Corynebacterium diphtheriae INCA 402: CDB402_1985
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Entry
CDB402_1985 CDS
T01688
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cdh
Corynebacterium diphtheriae INCA 402
Pathway
cdh00230
Purine metabolism
cdh01100
Metabolic pathways
cdh01110
Biosynthesis of secondary metabolites
Module
cdh_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cdh00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CDB402_1985 (purL)
Enzymes [BR:
cdh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CDB402_1985 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
GATase_3
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
AEX47281
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Position
2149840..2153556
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AA seq
1238 aa
AA seq
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MDARLAIRRSPNFRDEERALLRSLNNLEGAPLTDVQIINVYDVFDATEADITALTNSVVS
DPKVDTVLTTAELDTIVEQAPAHLAVEPLPGQYDQRADAAEQALRLLNPHTNARVTSGEL
YIFSDLTEEAFANIRDYLINPVEAGEKNLDVLRAPSMGDIAPLKQYPDFLELDDAGLSAL
LASEGMAMSLADLKLIQEYFRTEGRTPTEVELAALDTYWSDHCRHTTFNTELTEITNSSS
RYGAQLDRALKRYDELREANGRAHKPRTLMDLGTIMGRELRRNGTMTDQEVSEEINACSV
YVDVDTPEGDKPWLLMFKNETHNHPTEIEPFGGASTCLGGAIRDPLSGRSWVYQAMRISG
AGDINTPRTETIDGKLPQADISARATHGYSSYGNQIGLATTSVRELIHPGYVAKRMELGA
VVAAAPQENVKRLEPQPDDVVIILGGRTGRDGVGGATGSSKAHDEESLARSGAEVQKGNP
VNERKIQRLFRRPEIAQMIVRCNDFGAGGVSVAVGELTDSIDIHLDRVPLKYAGLNAREI
AISESQERMAVVVRPEDAAAFIEAAATENIEAVELATVTDSGRLRMFLGKDLVLDLSREF
LETNGAARSQSVEMRDAGDVEKPAQPATILESLTRHGSQEGMVEQFDATVGRSTVLMPYG
GRTQKTDELASVQTFPVPGGSHTASVMTYGFSPELADVSPYLMGSYSVVEALSRLVATGA
NARGAWLSVQEYFQRLDQKPELWGEVTQALLGLLEAQDAFEVAAIGGKDSMSGTYGDDLH
VPATLVTFAVATMDARRTLSAAIPSGEFDVYHLAHTPLETGEVNYEQLRANFDAFHELAA
TGTLSAASPIIPSGLGATIVNMLLGNELGFQGTATTNAALGGLVFAVPAGTAVELADAQL
IGHTNPSGEIAFGEETFTIAQALDTLERDYREVYPLNVTTADVEALPEFATALRTADSDS
EEANASAGDKAVHVLLPVFPGTNSEYDMAEAFEAAGATTEFHIIRNLNSEMLAADTEAFI
TKLQSANILALSGGFSLGDEPDGSAKFMAAFLRSDTVAAAIKDFVARDGLVLGICNGFQA
LVKSGFLPYGDPAKMTAESPTLAHNRQLRHVSRIATTRVSSVASPWLSTFTPGQQHLMPV
SHGEGRFVVSEKEAQALFSAGQVAFQYVDAEGTPTMEAPANPNGSNYAIEGIISPDGRIL
GKMGHPERFRDGLMRNIPGMEVQDIFANAVNYCRKSQR
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
atggacgcgcgtcttgccattcgccgctcacccaacttccgcgacgaggagcgcgcgcta
ctgcgttccctcaacaacttagaaggcgcccccctcaccgacgtccagatcatcaatgtc
tacgacgtcttcgacgccaccgaagcagacatcaccgccctaacaaactccgtagtcagc
gaccccaaggtggacaccgtacttactacagctgagctcgacaccatcgtcgaacaagca
ccagctcatctcgcagtcgaaccacttcctggccaatatgaccagcgcgccgacgcagcc
gaacaagcattacgactgctcaacccccacaccaacgcacgtgtgacctccggcgagctt
tatatcttcagcgacctaaccgaagaggcattcgccaacatccgcgactacctaatcaac
cccgtcgaagcaggcgagaaaaacctcgacgtactgcgcgcaccatccatgggcgacatc
gccccactcaagcaatacccagatttccttgagctcgacgacgctggattgagcgcgtta
ctagccagcgaaggcatggccatgagcttggcagacctgaagcttattcaggaatacttc
cgcaccgaaggccgcacccccaccgaggtggaactggcagcactggacacctactggtcc
gatcactgccgccacaccacctttaacaccgagctgacggagatcaccaactccagcagt
cgttacggtgcacagctcgaccgcgcactgaagcgttacgacgaactccgcgaagccaac
