaaatttagatgtagtatattatgaa
gaaataccaaaattaaatgatgaaagagtatttgcaatagaatttcttcctggtcaatac
gaccaaagaggtgattgggcagctcaatgtgtacaaattgtaaatcaagggataagacct
gctattaatacagcaaaagtttatatattatcaggcaaaataactgatgaagagttttct
aaaataaaagattactgtataaatccagtagatagtagagaagcatctttagaaaaacca
gaaacattaaaaatggaaactgaaataccaacaacagttgaagtattagatggatttata
gatttagatgaaaatggattaagaacatttgtaagtgaaaaaggattagcaatgacttta
ggagacttacaacacgttcaaaaatactttaaagatacagaaaagagaaatccaactata
acagaaataaaagtattagatacttattggtctgatcattgtagacatactacttttatg
actgaaatagaaaatgtaaagatagaagatggtaagtttaatgatatagtaaaagaagcg
tatcaaatgtatcttaactcaagagacaatgtatatgtgaacagacataaagatatatgt
ttaatggatatagccactgttgcagtaaaagaattaaagaagaatgggaaattaaatgac
ctagatgaaagtgaagaaataaatgcatgtagtataaacgtagatgttgaagttgatggt
aagatggaaaaatatctagtaatgtttaaaaatgaaactcacaaccatccaactgaaata
gaaccatttggtggagcagctacttgtttaggtggagctataagagacccattatcagga
agaagttatgtttatcaagcaatgcgtgttacaggaagtgctgacccaagaacgacttta
gaagatactttacctggaaaacttatgcaaagaaaaataactacagaagctgctcatgga
tatagttcatatggtaaccaaataggtcttacaactggacaagttgcagaagtatatgat
gaaaactttgttgcaaagagaatggaaataggtgcagttatagcagcagtaccaaaagag
aatgtagtaagagaaagacctgaagcaggagatgtaatagttcttcttggaggaaaaaca
ggaagagatggttgtggaggggcaactggttcatctaaagaacatagtgaagagtcaatc
ttaacttgtagtgcagaagttcaaaaaggagatgctcctaacgaaagaaaaatacaaaga
ttctttagaaataaagaagttgctcaaatgataaaaagatgtaatgattttggagcaggt
ggagtttgtgttgctataggagagattgctgatagtttagatataaacttagacttagta
cctaaaaaatacgatggacttgatggaactgagcttgcaatttcagagtcacaagagcgt
atggcagtagctataaaaaaagaaaataaagataaatttatacaattagcagtagaagaa
aacttagaagctacacatgtagctacagtaacagatacaggatatttaagaatgttctgg
aatggaaaagcaattgtagatataaatagagagttcttagatacaaacggagtaaaacaa
actactgatgtccatgttactaaagtagatgaagaaaatacattctttagctctaatgaa
atagtaaaagatgttaagtgtgcaagtatgaaagacaagtttacaaaagtattatctgac
cttaatgtttgttctcaaaaaggattagtagagatgtttgataatacaattggtggtaat
acagtacttatgccatttggaggaaagtatcaagcgactccaacacaaggtatggttgct
aagataccagtacttggaggagaaactaatacttctacaataatgacttatggatataat
ccaaaggtaggaaaatggagtccattccatggtgccttgtacgcagtagtagaatctgtg
tgtaaattggttgctattggaggaaattatagtacaacaagacttacattccaagagtat
tttgaaaaacttggtaacaatccagaaaaatggggtaaaccattctcagcacttttagga
gcattttatgcacaaagtaaatttgagatacctgctataggtggaaaagacagtatgtct
ggtacatttaaagatatcgaagttccaccaacattagtttcatttgctgttgatacagta
gatgcgaagaaagtagtatctccagaatttaaaaaagcagactcaaaagtagtaatgtta
tgtgtaaacaaggcagaaaatgatgttgtagattttgaggaattaaagagaaacttagac
aaagtaagagaacttatacatggaaataaagttttatcaacatatgcattaggatttgca
ggtgtaggtgaagcaataagtaaaatggcttttggtaataaaataggatttaagtttagt
gaagaagctgaaaaaacatttacagatgataaattatttgaggctagttatggaaatata
gtacttgaattagcaaatgatgatttatgtatgttagaaggatacaattatgttgtgctt
ggaagtacaactaaagaagctagtatatttatcaaaggtgaagaacttgcattagatgaa
ttatataaagcacactgtagtactttagagcctatattcccaactaaaacagaagaagta
aaatcaaagatagagactataagttatatatcacaaggagaagctaaaaaatcatcatta
agtatagctactccaagagtatttataccagcatttcctggaacaaactgtgaatatgac
tctgcaagagcatttgaaagagtaggagctaatgcaaacataagagtattcaagaattta
acttataaagacatagaagattctatagatacaatagtaaacgaaataaaatcttctcaa
ataataatgttaccaggtggatttagtgctggtgatgagccagatggttctggtaaattt
atagctactgtatttagaaatcctagagtgcaagaagctataaatgaatttttaactcaa
aaagatggactaatgttaggtatctgtaatggattccaagtattaattaaattaggatta
gttccatatggagaaataagagttccaagtgaaagtgctccaacacttacttacaataat
attggtcgtcatcaagctaagattgctagaactagaatttcatctaataaatctccttgg
ttagctcaaactaatgttggagatattcataatatagcaatttctcatggagaaggtaaa
tttgttgctagtgaagatgttatgagagaattaattgctaatggacaagtagcaactcaa
tatgttgactttaataatgaagctacttatgatattgagtttaatccaaatggttcattc
tatgctgttgaaggtataactagtgctgatggtagagtgtttggtaaaatgggacattct
gagagaattggtgaggaagtatttaagaatattataggtgaaaaagaccaaaagatattt
gaatctggagttaaatattttagataa
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