ggtcgcgcccataagccacgcaccctcatggacttgggcaccatcatgggccgtgagctg
cgtcgcaacggaaccatgaccgatcaagaagtcagcgaagaaatcaacgcctgctccgta
tacgttgacgtggacaccccagaaggcgacaagccttggctgctgatgttcaaaaacgaa
acccacaaccaccccaccgaaatcgaaccattcggtggcgcatccacctgcctcggtggc
gcaatccgcgaccccctatccggtcgctcctgggtttaccaagcaatgcgcatctccggc
gccggtgacatcaacaccccacgcaccgaaacgatcgacggcaaactcccgcaggcagac
atcagtgcccgcgcaacccacggctactccagctacggcaaccagatcggtctggcaacc
accagcgtccgcgaactgattcacccaggttacgtcgccaagcgcatggaactcggcgcc
gttgtggcagccgcaccacaagaaaatgtcaagcgcctagagcctcaaccagacgacgta
gtgatcatcctcggtggccgcaccggacgcgacggcgtgggcggagccaccggttcctcc
aaggcacacgacgaagaatccttggcacgctcgggtgcagaagtccaaaagggcaacccc
gtcaacgaacgcaagatccaacgcctgttccgccgaccagaaatcgcccaaatgatcgtg
cgctgcaatgacttcggcgcaggtggcgtgtccgtcgcagtcggcgaactcaccgacagc
atcgacatccacctcgatcgcgtaccactgaaatacgccggcctcaacgcccgagaaatc
gccatctccgagtcccaggaacgcatggcagtcgtcgtgcgcccagaagacgcagccgca
ttcattgaagcagccgcaaccgaaaacatcgaggcagtagagctcgccaccgtcaccgac
agcggacgcctacgcatgttcctcggcaaggacctagtcctcgacctctcccgcgaattc
ctcgaaaccaacggcgcagcacgctcccagagcgtagaaatgcgcgatgcaggagacgtc
gaaaagcctgctcagccggcaaccatcctcgaatccttgacccgccacggctcccaagaa
ggcatggtcgaacaattcgacgccaccgtcggacgctccaccgtactcatgccatacggc
ggccgcacccaaaaaaccgacgaactcgcatccgtacaaaccttcccagtgccaggcgga
tcccacaccgcatcggtcatgacctacggattcagcccagagcttgccgacgtctccccc
tacctcatgggctcctactccgtcgtcgaagcactcagccgactcgtcgccaccggtgcc
aacgcacgcggcgcatggctgtccgtccaagaatatttccagcgcctcgaccaaaaaccc
gaactctggggcgaagtaacccaggcactcctgggccttcttgaagcacaagacgccttc
gaagtagctgccatcggcggcaaggactccatgagcggcacctacggcgatgacctgcac
gttcccgcaacgctggtcaccttcgcagtcgcaaccatggacgcacgacgcaccctcagc
gccgccatcccaagcggcgaattcgacgtctaccacctcgcccacaccccgctggaaacc
ggcgaagtcaactacgagcaactccgcgccaacttcgacgccttccatgagctcgccgcc
accggcaccctctcggcagcctcccccatcatcccaagtggtctcggcgccaccatcgtg
aacatgctgctcggcaacgaactcggattccaaggcaccgccaccaccaacgcagccctc
ggtggcctcgtattcgcggtcccagccggcaccgcagtcgagcttgccgacgcccaactc
atcggtcacaccaacccatccggcgagatcgccttcggcgaagaaaccttcaccatcgcc
caagcactcgacaccctagagcgcgactaccgcgaggtctacccccttaacgtaaccacc
gcagacgtagaggccctcccagagtttgcgaccgccctacgcacggcagactcggattct
gaagaagccaacgcctccgccggtgacaaagccgtacatgtgttgcttccagtattccca
ggtactaactccgaatacgacatggccgaggccttcgaagcagcaggtgccaccaccgaa
ttccacatcatccgaaacctcaactcggagatgctggctgctgacacagaagcattcatc
accaagctgcaatccgccaacatcctggcattgtccggcggattctccctcggcgacgaa
ccagacggctccgcaaaattcatggcagccttcctacgctccgacaccgtagccgcagcg
atcaaggacttcgtggctcgcgacggcctcgtcctcggaatctgcaacggcttccaagca
ctggtcaagagcggattcctgccatacggcgaccccgccaagatgaccgcagaatcccca
acgttggcacacaaccgccaactgcgacacgtctcacgcatcgccaccactcgcgtcagc
tccgtagcctccccatggctgagcaccttcaccccaggccagcagcacctcatgccagta
tcccacggcgaaggccgcttcgtagtatccgaaaaggaagcccaagcactgtttagcgca
ggtcaagtagcattccagtatgtggatgccgagggcacccccaccatggaagcacctgcg
aaccccaacggatccaactacgccatcgagggcatcatctccccagatggtcgcatcctc
ggcaagatgggacaccccgagcgcttccgcgacggcctcatgcgcaacattcctggtatg
gaggtccaagacatcttcgctaacgcggtgaactactgccgtaagagtcaacgctag
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